YRC Public Data Repository - Protein Structure Prediction

Protein:	gi\|50123109, gi\|...
Organism:	Pectobacterium atrosepticum SCRI1043
Length:	246 amino acids
Reference:	Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16

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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for gi|50123109, gi|....

Description	E-value	Query Range	Subject Range
gi\|77959977 - gi\|77959977\|ref\|ZP_00823884.1\| COG1587: Uroporphyrinogen-III synthase [Yersinia mollaretii ATCC 4396...	247.0	[0..1]	[246..1]
gi\|77973624 - gi\|77973624\|ref\|ZP_00829170.1\| COG1587: Uroporphyrinogen-III synthase [Yersinia frederiksenii ATCC 3...	246.0	[0..1]	[246..1]
gi\|37528462, gi\|... - gi\|37528462\|ref\|NP_931807.1\| uroporphyrinogen-III synthase [Photorhabdus luminescens subsp. laumondi...	246.0	[0..1]	[246..1]
gi\|77978549 - gi\|77978549\|ref\|ZP_00833977.1\| COG1587: Uroporphyrinogen-III synthase [Yersinia intermedia ATCC 2990...	244.0	[0..1]	[246..1]
gi\|84780865, gi\|... - gi\|85060345\|ref\|YP_456047.1\| uroporphyrinogen-III synthase [Sodalis glossinidius str. 'morsitans'], ...	243.0	[0..1]	[245..1]
gi\|209400120, gi... - gi\|209400120\|ref\|YP_002273320.1\| uroporphyrinogen-III synthase [Escherichia coli O157:H7 str. EC4115... gi\|208821889, gi... - gi\|208821889\|ref\|ZP_03262209.1\| uroporphyrinogen-III synthase [Escherichia coli O157:H7 str. EC4042]... gi\|13364210, gi\|... - gi\|15833988\|ref\|NP_312761.1\| uroporphyrinogen-III synthase [Escherichia coli O157:H7 str. Sakai], gi... gi\|217325408, gi... - gi\|217325408\|ref\|ZP_03441492.1\| uroporphyrinogen-III synthase [Escherichia coli O157:H7 str. TW14588... gi\|187768903, gi... - gi\|187768903\|gb\|EDU32747.1\| uroporphyrinogen-III synthase [Escherichia coli O157:H7 str. EC4196], gi... gi\|75197687, gi\|... - gi\|75197687\|ref\|ZP_00707757.1\| COG1587: Uroporphyrinogen-III synthase [Escherichia coli HS], gi\|1571... gi\|189362583, gi... - gi\|189362583\|gb\|EDU81002.1\| uroporphyrinogen-III synthase [Escherichia coli O157:H7 str. EC4486], gi... gi\|189373205, gi... - gi\|189373205\|gb\|EDU91621.1\| uroporphyrinogen-III synthase [Escherichia coli O157:H7 str. EC869], gi\|... gi\|254795800, gi... - gi\|254795800\|ref\|YP_003080637.1\| uroporphyrinogen III synthase [Escherichia coli O157:H7 str. TW1435... gi\|189001433, gi... - gi\|189001433\|gb\|EDU70419.1\| uroporphyrinogen-III synthase [Escherichia coli O157:H7 str. EC4076], gi... gi\|195938091 - gi\|195938091\|ref\|ZP_03083473.1\| uroporphyrinogen-III synthase [Escherichia coli O157:H7 str. EC4024] gi\|168801134, gi... - gi\|189376692\|gb\|EDU95108.1\| uroporphyrinogen-III synthase [Escherichia coli O157:H7 str. EC508], gi\|... gi\|208735227, gi... - gi\|208813950\|ref\|ZP_03255279.1\| uroporphyrinogen-III synthase [Escherichia coli O157:H7 str. EC4045]... gi\|208809689, gi... - gi\|208809689\|ref\|ZP_03252026.1\| uroporphyrinogen-III synthase [Escherichia coli O157:H7 str. EC4206]... gi\|25501202, gi\|... - pir\|\|H86066 uroporphyrinogen III synthase [imported] - Escherichia coli (strain O157:H7, substrain ... gi\|12518668, gi\|... - gi\|15804392\|ref\|NP_290432.1\| uroporphyrinogen-III synthase [Escherichia coli O157:H7 EDL933], gi\|125... gi\|13364210, gi\|... - gi\|15833988\|ref\|NP_312761.1\| uroporphyrinogen-III synthetase [Escherichia coli O157:H7], gi\|13364210... gi\|188015453, gi... - gi\|188015453\|gb\|EDU53575.1\| uroporphyrinogen-III synthase [Escherichia coli O157:H7 str. EC4113], gi... gi\|168763927, gi... - gi\|189365965\|gb\|EDU84381.1\| uroporphyrinogen-III synthase [Escherichia coli O157:H7 str. EC4501], gi... gi\|168753699, gi... - gi\|189358988\|gb\|EDU77407.1\| uroporphyrinogen-III synthase [Escherichia coli O157:H7 str. EC4401], gi...	242.0	[0..1]	[246..1]
gi\|75209569, gi\|... - gi\|75209569\|ref\|ZP_00709790.1\| COG1587: Uroporphyrinogen-III synthase [Escherichia coli B171], gi\|19... gi\|218363132, gi... - gi\|218556363\|ref\|YP_002389277.1\| uroporphyrinogen-III synthase [Escherichia coli IAI1], gi\|218363132... gi\|157078769, gi... - gi\|75188546\|ref\|ZP_00701813.1\| COG1587: Uroporphyrinogen-III synthase [Escherichia coli E24377A], gi... gi\|218354250, gi... - gi\|218697518\|ref\|YP_002405185.1\| uroporphyrinogen-III synthase [Escherichia coli 55989], gi\|21835425... gi\|209921276, gi... - gi\|209921276\|ref\|YP_002295360.1\| uroporphyrinogen-III synthase [Escherichia coli SE11], gi\|209914535... gi\|75256272, gi\|... - gi\|75256272\|ref\|ZP_00727950.1\| COG1587: Uroporphyrinogen-III synthase [Escherichia coli E22], gi\|193... gi\|193067968, gi... - gi\|75238252\|ref\|ZP_00722251.1\| COG1587: Uroporphyrinogen-III synthase [Escherichia coli E110019], gi... gi\|191166118, gi... - gi\|75230765\|ref\|ZP_00717228.1\| COG1587: Uroporphyrinogen-III synthase [Escherichia coli B7A], gi\|191...	242.0	[0..1]	[246..1]
gi\|218701285, gi... - gi\|218701285\|ref\|YP_002408914.1\| uroporphyrinogen-III synthase [Escherichia coli IAI39], gi\|21837127... gi\|254290495, gi... - gi\|254290495\|ref\|YP_003056243.1\| uroporphyrinogen-III synthetase [Escherichia coli BL21(DE3)], gi\|25... gi\|242379334, gi... - gi\|251787061\|ref\|YP_003001365.1\| hypothetical protein B21_03628 [Escherichia coli BL21], gi\|24237933... gi\|253975646, gi... - gi\|254163745\|ref\|YP_003046853.1\| uroporphyrinogen-III synthetase [Escherichia coli B str. REL606], g... gi\|194438641, gi... - gi\|83585947\|ref\|ZP_00924586.1\| COG1587: Uroporphyrinogen-III synthase [Escherichia coli 101-1], gi\|1...	242.0	[0..1]	[246..1]
gi\|81243166, gi\|... - gi\|82779018\|ref\|YP_405367.1\| uroporphyrinogen-III synthase [Shigella dysenteriae Sd197], gi\|81243166...	241.0	[0..1]	[246..1]
gi\|75512637, gi\|... - gi\|75512637\|ref\|ZP_00735149.1\| COG1587: Uroporphyrinogen-III synthase [Escherichia coli 53638], gi\|1... gi\|124499224, gi... - gi\|124530458\|ref\|ZP_01701116.1\| Uroporphyrinogen-III synthase [Escherichia coli B], gi\|124499224\|gb\|... gi\|170022173, gi... - gi\|170022173\|ref\|YP_001727127.1\| uroporphyrinogen-III synthase [Escherichia coli ATCC 8739], gi\|1697...	241.0	[0..1]	[246..1]

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Predicted Domain #1

Region A:
Residues: [1-246]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MTILVTRPSP TGEQLVTRLR KLGYHAWHSP LIEFSPGREL AGLPAQLHAL HADDLVFALS  60
   61 QHAIHYADPM LARTGTSWPA HLAYYAIGRT TALALHKISA HPVTYPPERE TSETLLQLPE 120
  121 LQDVAGKRAL LLRGNGGREL LGETLIERGA QVTYCECYQR RDVHYDGPEQ SRHWQQIGID 180
  181 KLVITSGEML QRIYTLVPDY YRASWLLGCQ LIVVSERLAE QARQLGWRDI RVADNADNDA 240
  241 LVRALQ

[Run NCBI BLAST on this sequence.]

Detection Method:	PSI-BLAST
Confidence:	44.522879
Match:	1jr2A
Description:	Uroporphyrinogen III synthase (U3S, HemD)
Matching Structure (courtesy of the PDB):

Predicted functions:

Term	Confidence	Notes
uroporphyrinogen-III synthase activity	3.19339392327514	bayes_pls_golite062009
catalytic activity	1.50868196926865	bayes_pls_golite062009
hydro-lyase activity	0.850411184249311	bayes_pls_golite062009
lyase activity	0.0536528882085157	bayes_pls_golite062009

TMHMM	2.0c	PSIPRED	v2.61
SignalP	3.0	COILS	1999
DISOPRED	v0.1	NCBI nr	06/2007
PSI-BLAST	2.2.18	FFAS	ffas03
PDB	06/2007	Pfam	22
HMMER	2.3.2

View Structure Prediction Details

Top Sequence Alignment Hits

Predicted functions: