YRC Public Data Repository - Protein Structure Prediction

Protein:	gi\|30259189, gi\|...
Organism:	Bacillus anthracis str. Ames
Length:	250 amino acids
Reference:	Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16

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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for gi|30259189, gi|....

Description	E-value	Query Range	Subject Range
gi\|42739529, gi\|... - gi\|42783600\|ref\|NP_980847.1\| uroporphyrinogen-III synthase [Bacillus cereus ATCC 10987], gi\|42739529...	5.0E-68	[1..250]	[1..250]
gi\|49478645, gi\|... - gi\|49478645\|ref\|YP_038513.1\| uroporphyrinogen-III synthase [Bacillus thuringiensis serovar konkukian...	9.0E-68	[1..250]	[1..250]
gi\|47556683, gi\|... - gi\|47566653\|ref\|ZP_00237475.1\| uroporphyrinogen-III synthase [Bacillus cereus G9241], gi\|47556683\|gb...	1.0E-67	[1..250]	[1..250]
gi\|52141042, gi\|... - gi\|52141042\|ref\|YP_085786.1\| uroporphyrinogen-III synthase [Bacillus cereus E33L], gi\|51974511\|gb\|AA...	1.0E-67	[1..250]	[1..250]
gi\|163942211, gi... - gi\|89205263\|ref\|ZP_01183834.1\| Uroporphyrinogen III synthase HEM4 [Bacillus weihenstephanensis KBAB4... gi\|229169205, gi... - gi\|229169205\|ref\|ZP_04296919.1\| Uroporphyrinogen III synthase HEM4 [Bacillus cereus AH621], gi\|22861...	2.0E-67	[1..250]	[1..250]
gi\|228902992, gi... - gi\|228902992\|ref\|ZP_04067132.1\| Uroporphyrinogen III synthase HEM4 [Bacillus thuringiensis IBL 4222]... gi\|75759962, gi\|... - gi\|75759962\|ref\|ZP_00740031.1\| Uroporphyrinogen-III synthase [Bacillus thuringiensis serovar israele... gi\|228792145, gi... - gi\|228967566\|ref\|ZP_04128592.1\| Uroporphyrinogen III synthase HEM4 [Bacillus thuringiensis serovar s... gi\|218899631, gi... - gi\|218899631\|ref\|YP_002448042.1\| uroporphyrinogen-III synthase [Bacillus cereus G9842], gi\|218545013...	2.0E-67	[1..250]	[1..250]
gi\|152976880, gi... - gi\|89200307\|ref\|ZP_01179061.1\| Uroporphyrinogen III synthase HEM4 [Bacillus cereus subsp. cytotoxis ...	9.0E-67	[1..248]	[1..248]
gi\|229048180, gi... - gi\|229048180\|ref\|ZP_04193749.1\| Uroporphyrinogen III synthase HEM4 [Bacillus cereus AH676], gi\|22872... gi\|29898109, gi\|... - gi\|30022551\|ref\|NP_834182.1\| uroporphyrinogen-III synthase [Bacillus cereus ATCC 14579], gi\|29898109... gi\|229152665, gi... - gi\|229152665\|ref\|ZP_04280853.1\| Uroporphyrinogen III synthase HEM4 [Bacillus cereus m1550], gi\|22863... gi\|229129755, gi... - gi\|229129755\|ref\|ZP_04258722.1\| Uroporphyrinogen III synthase HEM4 [Bacillus cereus BDRD-Cer4], gi\|2...	1.0E-66	[1..250]	[1..250]
gi\|88945102, gi\|... - gi\|88945102\|ref\|ZP_01148322.1\| Uroporphyrin-III C-methyltransferase, C-terminal [Desulfotomaculum re...	3.0E-64	[5..248]	[255..505]
gi\|25315418 - pir\|\|AC2237 uroporphyrinogen III methylase [imported] - Nostoc sp. (strain PCC 7120) gi\|17230942, gi\|... - gi\|17230942\|ref\|NP_487490.1\| uroporphyrinogen III methylase [Nostoc sp. PCC 7120], gi\|17132583\|dbj\|B...	2.0E-63	[4..248]	[259..513]

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Predicted Domain #1

Region A:
Residues: [1-250]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MNALAGKTVL ITRAQHQAKQ MSVAVKEKSG IPLEIPLLRM EGMFHRQIQH IAGQLHSYDW  60
   61 VIFTSKNGVA FFLDCLGKKL PVTTKIAAVG VKTKLELEKR GYHVDFVPTS FVAEAFAEEF 120
  121 VKRLSGNERI LFPKGNLARE VIPVALREIG VSLDELIVYG TKVNIEKKQE LIAALKLGKV 180
  181 DIITFTSPST VTSFVRLLEG TNWREWTKKC TIACIGPITE KEASLYFPHV IMPKEYTVEA 240
  241 LLQCVCESIK

[Run NCBI BLAST on this sequence.]

Detection Method:	PSI-BLAST
Confidence:	42.39794
Match:	1jr2A
Description:	Uroporphyrinogen III synthase (U3S, HemD)
Matching Structure (courtesy of the PDB):

Predicted functions:

Term	Confidence	Notes
uroporphyrinogen-III synthase activity	3.19339392327514	bayes_pls_golite062009
catalytic activity	1.50868196926865	bayes_pls_golite062009
hydro-lyase activity	0.850411184249311	bayes_pls_golite062009
lyase activity	0.0536528882085157	bayes_pls_golite062009

TMHMM	2.0c	PSIPRED	v2.61
SignalP	3.0	COILS	1999
DISOPRED	v0.1	NCBI nr	06/2007
PSI-BLAST	2.2.18	FFAS	ffas03
PDB	06/2007	Pfam	22
HMMER	2.3.2

View Structure Prediction Details

Top Sequence Alignment Hits

Predicted functions: