YRC Public Data Repository - Protein Structure Prediction

Protein:	gi\|30259125, gi\|...
Organism:	Bacillus anthracis str. Ames
Length:	381 amino acids
Reference:	Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16

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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for gi|30259125, gi|....

Description	E-value	Query Range	Subject Range
gi\|167039810, gi... - gi\|167039810\|ref\|YP_001662795.1\| cysteine desulfurase [Thermoanaerobacter sp. X514], gi\|166854050\|gb...	2.0E-89	[1..379]	[1..378]
gi\|20808820, gi\|... - gi\|20808820\|ref\|NP_623991.1\| cysteine sulfinate desulfinase/cysteine desulfurase [Thermoanaerobacter... gi\|20808820 - gi\|20808820\|ref\|NP_623991.1\| Cysteine sulfinate desulfinase/cysteine desulfurase and related enzyme ...	3.0E-89	[1..379]	[1..378]
gi\|241903579, gi... - gi\|241903579\|ref\|ZP_04788301.1\| cysteine desulfurase NifS [Thermoanaerobacter brockii subsp. finnii ... gi\|167039427, gi... - gi\|167039427\|ref\|YP_001662412.1\| cysteine desulfurase [Thermoanaerobacter sp. X514], gi\|166853667\|gb... gi\|76588521, gi\|... - gi\|76796110\|ref\|ZP_00778478.1\| Aminotransferase, class V [Thermoanaerobacter ethanolicus ATCC 33223]...	1.0E-87	[1..379]	[1..378]
gi\|83573402, gi\|... - gi\|83590488\|ref\|YP_430497.1\| aminotransferase, class V [Moorella thermoacetica ATCC 39073], gi\|83573...	2.0E-85	[1..379]	[1..379]
gi\|82401628, gi\|... - gi\|82500379\|ref\|ZP_00885796.1\| cysteine sulfinate desulfinase/cysteine desulfurase and related enzym...	2.0E-85	[2..379]	[4..380]
gi\|78044327, gi\|... - gi\|78044327\|ref\|YP_361012.1\| cysteine desulfurase [Carboxydothermus hydrogenoformans Z-2901], gi\|779...	2.0E-84	[1..380]	[1..380]
gi\|88950955, gi\|... - gi\|88950955\|ref\|ZP_01153529.1\| Aminotransferase, class V:Aromatic amino acid beta-eliminating lyase/...	7.0E-84	[1..379]	[33..408]
gi\|48858274, gi\|... - gi\|67916379\|ref\|ZP_00510092.1\| Aminotransferase, class V [Clostridium thermocellum ATCC 27405], gi\|6... gi\|196197075, gi... - gi\|196253491\|ref\|ZP_03152116.1\| cysteine desulfurase NifS [Clostridium thermocellum DSM 4150], gi\|19...	1.0E-83	[4..380]	[7..382]
gi\|219669599, gi... - gi\|68208042\|ref\|ZP_00560179.1\| Aminotransferase, class V [Desulfitobacterium hafniense DCB-2], gi\|68... gi\|89334620, gi\|... - gi\|89895172\|ref\|YP_518659.1\| hypothetical protein DSY2426 [Desulfitobacterium hafniense Y51], gi\|893...	5.0E-83	[1..379]	[1..380]
gi\|150015982, gi... - gi\|82748254\|ref\|ZP_00910741.1\| iron-sulfur cofactor synthesis protein [Clostridium beijerincki NCIMB...	6.0E-83	[1..379]	[1..378]

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Predicted Domain #1

Region A:
Residues: [1-381]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MERIYLDHAA TSPTHLEVVE KMIPYMTETF GNPSSIHFYG RQTRHAVDEA RRACARSIHA  60
   61 NPNEIIFTSG GTEADNLALI GVARANRHKG NHIITTQIEH HAILHTCELL EREGFEVTYL 120
  121 PVDETGRVQV SDIQKALTEE TILVSVMFGN NEVGTMQPIA EIGKLLKEHQ AYFHTDAVQA 180
  181 YGLVEINVKE FGIDLLSISA HKINGPKGVG FLYAGTNVKF EPLLIGGEQE RKRRAGTENV 240
  241 PSIVGLQHAI LLAEKTREQK NAQYEEFKDI MVSVFQNEDI TFEVNGNLEY RLPHVLNISF 300
  301 TGMNIEPFLV NLDLAGIAVS SGSACTAGSI DPSHVLVAMF GKDSDQIRSS VRFSFGLGNT 360
  361 KEQIEKAAYE TVKIVKRLTQ N

[Run NCBI BLAST on this sequence.]

Detection Method:	PSI-BLAST
Confidence:	82.154902
Match:	1p3wB
Description:	Cysteine desulfurase IscS
Matching Structure (courtesy of the PDB):

Predicted functions:

Term	Confidence	Notes
catalytic activity	2.29878871754893	bayes_pls_golite062009
glycine dehydrogenase (decarboxylating) activity	2.16315837695677	bayes_pls_golite062009
oxidoreductase activity, acting on the CH-NH2 group of donors, disulfide as acceptor	2.16315837695677	bayes_pls_golite062009
transferase activity	1.88724762473867	bayes_pls_golite062009
transferase activity, transferring nitrogenous groups	1.28316822767388	bayes_pls_golite062009
transaminase activity	1.24990480711889	bayes_pls_golite062009
carbon-sulfur lyase activity	0.698312655247044	bayes_pls_golite062009
cystathionine gamma-lyase activity	0.505859361763689	bayes_pls_golite062009
cystathionine beta-lyase activity	0.27933426619091	bayes_pls_golite062009
glycine hydroxymethyltransferase activity	0.271623203801431	bayes_pls_golite062009
ligase activity	0.234633631111721	bayes_pls_golite062009
O-phospho-L-serine:2-oxoglutarate aminotransferase activity	0.234399054481664	bayes_pls_golite062009
cysteine desulfurase activity	0.193311362223799	bayes_pls_golite062009
methyltransferase activity	0.103986924428507	bayes_pls_golite062009
transferase activity, transferring one-carbon groups	0.0254276656964899	bayes_pls_golite062009

TMHMM	2.0c	PSIPRED	v2.61
SignalP	3.0	COILS	1999
DISOPRED	v0.1	NCBI nr	06/2007
PSI-BLAST	2.2.18	FFAS	ffas03
PDB	06/2007	Pfam	22
HMMER	2.3.2

View Structure Prediction Details

Top Sequence Alignment Hits

Predicted functions: