YRC Public Data Repository - Protein Structure Prediction

Protein:	gi\|30264076, gi\|...
Organism:	Bacillus anthracis str. Ames
Length:	762 amino acids
Reference:	Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16

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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for gi|30264076, gi|....

Description	E-value	Query Range	Subject Range
gi\|89104874 - gi\|89104874\|ref\|ZP_01177405.1\| COG0620: Methionine synthase II (cobalamin-independent) [Yersinia pes... gi\|167426239, gi... - gi\|167426239\|ref\|ZP_02317992.1\| 5-methyltetrahydropteroyltriglutamate--homocysteine S-methyltransfer... gi\|22124357, gi\|... - gi\|22124357\|ref\|NP_667780.1\| 5-methyltetrahydropteroyltriglutamate--homocysteine methyltransferase [... gi\|77633875, gi\|... - gi\|77633875\|ref\|ZP_00795989.1\| COG0620: Methionine synthase II (cobalamin-independent) [Yersinia pes... gi\|167401849, gi... - gi\|167401849\|ref\|ZP_02307337.1\| 5-methyltetrahydropteroyltriglutamate--homocysteine S-methyltransfer... gi\|166213623, gi... - gi\|166213623\|ref\|ZP_02239658.1\| 5-methyltetrahydropteroyltriglutamate--homocysteine S-methyltransfer...	0.0	[1..757]	[6..761]
gi\|149289461, gi... - gi\|153997155\|ref\|ZP_02022288.1\| 5-methyltetrahydropteroyltriglutamate-- homocystei ne methyltransfer... gi\|165921840, gi... - gi\|165926316\|ref\|ZP_02222148.1\| 5-methyltetrahydropteroyltriglutamate--homocysteine S-methyltransfer... gi\|165939105, gi... - gi\|165939105\|ref\|ZP_02227656.1\| 5-methyltetrahydropteroyltriglutamate--homocysteine S-methyltransfer... gi\|165989400, gi... - gi\|166011631\|ref\|ZP_02232529.1\| 5-methyltetrahydropteroyltriglutamate--homocysteine S-methyltransfer... gi\|166961025, gi... - gi\|167420896\|ref\|ZP_02312649.1\| 5-methyltetrahydropteroyltriglutamate--homocysteine S-methyltransfer... gi\|229695839, gi... - gi\|229839473\|ref\|ZP_04459632.1\| 5-methyltetrahydropteroyltriglutamate-homocysteine S-methyltransfera... gi\|229686816, gi... - gi\|229900036\|ref\|ZP_04515173.1\| 5-methyltetrahydropteroyltriglutamate-homocysteine S-methyltransfera... gi\|229706057, gi... - gi\|229837114\|ref\|ZP_04457279.1\| 5-methyltetrahydropteroyltriglutamate-homocysteine S-methyltransfera... METE_YERPE - 5-methyltetrahydropteroyltriglutamate--homocysteine methyltransferase OS=Yersinia pestis GN=metE PE=... METE_YERPN - 5-methyltetrahydropteroyltriglutamate--homocysteine methyltransferase OS=Yersinia pestis bv. Antiqua... METE_YERPA - 5-methyltetrahydropteroyltriglutamate--homocysteine methyltransferase OS=Yersinia pestis bv. Antiqua... gi\|45437880, gi\|... - gi\|45443013\|ref\|NP_994552.1\| 5-methyltetrahydropteroyltriglutamate--homocysteine methyltransferase [... gi\|218930790, gi... - gi\|218930790\|ref\|YP_002348665.1\| 5-methyltetrahydropteroyltriglutamate--homocysteine S-methyltransfe...	0.0	[1..757]	[1..756]
gi\|77630686, gi\|... - gi\|77630686\|ref\|ZP_00793272.1\| COG0620: Methionine synthase II (cobalamin-independent) [Yersinia pse...	0.0	[1..757]	[6..761]
METE_YERPS - 5-methyltetrahydropteroyltriglutamate--homocysteine methyltransferase OS=Yersinia pseudotuberculosis... METE_YERPS - 5-methyltetrahydropteroyltriglutamate--homocysteine methyltransferase OS=Yersinia pseudotuberculosis...	0.0	[1..757]	[1..756]
METE_PHOLL - 5-methyltetrahydropteroyltriglutamate--homocysteine methyltransferase OS=Photorhabdus luminescens su... METE_PHOLL - 5-methyltetrahydropteroyltriglutamate--homocysteine methyltransferase OS=Photorhabdus luminescens su...	0.0	[1..759]	[1..758]
gi\|77973685 - gi\|77973685\|ref\|ZP_00829231.1\| COG0620: Methionine synthase II (cobalamin-independent) [Yersinia fre...	0.0	[1..757]	[1..756]
gi\|77957914 - gi\|77957914\|ref\|ZP_00821958.1\| COG0620: Methionine synthase II (cobalamin-independent) [Yersinia ber...	0.0	[1..757]	[3..758]
gi\|194434043, gi... - gi\|83569335\|ref\|ZP_00920790.1\| COG0620: Methionine synthase II (cobalamin-independent) [Shigella dys...	0.0	[1..755]	[1..751]
gi\|75256247, gi\|... - gi\|75256247\|ref\|ZP_00727925.1\| COG0620: Methionine synthase II (cobalamin-independent) [Escherichia ... gi\|193067979, gi... - gi\|75238279\|ref\|ZP_00722278.1\| COG0620: Methionine synthase II (cobalamin-independent) [Escherichia ... gi\|75209544, gi\|... - gi\|75209544\|ref\|ZP_00709765.1\| COG0620: Methionine synthase II (cobalamin-independent) [Escherichia ...	0.0	[1..755]	[1..751]
METE_ECO24 - 5-methyltetrahydropteroyltriglutamate--homocysteine methyltransferase OS=Escherichia coli O139:H28 (...	0.0	[1..755]	[1..751]

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Predicted Domain #1

Region A:
Residues: [1-762]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MAIQTSNLGY PRIGLQREWK KTLEAFWSNK INEEQFLTTM KEIRLQHVKV QQEKGIELIP  60
   61 IGDFTYYDHV LDTAYMLGFI PSRFSEFTSY LDVYFAMARG SKDHVASEMT KWFNTNYHYI 120
  121 VPEYEEGLQI SLKDNRPLRL YEEAKQELGV DGKPVILGPY TFLKLAKGYT QEQFATILKQ 180
  181 LVAPYVQLLS ELHAAGAQII QVDEPIFASL TKEEVQQAKE IYEAIRKEVP NATLLLQTYF 240
  241 DSVEENYEEI ITFPVSSIGL DFVHGKEGNL NAISKYGFPA DKTLAVGCID GRNIWRADLD 300
  301 EVLTLFTTLQ KQVQTKDLIV QPSCSLLHTP IDKTEETHLS TELFDALAFA NQKLEELVLI 360
  361 HSALTQGTES ISNELETYRN VHHTIRSSAA RNREDVKAAR TALKEEDFSR PLPFEKRYEL 420
  421 QQVALKLPLL PTTTIGSFPQ TTEVRQTRKE WRNGIISNEQ YEQFIEKETE KWIRYQEEIG 480
  481 LDVLVHGEFE RTDMVEYFGE RLAGFSFTKN GWVQSYGSRC VKPPVIYGDV AFINGMTIKE 540
  541 TVYAQSLTEK VVKGMLTGPV TILNWSFVRN DIPRKEVSYQ IALALRHEIE LLESSGIRVI 600
  601 QVDEPALREG MPLKEKDWDA YITWAVQSFL LATSSVANET QIHTHMCYSN FEDIVDAIRA 660
  661 LDADVISIET SRSHGEFIDT LKHTTYEKGI GLGVYDIHSP RVPSKDEMYK IVEQSLQVCD 720
  721 PKYFWINPDC GLKTRRTEEV IPALEHMVQA AKDARSLLKT NA

[Run NCBI BLAST on this sequence.]

Detection Method:	PSI-BLAST
Confidence:	1000.0
Match:	1u1hA
Description:	A. thaliana cobalamine independent methionine synthase
Matching Structure (courtesy of the PDB):

Predicted functions:

Term	Confidence	Notes
5-methyltetrahydropteroyltriglutamate-homocysteine S-methyltransferase activity	6.40786073037099	bayes_pls_golite062009
5-methyltetrahydropteroyltri-L-glutamate-dependent methyltransferase activity	6.40786073037099	bayes_pls_golite062009
uroporphyrinogen decarboxylase activity	3.13638443707338	bayes_pls_golite062009
S-methyltransferase activity	3.0142199413027	bayes_pls_golite062009
catalytic activity	2.37862248560593	bayes_pls_golite062009
binding	1.590130518929	bayes_pls_golite062009
carbon-carbon lyase activity	1.54242506764415	bayes_pls_golite062009
carboxy-lyase activity	1.52150758949987	bayes_pls_golite062009
lyase activity	0.825209465219608	bayes_pls_golite062009
protein binding	0.21865699924356	bayes_pls_golite062009

TMHMM	2.0c	PSIPRED	v2.61
SignalP	3.0	COILS	1999
DISOPRED	v0.1	NCBI nr	06/2007
PSI-BLAST	2.2.18	FFAS	ffas03
PDB	06/2007	Pfam	22
HMMER	2.3.2

View Structure Prediction Details

Top Sequence Alignment Hits

Predicted functions: