YRC Public Data Repository - Protein Structure Prediction

Protein:	gi\|30258387, gi\|...
Organism:	Bacillus anthracis str. Ames
Length:	303 amino acids
Reference:	Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16

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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for gi|30258387, gi|....

Description	E-value	Query Range	Subject Range
gi\|42782824, gi\|... - gi\|42782824\|ref\|NP_980071.1\| DNA-3-methyladenine glycosidase [Bacillus cereus ATCC 10987], gi\|427387...	1.0E-71	[1..303]	[1..303]
gi\|52141748, gi\|... - gi\|52141748\|ref\|YP_085081.1\| DNA-3-methyladenine glycosidase [Bacillus cereus E33L], gi\|51975217\|gb\|...	3.0E-70	[1..303]	[1..303]
gi\|49333324, gi\|... - gi\|49481768\|ref\|YP_037807.1\| DNA-3-methyladenine glycosidase [Bacillus thuringiensis serovar konkuki...	9.0E-70	[1..303]	[1..303]
gi\|75759852, gi\|... - gi\|75759852\|ref\|ZP_00739927.1\| DNA-3-methyladenine glycosylase II [Bacillus thuringiensis serovar is...	2.0E-69	[1..303]	[1..303]
gi\|163863624, gi... - gi\|89207782\|ref\|ZP_01186314.1\| DNA-3-methyladenine glycosylase II [Bacillus weihenstephanensis KBAB4...	4.0E-69	[1..303]	[1..303]
gi\|30021836, gi\|... - gi\|30021836\|ref\|NP_833467.1\| DNA-3-methyladenine glycosylase II [Bacillus cereus ATCC 14579], gi\|298...	6.0E-69	[1..303]	[1..303]
gi\|47555062, gi\|... - gi\|47568234\|ref\|ZP_00238937.1\| DNA-3-methyladenine glycosylase II [Bacillus cereus G9241], gi\|475550...	1.0E-68	[1..303]	[1..303]
3MGA_BACSU - DNA-3-methyladenine glycosylase OS=Bacillus subtilis (strain 168) GN=alkA PE=1 SV=1 3MGA_BACSU - DNA-3-methyladenine glycosylase OS=Bacillus subtilis GN=alkA PE=1 SV=1 gi\|221321511 - gi\|221321511\|ref\|ZP_03602805.1\| DNA-3-methyladenine glycosylase [Bacillus subtilis subsp. subtilis s... gi\|221317248 - gi\|221317248\|ref\|ZP_03598542.1\| DNA-3-methyladenine glycosylase [Bacillus subtilis subsp. subtilis s... gi\|221312315 - gi\|221312315\|ref\|ZP_03594120.1\| DNA-3-methyladenine glycosylase [Bacillus subtilis subsp. subtilis s...	3.0E-58	[4..303]	[5..303]
gi\|56911159, gi\|... - gi\|56964916\|ref\|YP_176647.1\| DNA-3-methyladenine glycosylase II [Bacillus clausii KSM-K16], gi\|56911...	8.0E-58	[4..303]	[5..303]
gi\|48764043 - ref\|ZP_00268596.1\| COG0122: 3-methyladenine DNA glycosylase/8-oxoguanine DNA glycosylase [Rhodospiri... gi\|83594686, gi\|... - gi\|83594686\|ref\|YP_428438.1\| transcriptional regulator Ada / DNA-3-methyladenine glycosylase II / DN...	8.0E-54	[8..299]	[204..483]

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Predicted Domain #1

Region A:
Residues: [1-303]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MTAEYSNALI LTVPTEFSFQ ENLRYLSRSN NECMFHIEDN KIYKVIPVHD VKPLVEISMN  60
   61 ADDTIQIRFL GEAYISAKPI RDAVANYVTE WFDLTIDLAP FYTLAKHDVL LQRPIEQYYG 120
  121 LRTLGIPDLF EALSWGIIGQ QINLTYAYTL KRRLVETFGS YVEWNDRKHW IFPSPETIAN 180
  181 LHVEDLKNLK MTTRKCEYLI GIAKLITEGN LSKESLLQIQ DVKQAEKRLT AIHGIGPWTA 240
  241 NYVLMRCLRF PSAFPIDDVG LHNAIKYLTG SESKPTKHEI KDFAVNWKNW ESYATFYLWR 300
  301 VLY

[Run NCBI BLAST on this sequence.]

Detection Method:	PSI-BLAST
Confidence:	50.154902
Match:	1dizA
Description:	3-Methyladenine DNA glycosylase II (gene alkA or aidA)
Matching Structure (courtesy of the PDB):

Predicted functions:

Term	Confidence	Notes
DNA N-glycosylase activity	4.08559331236111	bayes_pls_golite062009
hydrolase activity, hydrolyzing N-glycosyl compounds	3.73234184319832	bayes_pls_golite062009
DNA-(apurinic or apyrimidinic site) lyase activity	3.12421941323765	bayes_pls_golite062009
hydrolase activity, acting on glycosyl bonds	2.54759386266723	bayes_pls_golite062009
catalytic activity	2.50389926428623	bayes_pls_golite062009
oxidized base lesion DNA N-glycosylase activity	1.80199518353554	bayes_pls_golite062009
alkylbase DNA N-glycosylase activity	1.75218522602775	bayes_pls_golite062009
hydrolase activity	1.39000450534744	bayes_pls_golite062009
DNA-3-methyladenine glycosylase I activity	1.14337995879633	bayes_pls_golite062009
oxidized purine base lesion DNA N-glycosylase activity	0.473206156100251	bayes_pls_golite062009
uracil DNA N-glycosylase activity	0.29478804124408	bayes_pls_golite062009
oxidized pyrimidine base lesion DNA N-glycosylase activity	0.253198605718519	bayes_pls_golite062009
RNA polymerase II transcription factor activity	0.0593430405945699	bayes_pls_golite062009
general RNA polymerase II transcription factor activity	0.0274101501785404	bayes_pls_golite062009

TMHMM	2.0c	PSIPRED	v2.61
SignalP	3.0	COILS	1999
DISOPRED	v0.1	NCBI nr	06/2007
PSI-BLAST	2.2.18	FFAS	ffas03
PDB	06/2007	Pfam	22
HMMER	2.3.2

View Structure Prediction Details

Top Sequence Alignment Hits

Predicted functions: