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View Structure Prediction Details

Protein: gi|30258211, gi|...
Organism: Bacillus anthracis str. Ames
Length: 537 amino acids
Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16



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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for gi|30258211, gi|....

Description E-value Query
Range
Subject
Range
gi|56419203, gi|... - gi|56419203|ref|YP_146521.1| acyl-CoA synthetase [Geobacillus kaustophilus HTA426], gi|56379045|dbj|...
0.0 [7..535] [1..514]
gi|77996178, gi|... - gi|78044063|ref|YP_360551.1| long-chain-fatty-acid--CoA ligase [Carboxydothermus hydrogenoformans Z-...
0.0 [3..537] [22..544]
gi|106772735, gi... - gi|148656221|ref|YP_001276426.1| AMP-dependent synthetase and ligase [Roseiflexus sp. RS-1], gi|1485...
0.0 [5..533] [1..511]
gi|55981432, gi|... - gi|55981432|ref|YP_144729.1| long-chain-fatty-acid--CoA ligase [Thermus thermophilus HB8], gi|557728...
0.0 [8..532] [27..557]
gi|52079510, gi|... - gi|52784875|ref|YP_090704.1| acyl-CoA synthetase [Bacillus licheniformis ATCC 14580], gi|52347377|gb...
0.0 [7..530] [1..509]
gi|2633363, gi|1... - gi|2633363|emb|CAB12867.1| yhfL [Bacillus subtilis subsp. subtilis str. 168], gi|16078091|ref|NP_388...
gi|7437856, gi|2... - gi|81668895|sp|O07610.1|LCFB_BACSU RecName: Full=Long-chain-fatty-acid--CoA ligase; AltName: Full=Lo...
0.0 [7..530] [1..511]
gi|53763480, gi|... - gi|75910191|ref|YP_324487.1| AMP-dependent synthetase and ligase [Anabaena variabilis ATCC 29413], g...
0.0 [7..529] [1..496]

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Predicted Domain #1
Region A:
Residues: [1-537]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MMMNVPLTIS SMMERAEKLF SKKEIVSRTH DTVTTLTYKQ LGERTRRLSS ALKKLGIKEG  60
   61 ERIGTLAWNH HRHVEAYFAI PGIASVLHTI NIRLSPQHIS YIIQHAEDRI LLIDEDLVPL 120
  121 IENIQSQLST VQAYIIMTDK DEIPNTTLEP IYHYEKLLEE GDPNFQFVKD IDENTPAGMC 180
  181 YTSATTGNPK GVVYTHRSTV LHCMALGLAD TAALSESDAA MAIVPMFHVN AWGLPFAATW 240
  241 FGSKQVLPGP MFTPKILLEM IQAEKVTLAA GVPTIWLGVL QELENNSYDL SSMTRILCGG 300
  301 AAAPKSVIKA FEQKHNVPFI HAYGMTETSP LVTLARLKSY ETELSYEEQL EIRSKQGYLV 360
  361 PGVEMKVVGT NGEVKWDSTE MGELCLRAPW IAESYYNDDR TVEGFRDGWL YTGDVVTVDE 420
  421 EGCVKIVDRT KDVIKSGGEW ISSVDLENAL MAHDAIFEAA VVAVPHPQWQ ERPVACVVQK 480
  481 KNSTVTKEEI YEFLKPQFAK WWLPDDIVFM EEIPKTSVGK FLKQALRKEL EHLHKEK

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 114.0
Match: 1ultA
Description: Crystal structure of tt0168 from Thermus thermophilus HB8
Matching Structure (courtesy of the PDB):

Predicted functions:

Term Confidence Notes
ligase activity, forming carbon-sulfur bonds 5.10123876514454 bayes_pls_golite062009
fatty acid ligase activity 4.83067429373059 bayes_pls_golite062009
long-chain fatty acid-CoA ligase activity 4.72692389032116 bayes_pls_golite062009
acetate-CoA ligase activity 4.48129067128523 bayes_pls_golite062009
acid-thiol ligase activity 4.28278725989432 bayes_pls_golite062009
CoA-ligase activity 4.12850865352867 bayes_pls_golite062009
oxidoreductase activity, acting on single donors with incorporation of molecular oxygen, incorporation of one atom of oxygen (internal monooxygenases or internal mixed function oxidases) 2.74744781333102 bayes_pls_golite062009
Photinus-luciferin 4-monooxygenase (ATP-hydrolyzing) activity 2.74744781333102 bayes_pls_golite062009
luciferin monooxygenase activity 2.67396462766343 bayes_pls_golite062009
ligase activity 2.49556073715112 bayes_pls_golite062009
transcription regulator activity 2.31193176808353 bayes_pls_golite062009
catalytic activity 1.83545185797733 bayes_pls_golite062009
binding 1.5312519256537 bayes_pls_golite062009
transcription repressor activity 1.2638869228049 bayes_pls_golite062009
transferase activity, transferring acyl groups 0.464663038956639 bayes_pls_golite062009

YRC Informatics Platform - Version 3.0
Created and Maintained by: Michael Riffle