YRC Public Data Repository - Protein Structure Prediction

Protein:	gi\|30263450, gi\|...
Organism:	Bacillus anthracis str. Ames
Length:	377 amino acids
Reference:	Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16

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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for gi|30263450, gi|....

Description	E-value	Query Range	Subject Range
gi\|49479259, gi\|... - gi\|49479259\|ref\|YP_037586.1\| beta-lactamase [Bacillus thuringiensis serovar konkukian str. 97-27], g...	3.0E-96	[1..377]	[1..377]
gi\|51975504, gi\|... - gi\|52142035\|ref\|YP_084794.1\| beta-lactamase [Bacillus cereus E33L], gi\|51975504\|gb\|AAU17054.1\| possi...	6.0E-95	[1..377]	[1..377]
gi\|47558774, gi\|... - gi\|47564622\|ref\|ZP_00235667.1\| beta-lactamase [Bacillus cereus G9241], gi\|47558774\|gb\|EAL17097.1\| be...	8.0E-95	[1..374]	[1..374]
gi\|42782558, gi\|... - gi\|42782558\|ref\|NP_979805.1\| penicillin-binding protein, putative [Bacillus cereus ATCC 10987], gi\|4...	1.0E-94	[1..374]	[1..374]
gi\|89155474, gi\|... - gi\|89206593\|ref\|ZP_01185149.1\| Beta-lactamase [Bacillus weihenstephanensis KBAB4], gi\|89155474\|gb\|EA...	2.0E-91	[1..374]	[1..374]
gi\|29897148, gi\|... - gi\|30021593\|ref\|NP_833224.1\| penicillin-binding protein [Bacillus cereus ATCC 14579], gi\|29897148\|gb... gi\|228654646, gi... - gi\|229128758\|ref\|ZP_04257735.1\| Beta-lactamase [Bacillus cereus BDRD-Cer4], gi\|228654646\|gb\|EEL10507... gi\|228786175, gi... - gi\|228973480\|ref\|ZP_04134064.1\| Beta-lactamase [Bacillus thuringiensis serovar thuringiensis str. T0... gi\|228819068, gi... - gi\|228940562\|ref\|ZP_04103128.1\| Beta-lactamase [Bacillus thuringiensis serovar berliner ATCC 10792],...	4.0E-91	[1..374]	[1..374]
gi\|89202886, gi\|... - gi\|89202886\|ref\|ZP_01181591.1\| Beta-lactamase [Bacillus cereus subsp. cytotoxis NVH 391-98], gi\|8914...	2.0E-81	[1..376]	[1..376]
gi\|22213623 - gi\|22213623\|gb\|AAM93471.1\| beta-lactamase; AmpC [Citrobacter freundii]	1.0E-78	[1..365]	[1..375]

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Predicted Domain #1

Region A:
Residues: [1-377]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MLKKWLIVFF IFAVFSGSVV ALIHASKGKK YDIKAFSNLN NKQKHDMQEV DANEKKHYEV  60
   61 VAGKLDQYLK DKGFNGSVLV ASKDHVILRK GYGYANMKDK VFTTPRTKYR IGSITKTVVA 120
  121 ISIMQLKEKG KLNIEDNVNK YIPSFPADKN ITLRNLLTHT SGLPDQGKGR VDAASRLKLV 180
  181 TWIGSQALQF PAGTGWKYTD YNYMVLAYIV EKITNKPLAE YVKENIFTPV EMHESGMGAT 240
  241 LPEDIFLAEG YTRKDNELIA APRLKMNWLY GCGEMYTTVE DMKRLDEAIM NGKLLSKQSV 300
  301 LDMFTASPAR KYGFSFYTYP DYYHNHGVLA GWNTFNNFNW DKKTFVILFS NVQNGMNDTF 360
  361 NQEFRKMAND LIEGNGA

[Run NCBI BLAST on this sequence.]

Detection Method:	PSI-BLAST
Confidence:	76.09691
Match:	1rgyA
Description:	Citrobacter freundii GN346 Class C beta-Lactamase Complexed with Transition-State Analog of Cefotaxime
Matching Structure (courtesy of the PDB):

Predicted functions:

Term	Confidence	Notes
serine-type D-Ala-D-Ala carboxypeptidase activity	3.37745387761459	bayes_pls_golite062009
penicillin binding	3.16077730467133	bayes_pls_golite062009
serine-type carboxypeptidase activity	3.02516915958448	bayes_pls_golite062009
serine-type exopeptidase activity	2.98959517344587	bayes_pls_golite062009
carboxypeptidase activity	2.34154596924818	bayes_pls_golite062009
catalytic activity	2.2253600206851	bayes_pls_golite062009
drug binding	2.00354593744547	bayes_pls_golite062009
exopeptidase activity	1.66768404710194	bayes_pls_golite062009
peptidase activity	0.0621279448114327	bayes_pls_golite062009

TMHMM	2.0c	PSIPRED	v2.61
SignalP	3.0	COILS	1999
DISOPRED	v0.1	NCBI nr	06/2007
PSI-BLAST	2.2.18	FFAS	ffas03
PDB	06/2007	Pfam	22
HMMER	2.3.2

View Structure Prediction Details

Top Sequence Alignment Hits

Predicted functions: