YRC Public Data Repository - Protein Structure Prediction

Protein:	gi\|30263339, gi\|...
Organism:	Bacillus anthracis str. Ames
Length:	674 amino acids
Reference:	Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16

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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for gi|30263339, gi|....

Description	E-value	Query Range	Subject Range
gi\|42782768, gi\|... - gi\|42782768\|ref\|NP_980015.1\| transketolase [Bacillus cereus ATCC 10987], gi\|42738695\|gb\|AAS42623.1\| ...	0.0	[1..672]	[1..666]
gi\|30021779, gi\|... - gi\|30021779\|ref\|NP_833410.1\| transketolase [Bacillus cereus ATCC 14579], gi\|29897335\|gb\|AAP10611.1\| ... gi\|228723990, gi... - gi\|229047365\|ref\|ZP_04192963.1\| Transketolase [Bacillus cereus AH676], gi\|228723990\|gb\|EEL75337.1\| T... gi\|228959871, gi... - gi\|228959871\|ref\|ZP_04121544.1\| Transketolase [Bacillus thuringiensis serovar pakistani str. T13001]... gi\|228631583, gi... - gi\|229151878\|ref\|ZP_04280076.1\| Transketolase [Bacillus cereus m1550], gi\|228631583\|gb\|EEK88214.1\| T... gi\|228637307, gi... - gi\|229146248\|ref\|ZP_04274623.1\| Transketolase [Bacillus cereus BDRD-ST24], gi\|228637307\|gb\|EEK93762.... gi\|206736052, gi... - gi\|206969011\|ref\|ZP_03229966.1\| transketolase [Bacillus cereus AH1134], gi\|206736052\|gb\|EDZ53210.1\| ... gi\|228654500, gi... - gi\|229128955\|ref\|ZP_04257930.1\| Transketolase [Bacillus cereus BDRD-Cer4], gi\|228654500\|gb\|EEL10363....	0.0	[1..672]	[15..680]
gi\|47554080, gi\|... - gi\|47569206\|ref\|ZP_00239892.1\| transketolase [Bacillus cereus G9241], gi\|47554080\|gb\|EAL12445.1\| tra...	0.0	[1..672]	[1..666]
gi\|163941287, gi... - gi\|89209315\|ref\|ZP_01187752.1\| transketolase [Bacillus weihenstephanensis KBAB4], gi\|89152757\|gb\|EAR... gi\|229134484, gi... - gi\|229134484\|ref\|ZP_04263297.1\| Transketolase [Bacillus cereus BDRD-ST196], gi\|228649105\|gb\|EEL05127...	0.0	[1..672]	[1..666]
TKT_HAEIN - Transketolase OS=Haemophilus influenzae GN=tktA PE=3 SV=1 TKT_HAEIN - Transketolase OS=Haemophilus influenzae (strain ATCC 51907 / DSM 11121 / KW20 / Rd) GN=tktA PE=3 SV=...	0.0	[7..672]	[5..665]
gi\|20515171, gi\|... - gi\|20806716\|ref\|NP_621887.1\| transketolase [Thermoanaerobacter tengcongensis MB4], gi\|20515171\|gb\|AA... gi\|20806716 - gi\|20806716\|ref\|NP_621887.1\| Transketolase [Thermoanaerobacter tengcongensis MB4]	0.0	[1..672]	[1..665]
gi\|51975328, gi\|... - gi\|52141859\|ref\|YP_084972.1\| transketolase [Bacillus cereus E33L], gi\|51975328\|gb\|AAU16878.1\| transk... gi\|222097146, gi... - gi\|222097146\|ref\|YP_002531203.1\| transketolase [Bacillus cereus Q1], gi\|221241204\|gb\|ACM13914.1\| tra... gi\|217065730, gi... - gi\|217961116\|ref\|YP_002339684.1\| transketolase [Bacillus cereus AH187], gi\|217065730\|gb\|ACJ79980.1\| ...	0.0	[1..672]	[1..666]
gi\|46133244 - gi\|46133244\|ref\|ZP_00156879.2\| COG0021: Transketolase [Haemophilus influenzae R2866]	0.0	[7..672]	[20..680]
gi\|49478325, gi\|... - gi\|49478325\|ref\|YP_037757.1\| transketolase [Bacillus thuringiensis serovar konkukian str. 97-27], gi...	0.0	[1..672]	[1..666]
gi\|49186473, gi\|... - gi\|49186473\|ref\|YP_029725.1\| transketolase [Bacillus anthracis str. Sterne], gi\|49180400\|gb\|AAT55776... gi\|170709286, gi... - gi\|170709286\|ref\|ZP_02899704.1\| transketolase [Bacillus anthracis str. A0389], gi\|170125795\|gb\|EDS94... gi\|47504182, gi\|... - gi\|47529034\|ref\|YP_020383.1\| transketolase [Bacillus anthracis str. 'Ames Ancestor'], gi\|47504182\|gb... gi\|167510057, gi... - gi\|167641964\|ref\|ZP_02400198.1\| transketolase [Bacillus anthracis str. A0193], gi\|167510057\|gb\|EDR85... gi\|30258263, gi\|... - gi\|30263628\|ref\|NP_846005.1\| transketolase [Bacillus anthracis str. Ames], gi\|30258263\|gb\|AAP27491.1... gi\|254733645 - gi\|254733645\|ref\|ZP_05191361.1\| transketolase [Bacillus anthracis str. Western North America USA6153...	0.0	[1..672]	[1..666]

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Predicted Domain #1

Region A:
Residues: [1-674]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MTQNINQLAV NTIRTLSIDA INAANSGHPG LPMGAAPMAY ALWANHLNHN PNHPKWFNRD  60
   61 RFVLSAGHGS SLLYSLLHLA GYDVSIDDLK NFRKLNSKTP GHPEFGHTSG VEATTGPLGQ 120
  121 GIANAVGMAM AEAHLAAKFN KDGHSIIDHN TYALVGDGDL MEGVAYEAMS MEGVAYEAMS 180
  181 MAGHMKLGKL IVLYDSNEIS LDGELNIAFS EDMQKRVESA HWQYVRVEDG NDVDAITKAI 240
  241 QLAKDNTDQP TLIEIRTVIG YGSPKVAGTN KAHGNPLGLE EATATKQVYG WHYEEDFFVP 300
  301 EEVTAHFNEL KQKGIEKERG WNEQFNLYRE SNPALADELE KAIIGEVLIE AKDILSFDSE 360
  361 KTISTRVASG EAINHYVKSI PSIFGGSADL SHSTMTDIKG EAVYAVESYA GRNIYFGVRE 420
  421 HAMGAAANGL ALHGGVKPFV STFFVFNDYL RPSIRLAALQ KLPVTYVFTH DSIAVGEDGP 480
  481 THEPIEHLAA LRAIPGLTVI RPSDANETAS AWAYALQQTE GPVVLVLSRQ NLPVFHETKA 540
  541 NIENLSKGAY VLTQTNENPD VILIATGSEV SLAASAKAKL EEDNVSVRIV AMPSWELFDR 600
  601 QSKEYKESVL PSSVTKRVSL EMGVSLGWER YVGQEGNILS IETFGASGTG AEVMNLFGFT 660
  661 TENVVQITKN VLNS

[Run NCBI BLAST on this sequence.]

Detection Method:	PSI-BLAST
Confidence:	170.0
Match:	1qgdA
Description:	Transketolase (TK), Pyr module; Transketolase (TK), PP module; Transketolase (TK), C-domain
Matching Structure (courtesy of the PDB):

Predicted functions:

Term	Confidence	Notes
transketolase activity	6.17852985073866	bayes_pls_golite062009
oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor	2.93250853993668	bayes_pls_golite062009
pyruvate dehydrogenase activity	2.81702263447118	bayes_pls_golite062009
pyruvate dehydrogenase (acetyl-transferring) activity	2.6977837113283	bayes_pls_golite062009
transferase activity, transferring aldehyde or ketonic groups	2.21959520697519	bayes_pls_golite062009
binding	0.980920092099572	bayes_pls_golite062009
catalytic activity	0.545407789079971	bayes_pls_golite062009
thiamin pyrophosphate binding	0.297191393111081	bayes_pls_golite062009
acetolactate synthase activity	0.173822256668691	bayes_pls_golite062009

TMHMM	2.0c	PSIPRED	v2.61
SignalP	3.0	COILS	1999
DISOPRED	v0.1	NCBI nr	06/2007
PSI-BLAST	2.2.18	FFAS	ffas03
PDB	06/2007	Pfam	22
HMMER	2.3.2

View Structure Prediction Details

Top Sequence Alignment Hits

Predicted functions: