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View Structure Prediction Details

Protein: gi|30262375, gi|...
Organism: Bacillus anthracis str. Ames
Length: 538 amino acids
Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16



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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for gi|30262375, gi|....

Description E-value Query
Range
Subject
Range
gi|77996178, gi|... - gi|78044063|ref|YP_360551.1| long-chain-fatty-acid--CoA ligase [Carboxydothermus hydrogenoformans Z-...
0.0 [6..535] [8..545]
gi|75701558, gi|... - gi|75907833|ref|YP_322129.1| amino acid adenylation [Anabaena variabilis ATCC 29413], gi|75701558|gb...
0.0 [1..531] [520..1044]
gi|56419203, gi|... - gi|56419203|ref|YP_146521.1| acyl-CoA synthetase [Geobacillus kaustophilus HTA426], gi|56379045|dbj|...
0.0 [25..531] [1..511]
gi|27817222 - gi|27817222|gb|AAO23333.1| NcpA [Nostoc sp. ATCC 53789]
0.0 [1..530] [2642..3174]
gi|55981432, gi|... - gi|55981432|ref|YP_144729.1| long-chain-fatty-acid--CoA ligase [Thermus thermophilus HB8], gi|557728...
0.0 [5..533] [6..559]
gi|51891757, gi|... - gi|51891757|ref|YP_074448.1| long-chain fatty-acid-CoA ligase [Symbiobacterium thermophilum IAM 1486...
0.0 [5..535] [13..560]
gi|186682529, gi... - gi|23129063|ref|ZP_00110897.1| COG1020: Non-ribosomal peptide synthetase modules and related protein...
0.0 [1..529] [1545..2064]
gi|49610952, gi|... - gi|50120426|ref|YP_049593.1| non-ribosomal peptide synthetase [Pectobacterium atrosepticum SCRI1043]...
0.0 [1..535] [5805..6332]

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Predicted Domain #1
Region A:
Residues: [1-538]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MLTGYTKWPK EFADRYREEG CWLGETFGGV LRERAEKYGD QIAVVSGNTY ITYSELDKKV  60
   61 DRLASGLLNL GIKPEDRVVI QLPNVIEFFE MCFALFRIGA LPVFALPSHR SSEISYFCEF 120
  121 GEASAYVISD KALGFDYRKL AREVKEKVPT LQHVIVVGEK EEFVNISDLY IDPVLLPEVQ 180
  181 PSDVAFLQLS GGTTGLSKLI PRTHDDYIYS LRVSAEICNL SAESVYMAVL PVAHNYPMSS 240
  241 PGTFGTFYAG GKVVLATGGS PDEAFALIEK EKVTITALVP PLAMIWLDAA SSRNNDLSSL 300
  301 EVIQVGGAKF SAEVAKRIRP TFGCTLQQVF GMAEGLVNYT RLDDPEEIII HTQGRPMSAL 360
  361 DEVRVVDEYD NDVKPGEVGS LLTRGPYTIR GYYKAEEHNA RSFTNDGFYR TGDLVKVNEQ 420
  421 GYIIVEGRDK DQINRGGEKV AAEEVENHLL AHDAVHDVAI VSMPDDYLGE RTCAFVIARG 480
  481 QAPAVSELKR FLRERGIAAY KIPDRIEFIE SFPQTGVGKV SKKELRKVIA EKLVTVKR

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 125.0
Match: 1md9A
Description: Dihydroxybenzoate-AMP ligase DhbE
Matching Structure (courtesy of the PDB):

Predicted functions:

Term Confidence Notes
ligase activity, forming carbon-sulfur bonds 5.10123876514454 bayes_pls_golite062009
fatty acid ligase activity 4.83067429373059 bayes_pls_golite062009
long-chain fatty acid-CoA ligase activity 4.72692389032116 bayes_pls_golite062009
acetate-CoA ligase activity 4.48129067128523 bayes_pls_golite062009
acid-thiol ligase activity 4.28278725989432 bayes_pls_golite062009
CoA-ligase activity 4.12850865352867 bayes_pls_golite062009
oxidoreductase activity, acting on single donors with incorporation of molecular oxygen, incorporation of one atom of oxygen (internal monooxygenases or internal mixed function oxidases) 2.74744781333102 bayes_pls_golite062009
Photinus-luciferin 4-monooxygenase (ATP-hydrolyzing) activity 2.74744781333102 bayes_pls_golite062009
luciferin monooxygenase activity 2.67396462766343 bayes_pls_golite062009
ligase activity 2.49556073715112 bayes_pls_golite062009
transcription regulator activity 2.31193176808353 bayes_pls_golite062009
catalytic activity 1.83545185797733 bayes_pls_golite062009
binding 1.5312519256537 bayes_pls_golite062009
transcription repressor activity 1.2638869228049 bayes_pls_golite062009

YRC Informatics Platform - Version 3.0
Created and Maintained by: Michael Riffle