YRC Public Data Repository - Protein Structure Prediction

Protein:	gi\|30261633, gi\|...
Organism:	Bacillus anthracis str. Ames
Length:	326 amino acids
Reference:	Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16

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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for gi|30261633, gi|....

Description	E-value	Query Range	Subject Range
gi\|42780740, gi\|... - gi\|42780740\|ref\|NP_977987.1\| birA bifunctional protein [Bacillus cereus ATCC 10987], gi\|42736660\|gb\|...	8.0E-96	[1..326]	[1..326]
gi\|49332554, gi\|... - gi\|49480998\|ref\|YP_035753.1\| biotin operon repressor [Bacillus thuringiensis serovar konkukian str. ...	1.0E-95	[1..326]	[1..326]
gi\|51977280, gi\|... - gi\|52143811\|ref\|YP_083017.1\| biotin operon repressor [Bacillus cereus E33L], gi\|51977280\|gb\|AAU18830...	5.0E-95	[1..326]	[1..326]
gi\|74492116, gi\|... - gi\|75760405\|ref\|ZP_00740449.1\| Biotin operon repressor / Biotin--[acetyl-CoA-carboxylase] synthetase...	1.0E-94	[1..326]	[5..330]
gi\|89200996, gi\|... - gi\|89200996\|ref\|ZP_01179744.1\| Biotin--acetyl-CoA-carboxylase ligase [Bacillus cereus subsp. cytotox...	1.0E-94	[1..325]	[1..325]
gi\|163939454, gi... - gi\|89204925\|ref\|ZP_01183500.1\| Biotin--acetyl-CoA-carboxylase ligase [Bacillus weihenstephanensis KB...	8.0E-94	[1..326]	[1..326]
gi\|29895229, gi\|... - gi\|30019685\|ref\|NP_831316.1\| biotin operon repressor / biotin--[acetyl-CoA-carboxylase] synthetase [...	2.0E-92	[11..326]	[2..317]
gi\|56380557, gi\|... - gi\|56420715\|ref\|YP_148033.1\| biotin [acetyl-CoA carboxylase] synthetase; transcriptional repressor o...	4.0E-92	[2..323]	[6..327]
BIRA_BACSU - Bifunctional protein BirA OS=Bacillus subtilis GN=birA PE=1 SV=1 BIRA_BACSU - Bifunctional ligase/repressor BirA OS=Bacillus subtilis (strain 168) GN=birA PE=1 SV=1 gi\|221323680 - gi\|221323680\|ref\|ZP_03604974.1\| transcriptional regulator and biotin acetyl-CoA-carboxylase syntheta... gi\|221319404 - gi\|221319404\|ref\|ZP_03600698.1\| transcriptional regulator and biotin acetyl-CoA-carboxylase syntheta... gi\|221314482 - gi\|221314482\|ref\|ZP_03596287.1\| transcriptional regulator and biotin acetyl-CoA-carboxylase syntheta...	6.0E-92	[1..325]	[1..324]
gi\|52080752, gi\|... - gi\|52786123\|ref\|YP_091952.1\| hypothetical protein BLi02379 [Bacillus licheniformis ATCC 14580], gi\|5...	8.0E-92	[1..325]	[1..324]

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Predicted Domain #1

Region A:
Residues: [1-326]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MQSTIRKQLL QVFSEADGEF VSGQTISDKL GCSRTAVWKH MEDLRNEGYE LEAVRRLGYR  60
   61 IASKPDKVTA NEIQLGLQTK HIGRTVYFEE SVESTQHIAA KLAYEGAEEG TIVVAEEQTA 120
  121 GRGRLSRKWH SPKGTGIWMS IILRPSIPVH HAPQLTLLAA VSVAQAIEKC TGVNVGIKWP 180
  181 NDILIQGKKA VGILTEMQAD PDKINAVIMG IGINANQKQE HFDEEIQHIA TSLAIESGKP 240
  241 IVRAELMQQI FLQLEKLYEE YLQNGFSVIK ILWESYAVSI GKEINARTMR ETITGVAKGI 300
  301 TEDGVLLLED HEGKVHHIHS ADIEIK

[Run NCBI BLAST on this sequence.]

Detection Method:	PSI-BLAST
Confidence:	78.69897
Match:	1biaA
Description:	THE E. COLI BIOTIN HOLOENZYME SYNTHETASE(SLASH)BIO REPRESSOR CRYSTAL STRUCTURE DELINEATES THE BIOTIN AND DNA-BINDING DOMAINS
Matching Structure (courtesy of the PDB):

Predicted functions:

Term	Confidence	Notes
ligase activity, forming carbon-oxygen bonds	3.33073922220594	bayes_pls_golite062009
ligase activity, forming aminoacyl-tRNA and related compounds	3.33073922220594	bayes_pls_golite062009
aminoacyl-tRNA ligase activity	3.33034630936933	bayes_pls_golite062009
ligase activity	3.05852492533937	bayes_pls_golite062009
catalytic activity	2.36416267096403	bayes_pls_golite062009
biotin-[acetyl-CoA-carboxylase] ligase activity	1.84290209862678	bayes_pls_golite062009
biotin-protein ligase activity	1.84290209862678	bayes_pls_golite062009
transcription activator activity	0.53294679084865	bayes_pls_golite062009
sequence-specific DNA binding	0.53285802828572	bayes_pls_golite062009
transcription regulator activity	0.514652697234715	bayes_pls_golite062009
nucleic acid binding	0.268902262140417	bayes_pls_golite062009
binding	0.204413263196103	bayes_pls_golite062009
DNA binding	0.114801541522161	bayes_pls_golite062009

TMHMM	2.0c	PSIPRED	v2.61
SignalP	3.0	COILS	1999
DISOPRED	v0.1	NCBI nr	06/2007
PSI-BLAST	2.2.18	FFAS	ffas03
PDB	06/2007	Pfam	22
HMMER	2.3.2

View Structure Prediction Details

Top Sequence Alignment Hits

Predicted functions: