YRC Public Data Repository - Protein Structure Prediction

Protein:	gi\|30255200, gi\|...
Organism:	Bacillus anthracis str. Ames
Length:	253 amino acids
Reference:	Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16

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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for gi|30255200, gi|....

Description	E-value	Query Range	Subject Range
gi\|74488931, gi\|... - gi\|75763581\|ref\|ZP_00743282.1\| Indole-3-glycerol phosphate synthase [Bacillus thuringiensis serovar ... gi\|228964290, gi... - gi\|228964290\|ref\|ZP_04125409.1\| Indole-3-glycerol phosphate synthase [Bacillus thuringiensis serovar... gi\|228899922, gi... - gi\|228899922\|ref\|ZP_04064163.1\| Indole-3-glycerol phosphate synthase [Bacillus thuringiensis IBL 422... TRPC_BACC2 - Indole-3-glycerol phosphate synthase OS=Bacillus cereus (strain G9842) GN=trpC PE=3 SV=1	1.0E-54	[1..253]	[1..253]
TRPC_BACWK - Indole-3-glycerol phosphate synthase OS=Bacillus weihenstephanensis (strain KBAB4) GN=trpC PE=3 SV=1 gi\|229010633, gi... - gi\|229010633\|ref\|ZP_04167833.1\| Indole-3-glycerol phosphate synthase [Bacillus mycoides DSM 2048], g...	2.0E-54	[1..253]	[1..253]
gi\|196035372, gi... - gi\|196035372\|ref\|ZP_03102777.1\| indole-3-glycerol phosphate synthase [Bacillus cereus W], gi\|1959920... gi\|228662524, gi... - gi\|229120864\|ref\|ZP_04250106.1\| Indole-3-glycerol phosphate synthase [Bacillus cereus 95/8201], gi\|2... TRPC_BACHK - Indole-3-glycerol phosphate synthase OS=Bacillus thuringiensis subsp. konkukian (strain 97-27) GN=tr... TRPC_BACHK - Indole-3-glycerol phosphate synthase OS=Bacillus thuringiensis subsp. konkukian GN=trpC PE=3 SV=1 gi\|228693066, gi... - gi\|229090286\|ref\|ZP_04221531.1\| Indole-3-glycerol phosphate synthase [Bacillus cereus Rock3-42], gi\|... gi\|228926379, gi... - gi\|228926379\|ref\|ZP_04089451.1\| Indole-3-glycerol phosphate synthase [Bacillus thuringiensis serovar...	4.0E-54	[1..253]	[1..253]
TRPC_BACCZ - Indole-3-glycerol phosphate synthase OS=Bacillus cereus (strain ZK / E33L) GN=trpC PE=3 SV=1	1.0E-53	[1..253]	[1..253]
TRPC_BACCR - Indole-3-glycerol phosphate synthase OS=Bacillus cereus (strain ATCC 14579 / DSM 31 / JCM 2152 / NBR... gi\|228957616, gi... - gi\|228957616\|ref\|ZP_04119366.1\| Indole-3-glycerol phosphate synthase [Bacillus thuringiensis serovar... gi\|229126650, gi... - gi\|229126650\|ref\|ZP_04255662.1\| Indole-3-glycerol phosphate synthase [Bacillus cereus BDRD-Cer4], gi...	3.0E-53	[1..253]	[1..253]
gi\|66044011, gi\|... - gi\|66044011\|ref\|YP_233852.1\| indole-3-glycerol-phosphate synthase [Pseudomonas syringae pv. syringae...	4.0E-53	[1..252]	[1..263]
gi\|7428356 - pir\|\|S76016 hypothetical protein - Synechocystis sp. (strain PCC 6803) TRPC_SYNY3 - Indole-3-glycerol phosphate synthase OS=Synechocystis sp. (strain ATCC 27184 / PCC 6803 / N-1) GN=tr... TRPC_SYNY3 - Indole-3-glycerol phosphate synthase OS=Synechocystis sp. (strain PCC 6803 / Kazusa) GN=trpC PE=3 SV...	5.0E-53	[4..253]	[31..295]
gi\|17129758, gi\|... - gi\|17227909\|ref\|NP_484457.1\| indole-3-glycerol-phosphate synthase [Nostoc sp. PCC 7120], gi\|17129758... gi\|25291425 - pir\|\|AD1858 indole-3-glycerol phosphate synthase [imported] - Nostoc sp. (strain PCC 7120)	5.0E-52	[4..252]	[27..290]
gi\|186464185, gi... - gi\|23128272\|ref\|ZP_00110123.1\| COG0134: Indole-3-glycerol phosphate synthase [Nostoc punctiforme PCC...	6.0E-52	[4..250]	[11..272]
gi\|47569172, gi\|... - gi\|47569172\|ref\|ZP_00239859.1\| indole-3-glycerol phosphate synthase [Bacillus cereus G9241], gi\|4755...	1.0E-51	[1..253]	[1..253]

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Predicted Domain #1

Region A:
Residues: [1-253]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MGTILDKIVN QKKKEVAALY ETYTPVKEKR KTRSLVKALE QFTVIAEVKR ASPSKGDINL  60
   61 HVDVRKQVKT YEECGAGAVS VLTDGQFFKG SFYDLQTARE ESSIPLLCKD FIIDKIQIDR 120
  121 AYEAGADIIL LIVAALTKEK LKELYSYVLE KGLEAIVEVH DEQELEIAIQ LNPHVIGINN 180
  181 RNLKTFEVDL SQTEKLGKRL NEEKLLWISE SGIHSKEDII RVKRAGAKGV LVGEALMTSS 240
  241 SIHTFFEDCK VNI

[Run NCBI BLAST on this sequence.]

Detection Method:	PSI-BLAST
Confidence:	48.69897
Match:	1piiA
Description:	THREE-DIMENSIONAL STRUCTURE OF THE BIFUNCTIONAL ENZYME PHOSPHORIBOSYLANTHRANILATE ISOMERASE: INDOLEGLYCEROLPHOSPHATE SYNTHASE FROM ESCHERICHIA COLI REFINED AT 2.0 ANGSTROMS RESOLUTION
Matching Structure (courtesy of the PDB):

Predicted functions:

Term	Confidence	Notes
tryptophan synthase activity	3.15663465352598	bayes_pls_golite062009
indole-3-glycerol-phosphate synthase activity	3.12120866545322	bayes_pls_golite062009
catalytic activity	2.81275055404078	bayes_pls_golite062009
phosphoribosylanthranilate isomerase activity	2.655130814615	bayes_pls_golite062009
carbon-carbon lyase activity	2.44001937916931	bayes_pls_golite062009
carboxy-lyase activity	1.80978905789979	bayes_pls_golite062009
lyase activity	0.9228652996943	bayes_pls_golite062009
imidazoleglycerol-phosphate synthase activity	0.82314869965119	bayes_pls_golite062009
1-(5-phosphoribosyl)-5-[(5-phosphoribosylamino)methylideneamino]imidazole-4-carboxamide isomerase activity	0.302746738903759	bayes_pls_golite062009
isomerase activity	0.14149405165663	bayes_pls_golite062009

TMHMM	2.0c	PSIPRED	v2.61
SignalP	3.0	COILS	1999
DISOPRED	v0.1	NCBI nr	06/2007
PSI-BLAST	2.2.18	FFAS	ffas03
PDB	06/2007	Pfam	22
HMMER	2.3.2

View Structure Prediction Details

Top Sequence Alignment Hits

Predicted functions: