YRC Public Data Repository - Protein Structure Prediction

Protein:	gi\|30261325, gi\|...
Organism:	Bacillus anthracis str. Ames
Length:	322 amino acids
Reference:	Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16

[What does the above image mean?]

[Show Ginzu Version Information]

Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for gi|30261325, gi|....

Description	E-value	Query Range	Subject Range
gi\|41205692 - gi\|41205692\|gb\|AAR99612.1\| dTDP-glucose 4,6-dehydratase [Geobacillus stearothermophilus]	0.0	[1..320]	[3..321]
gi\|33413324, gi\|... - gi\|33413324\|emb\|CAD67949.1\| putative dTDP-glucose 4,6-dehydratase [Thermotoga sp. RQ2], gi\|170288108...	3.0E-99	[1..320]	[1..323]
gi\|56911695, gi\|... - gi\|56965451\|ref\|YP_177183.1\| dTDP glucose 4, 6-dehydratase [Bacillus clausii KSM-K16], gi\|56911695\|d...	6.0E-99	[1..321]	[1..321]
gi\|16357461 - gi\|16357461\|gb\|AAL18013.1\| dTDP-glucose 4,6-dehydratase [Aneurinibacillus thermoaerophilus]	2.0E-97	[1..320]	[1..319]
gi\|7437238 - pir\|\|H69105 dTDP-glucose 4,6-dehydratase - Methanobacterium thermoautotrophicum (strain Delta H) gi\|15679777, gi\|... - gi\|2622920\|gb\|AAB86255.1\| dTDP-glucose 4,6-dehydratase [Methanothermobacter thermautotrophicus str. ...	1.0E-96	[2..321]	[3..318]
gi\|51977585, gi\|... - gi\|52144116\|ref\|YP_082712.1\| dTDP-glucose 4,6-dehydratase [Bacillus cereus E33L], gi\|51977585\|gb\|AAU...	2.0E-95	[1..322]	[1..322]
gi\|224500275 - gi\|224500275\|ref\|ZP_03668624.1\| hypothetical protein LmonF1_11614 [Listeria monocytogenes Finland 19... gi\|47016559, gi\|... - gi\|47094941\|ref\|ZP_00232554.1\| dTDP-glucose 4,6-dehydratase [Listeria monocytogenes str. 1/2a F6854]... gi\|254911768, gi... - gi\|254911768\|ref\|ZP_05261780.1\| hypothetical protein LmonJ2_03150 [Listeria monocytogenes J2818], gi... gi\|254898743, gi... - gi\|254898743\|ref\|ZP_05258667.1\| hypothetical protein LmonJ_02970 [Listeria monocytogenes J0161], gi\|... gi\|254936094, gi... - gi\|254936094\|ref\|ZP_05267791.1\| hypothetical protein LmonF6_03155 [Listeria monocytogenes F6900], gi...	7.0E-95	[1..321]	[1..321]
gi\|42780411, gi\|... - gi\|42780411\|ref\|NP_977658.1\| dTDP-glucose 4,6-dehydratase [Bacillus cereus ATCC 10987], gi\|42736330\|...	8.0E-95	[1..322]	[1..322]

Back

Predicted Domain #1

Region A:
Residues: [1-322]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MNILVTGGAG FIGSNFVHYM LQSYETYKII NFDALTYSGN LNNVKSIQDH PNYYFVKGEI  60
   61 QNGELLEHVI KERDVQVIVN FAAESHVDRS IENPIPFYDT NVIGTVTLLE LVKKYPHIKL 120
  121 VQVSTDEVYG SLGKTGRFTE ETPLAPNSPY SSSKASADMI ALAYYKTYQL PVIVTRCSNN 180
  181 YGPYQYPEKL IPLMVTNALE GKKLPLYGDG LNVRDWLHVT DHCSAIDVVL HKGRVGEVYN 240
  241 IGGNNEKTNV EVVEQIITLL GKTKKDIEYV TDRLGHDRRY AINAEKMKNE FDWEPKYTFE 300
  301 QGLQETVQWY EKNEEWWKPL KK

[Run NCBI BLAST on this sequence.]

Detection Method:	PSI-BLAST
Confidence:	91.30103
Match:	1r66A
Description:	Crystal Structure of DesIV (dTDP-glucose 4,6-dehydratase) from Streptomyces venezuelae with NAD and TYD bound
Matching Structure (courtesy of the PDB):

Predicted functions:

Term	Confidence	Notes
UDP-glucose 4-epimerase activity	2.13934644118967	bayes_pls_golite062009
catalytic activity	1.79741889688267	bayes_pls_golite062009
steroid dehydrogenase activity	1.75109362865449	bayes_pls_golite062009
steroid dehydrogenase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor	1.55012034958204	bayes_pls_golite062009
oxidoreductase activity, acting on CH-OH group of donors	1.03956654822048	bayes_pls_golite062009
nucleic acid binding	0.868888700854563	bayes_pls_golite062009
oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor	0.82673050487418	bayes_pls_golite062009
DNA binding	0.790382977752475	bayes_pls_golite062009
binding	0.784517759335365	bayes_pls_golite062009
transcription regulator activity	0.613310508772122	bayes_pls_golite062009
transcription factor activity	0.11102650759187	bayes_pls_golite062009

TMHMM	2.0c	PSIPRED	v2.61
SignalP	3.0	COILS	1999
DISOPRED	v0.1	NCBI nr	06/2007
PSI-BLAST	2.2.18	FFAS	ffas03
PDB	06/2007	Pfam	22
HMMER	2.3.2

View Structure Prediction Details

Top Sequence Alignment Hits

Predicted functions: