YRC Public Data Repository - Protein Structure Prediction

Protein:	gi\|30254902, gi\|...
Organism:	Bacillus anthracis str. Ames
Length:	329 amino acids
Reference:	Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16

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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for gi|30254902, gi|....

Description	E-value	Query Range	Subject Range
gi\|56419344, gi\|... - gi\|56419344\|ref\|YP_146662.1\| tryptophanyl-tRNA synthetase [Geobacillus kaustophilus HTA426], gi\|5637...	0.0	[1..328]	[1..328]
gi\|28373633, gi\|... - gi\|68506\|pir\|\|YWBSF tryptophan-tRNA ligase (EC 6.1.1.2) - Bacillus stearothermophilus, gi\|28373634\|p...	0.0	[1..328]	[1..328]
gi\|152974707, gi... - gi\|89200609\|ref\|ZP_01179361.1\| Tryptophanyl-tRNA synthetase, class Ib [Bacillus cereus subsp. cytoto...	0.0	[1..329]	[1..329]
gi\|89157657, gi\|... - gi\|89204596\|ref\|ZP_01183173.1\| Tryptophanyl-tRNA synthetase, class Ib [Bacillus weihenstephanensis K...	0.0	[1..329]	[1..329]
gi\|217063119, gi... - gi\|217958758\|ref\|YP_002337306.1\| tryptophanyl-tRNA synthetase [Bacillus cereus AH187], gi\|217063119\|... gi\|229177696, gi... - gi\|229177696\|ref\|ZP_04305071.1\| Tryptophanyl-tRNA synthetase [Bacillus cereus 172560W], gi\|228605751... gi\|206744124, gi... - gi\|206977696\|ref\|ZP_03238588.1\| tryptophanyl-tRNA synthetase [Bacillus cereus H3081.97], gi\|20674412... gi\|228645625, gi... - gi\|229137968\|ref\|ZP_04266567.1\| Tryptophanyl-tRNA synthetase [Bacillus cereus BDRD-ST26], gi\|2286456... gi\|206967927, gi... - gi\|206967927\|ref\|ZP_03228883.1\| tryptophanyl-tRNA synthetase [Bacillus cereus AH1134], gi\|206736847\|... gi\|228704792, gi... - gi\|229078476\|ref\|ZP_04211036.1\| Tryptophanyl-tRNA synthetase [Bacillus cereus Rock4-2], gi\|228704792... gi\|228807947, gi... - gi\|228951662\|ref\|ZP_04113764.1\| Tryptophanyl-tRNA synthetase [Bacillus thuringiensis serovar kurstak... gi\|229195479, gi... - gi\|229195479\|ref\|ZP_04322247.1\| Tryptophanyl-tRNA synthetase [Bacillus cereus m1293], gi\|228588019\|g... gi\|229189370, gi... - gi\|229189370\|ref\|ZP_04316389.1\| Tryptophanyl-tRNA synthetase [Bacillus cereus ATCC 10876], gi\|228594... gi\|42780371, gi\|... - gi\|42780371\|ref\|NP_977618.1\| tryptophanyl-tRNA synthetase [Bacillus cereus ATCC 10987], gi\|42736290\|... gi\|52144152, gi\|... - gi\|52144152\|ref\|YP_082676.1\| tryptophanyl-tRNA synthetase [Bacillus cereus E33L], gi\|51977621\|gb\|AAU... gi\|222094906, gi... - gi\|222094906\|ref\|YP_002528966.1\| tryptophan--tRNA ligase (tryptophanyl-tRNA synthetase) [Bacillus ce...	0.0	[1..329]	[1..329]
gi\|49477116, gi\|... - gi\|49477116\|ref\|YP_035418.1\| tryptophanyl-tRNA synthetase [Bacillus thuringiensis serovar konkukian ...	0.0	[1..329]	[1..329]
gi\|56910543, gi\|... - gi\|56964300\|ref\|YP_176031.1\| tryptophanyl-tRNA synthetase [Bacillus clausii KSM-K16], gi\|56910543\|db...	0.0	[1..329]	[1..329]
SYW_BACHD - Tryptophan--tRNA ligase OS=Bacillus halodurans (strain ATCC BAA-125 / DSM 18197 / FERM 7344 / JCM 91... SYW_BACHD - Tryptophanyl-tRNA synthetase OS=Bacillus halodurans GN=trpS PE=3 SV=1	0.0	[2..329]	[3..330]
SYW_LISMO - Tryptophan--tRNA ligase OS=Listeria monocytogenes GN=trpS PE=3 SV=1 gi\|126942311, gi... - gi\|254899100\|ref\|ZP_05259024.1\| tryptophanyl-tRNA synthetase [Listeria monocytogenes J0161], gi\|1531... gi\|127633510, gi... - gi\|254831365\|ref\|ZP_05236020.1\| tryptophanyl-tRNA synthetase [Listeria monocytogenes 10403S], gi\|153... gi\|254872667 - gi\|254872667\|ref\|ZP_05245377.1\| tryptophanyl-tRNA synthetase [Listeria monocytogenes FSL N1-017] gi\|133729382, gi... - gi\|254826913\|ref\|ZP_05231600.1\| tryptophanyl-tRNA synthetase [Listeria monocytogenes FSL N3-165], gi... gi\|254912759 - gi\|254912759\|ref\|ZP_05262771.1\| tryptophanyl-tRNA synthetase [Listeria monocytogenes J2818] gi\|254937086 - gi\|254937086\|ref\|ZP_05268783.1\| tryptophanyl-tRNA synthetase [Listeria monocytogenes F6900] gi\|224498944 - gi\|224498944\|ref\|ZP_03667293.1\| tryptophanyl-tRNA synthetase [Listeria monocytogenes Finland 1988] gi\|217332910, gi... - gi\|217963640\|ref\|YP_002349318.1\| tryptophanyl-tRNA synthetase [Listeria monocytogenes HCC23], gi\|217... SYW_LISMO - Tryptophan--tRNA ligase OS=Listeria monocytogenes serovar 1/2a (strain ATCC BAA-679 / EGD-e) GN=trpS... gi\|224501002 - gi\|224501002\|ref\|ZP_03669309.1\| tryptophanyl-tRNA synthetase [Listeria monocytogenes FSL R2-561] gi\|47095772, gi\|... - gi\|47095772\|ref\|ZP_00233378.1\| tryptophanyl-tRNA synthetase [Listeria monocytogenes str. 1/2a F6854]...	0.0	[2..329]	[3..330]

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Predicted Domain #1

Region A:
Residues: [1-329]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MSVIFSGIQP SGTITLGNYL GAMKQFTELQ NEHDCYFCIV NQHAITVPQD PVQLRKNIRS  60
   61 LAALYVACGI DPEKATLFVQ SEVPAHAQLG WIMQSVAYVG ELERMTQYKD KASGRDSVPA 120
  121 GLLTYPPLMA ADILLYNTEI VPVGDDQKQH MELTRDLAER FNKRFREVFT IPEIRIPKVG 180
  181 ARVMSLTEPT KKMSKSDPNP KSMISMLDEP KTIEKKIKSA VTDSEGIVKF DKENKPGISN 240
  241 LLTIYSSFSG KTVEEIEAMY EGKGYGDFKG DLAQVVVEAI RPIQDKYNEL INSPELDEIL 300
  301 DKGAEKANRV AFKQLRKVEN AMGLSRKRR

[Run NCBI BLAST on this sequence.]

Detection Method:	PSI-BLAST
Confidence:	109.0
Match:	1i6kA
Description:	Tryptophanyl-tRNA synthetase (TrpRS)
Matching Structure (courtesy of the PDB):

Predicted functions:

Term	Confidence	Notes
ligase activity, forming carbon-oxygen bonds	7.16276509815667	bayes_pls_golite062009
ligase activity, forming aminoacyl-tRNA and related compounds	7.16276509815667	bayes_pls_golite062009
aminoacyl-tRNA ligase activity	7.13957775963187	bayes_pls_golite062009
ligase activity	6.11211476973434	bayes_pls_golite062009
tryptophan-tRNA ligase activity	5.34430928486195	bayes_pls_golite062009
glutamate-tRNA ligase activity	2.63681738794687	bayes_pls_golite062009
methionine-tRNA ligase activity	2.56893064485672	bayes_pls_golite062009
catalytic activity	2.37674226834122	bayes_pls_golite062009
tyrosine-tRNA ligase activity	1.88984817882585	bayes_pls_golite062009
arginine-tRNA ligase activity	1.50161401062914	bayes_pls_golite062009
cysteine-tRNA ligase activity	0.844943947059557	bayes_pls_golite062009
binding	0.535704308663141	bayes_pls_golite062009
nucleic acid binding	0.449504767632354	bayes_pls_golite062009
nucleotidyltransferase activity	0.2293846471193	bayes_pls_golite062009
transferase activity, transferring phosphorus-containing groups	0.126511747475258	bayes_pls_golite062009
glutamine-tRNA ligase activity	0.118292082006187	bayes_pls_golite062009

TMHMM	2.0c	PSIPRED	v2.61
SignalP	3.0	COILS	1999
DISOPRED	v0.1	NCBI nr	06/2007
PSI-BLAST	2.2.18	FFAS	ffas03
PDB	06/2007	Pfam	22
HMMER	2.3.2

View Structure Prediction Details

Top Sequence Alignment Hits

Predicted functions: