YRC Public Data Repository - Protein Structure Prediction

Protein:	gi\|30260419, gi\|...
Organism:	Bacillus anthracis str. Ames
Length:	390 amino acids
Reference:	Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16

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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for gi|30260419, gi|....

Description	E-value	Query Range	Subject Range
gi\|52144997, gi\|... - gi\|52144997\|ref\|YP_081832.1\| homogentisate 1,2-dioxygenase [Bacillus cereus E33L], gi\|51978466\|gb\|AA...	0.0	[1..390]	[1..390]
gi\|49479914, gi\|... - gi\|49479914\|ref\|YP_034570.1\| homogentisate 1,2-dioxygenase [Bacillus thuringiensis serovar konkukian...	0.0	[1..390]	[1..390]
gi\|42779343, gi\|... - gi\|42779343\|ref\|NP_976590.1\| homogentisate 1,2-dioxygenase, putative [Bacillus cereus ATCC 10987], g...	0.0	[1..390]	[1..390]
gi\|47555881, gi\|... - gi\|47567479\|ref\|ZP_00238191.1\| homogentisate 1,2-dioxygenase [Bacillus cereus G9241], gi\|47555881\|gb...	0.0	[1..390]	[1..390]
gi\|89205759, gi\|... - gi\|89205759\|ref\|ZP_01184326.1\| Homogentisate 1,2-dioxygenase [Bacillus weihenstephanensis KBAB4], gi...	0.0	[1..390]	[1..390]
HGD_MOUSE - Homogentisate 1,2-dioxygenase OS=Mus musculus GN=Hgd PE=1 SV=2	0.0	[3..382]	[19..428]
gi\|109033293 - gi\|109033293\|ref\|XP_001110996.1\| PREDICTED: homogentisate 1,2-dioxygenase isoform 2 [Macaca mulatta]	0.0	[3..382]	[19..428]
gi\|74002858 - gi\|74002858\|ref\|XP_535754.2\| PREDICTED: similar to Homogentisate 1,2-dioxygenase (Homogentisicase) (...	0.0	[3..382]	[16..425]

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Predicted Domain #1

Region A:
Residues: [1-390]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MFYRHMGELP HKRHVQFRKK DGSLYREQVM GTKGFSGTQS ILYHHYMPTE VGHAALSHSC  60
   61 QLQYEEDVVL SHRHFRTKEN KKSGDAVSGR NFILGNEDLL IGVVTPTEKM NYFYRNGDGD 120
  121 EMLFVHYGTG KIETMFGTIH YRKGDYVTIP IGTIYRVIPD EGETKFLVVE ANSQITTPRR 180
  181 YRNEYGQLLE HSPFCERDIR GPEKLETYDE KGEFVVMTKS RGYMHKHVLG HHPLDVVGWD 240
  241 GYLYPWVFNV EDFEPITGRI HQPPPVHQTF EGHNFVICSF VPRLYDYHPE SIPAPYYHSN 300
  301 VNSDEVLYYV EGNFMSRKGV EEGSITLHPS GIPHGPHPGK TEASIGKKET LELAVMIDTF 360
  361 RPLRIVKQAH ETEDEKYMYS WIEEGSYTVK

[Run NCBI BLAST on this sequence.]

Detection Method:	PSI-BLAST
Confidence:	153.0
Match:	1ey2A
Description:	Homogentisate dioxygenase
Matching Structure (courtesy of the PDB):

Predicted functions:

Term	Confidence	Notes
oxidoreductase activity, acting on single donors with incorporation of molecular oxygen	2.65960759413149	bayes_pls_golite062009
oxidoreductase activity, acting on single donors with incorporation of molecular oxygen, incorporation of two atoms of oxygen	2.611114803333	bayes_pls_golite062009
homogentisate 1,2-dioxygenase activity	2.36574960723119	bayes_pls_golite062009
dioxygenase activity	0.930778069601015	bayes_pls_golite062009
catalytic activity	0.401988496917198	bayes_pls_golite062009

TMHMM	2.0c	PSIPRED	v2.61
SignalP	3.0	COILS	1999
DISOPRED	v0.1	NCBI nr	06/2007
PSI-BLAST	2.2.18	FFAS	ffas03
PDB	06/2007	Pfam	22
HMMER	2.3.2

View Structure Prediction Details

Top Sequence Alignment Hits

Predicted functions: