YRC Public Data Repository - Protein Structure Prediction

Protein:	gi\|39997388, gi\|...
Organism:	Geobacter sulfurreducens PCA
Length:	201 amino acids
Reference:	Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16

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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for gi|39997388, gi|....

Description	E-value	Query Range	Subject Range
gi\|15606301, gi\|... - gi\|2983496\|gb\|AAC07074.1\| pyrazinamidase/nicotinamidase [Aquifex aeolicus VF5], gi\|15606301\|ref\|NP_2... gi\|7445162 - pir\|\|B70386 pyrazinamidase/nicotinamidase - Aquifex aeolicus	200.0	[0..1]	[196..5]
gi\|5458403, gi\|7... - pir\|\|F75073 pyrazinamidase/nicotinamidase PAB1720 - Pyrococcus abyssi (strain Orsay), gi\|5458403\|em... gi\|5458403, gi\|1... - gi\|5458403\|emb\|CAB49891.1\| Amidase related to nicotinamidase [Pyrococcus abyssi GE5], gi\|14521185\|re...	197.0	[0..1]	[189..1]
gi\|57159909, gi\|... - gi\|57641585\|ref\|YP_184063.1\| nicotinamidase [Thermococcus kodakarensis KOD1], gi\|57159909\|dbj\|BAD858...	195.0	[0..1]	[187..1]
gi\|238794512, gi... - gi\|77977679\|ref\|ZP_00833121.1\| COG1335: Amidases related to nicotinamidase [Yersinia intermedia ATCC...	193.0	[0..3]	[197..1]
gi\|14590841, gi\|... - gi\|3257413\|dbj\|BAA30096.1\| 180aa long hypothetical pyrazinamidase/nicotinamidase [Pyrococcus horikos... gi\|17943390, gi\|... - pir\|\|B71092 probable pyrazinamidase/nicotinamidase - Pyrococcus horikoshii, gi\|17943390\|pdb\|1ILW\|A ...	192.0	[0..1]	[188..1]
gi\|238797351, gi... - gi\|77962069\|ref\|ZP_00825895.1\| COG1335: Amidases related to nicotinamidase [Yersinia mollaretii ATCC...	190.0	[0..3]	[197..1]
gi\|18977477, gi\|... - gi\|18977477\|ref\|NP_578834.1\| pyrazinamidase/nicotinamidase pxnc [Pyrococcus furiosus DSM 3638], gi\|1...	189.0	[0..1]	[187..1]
gi\|238786165, gi... - gi\|77956446\|ref\|ZP_00820544.1\| COG1335: Amidases related to nicotinamidase [Yersinia bercovieri ATCC...	188.0	[0..3]	[197..1]
gi\|49611795, gi\|... - gi\|50121269\|ref\|YP_050436.1\| nicotinamidase/pyrazinamidase [Pectobacterium atrosepticum SCRI1043], g...	187.0	[0..3]	[197..1]
gi\|77629169, gi\|... - gi\|77629169\|ref\|ZP_00791755.1\| COG1335: Amidases related to nicotinamidase [Yersinia pseudotuberculo...	187.0	[0..3]	[196..1]

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Predicted Domain #1

Region A:
Residues: [1-201]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MENDAALLIV DVQNDFCPGG SLAVPEGDTV VPVLNGYISV FRTAGLPIFA SRDWHPRMTS  60
   61 HFKEHGGQWP VHCVQGSHGA QFHPDLALPG NAIVISKGMD PERDDYSAFQ GTAADGTPLP 120
  121 TLLAARGIRH LYLGGLATDY CVKESALEGI RHGLIVTVLT DASRGVDLAP GDSERAVQEM 180
  181 MRAGVRMTSL EGIRQEQRLR E

[Run NCBI BLAST on this sequence.]

Detection Method:	PSI-BLAST
Confidence:	49.221849
Match:	1ilwA
Description:	Pyrazinamidase/nicotinamidase
Matching Structure (courtesy of the PDB):

Predicted functions:

Term	Confidence	Notes
nicotinamidase activity	2.590271821288	bayes_pls_golite062009
binding	1.80707112356899	bayes_pls_golite062009
hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in linear amides	1.33901087189475	bayes_pls_golite062009
catalytic activity	0.992051062697807	bayes_pls_golite062009
protein binding	0.343971697425971	bayes_pls_golite062009

TMHMM	2.0c	PSIPRED	v2.61
SignalP	3.0	COILS	1999
DISOPRED	v0.1	NCBI nr	06/2007
PSI-BLAST	2.2.18	FFAS	ffas03
PDB	06/2007	Pfam	22
HMMER	2.3.2

View Structure Prediction Details

Top Sequence Alignment Hits

Predicted functions: