YRC Public Data Repository - Protein Structure Prediction

Protein:	gi\|30039868, gi\|...
Organism:	Shigella flexneri 2a str. 2457T
Length:	231 amino acids
Reference:	Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16

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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for gi|30039868, gi|....

Description	E-value	Query Range	Subject Range
gi\|68195862, gi\|... - gi\|69245332\|ref\|ZP_00603376.1\| Class II aldolase/adducin, N-terminal [Enterococcus faecium DO], gi\|6... gi\|48825725 - ref\|ZP_00286965.1\| COG0235: Ribulose-5-phosphate 4-epimerase and related epimerases and aldolases [E...	278.0	[0..1]	[231..1]
gi\|82542665, gi\|... - gi\|82542665\|ref\|YP_406612.1\| L-ribulose-5-phosphate 4-epimerase [Shigella boydii Sb227], gi\|81244076... gi\|187730282, gi... - gi\|75175619\|ref\|ZP_00695827.1\| COG0235: Ribulose-5-phosphate 4-epimerase and related epimerases and ...	275.0	[0..1]	[231..1]
gi\|209917252, gi... - gi\|209917252\|ref\|YP_002291336.1\| L-ribulose-5-phosphate 4-epimerase [Escherichia coli SE11], gi\|2099... gi\|218552644, gi... - gi\|218552644\|ref\|YP_002385557.1\| L-ribulose-5-phosphate 4-epimerase [Escherichia coli IAI1], gi\|2183... gi\|75189163, gi\|... - gi\|75189163\|ref\|ZP_00702430.1\| COG0235: Ribulose-5-phosphate 4-epimerase and related epimerases and ...	275.0	[0..1]	[231..1]
gi\|218350263, gi... - gi\|218693531\|ref\|YP_002401198.1\| L-ribulose-5-phosphate 4-epimerase [Escherichia coli 55989], gi\|218... ARAD_ECOLI - L-ribulose-5-phosphate 4-epimerase (EC 5.1.3.4) (Phosphoribulose isomerase) - Escherichia coli gi\|89106945, gi\|... - gi\|89106945\|ref\|AP_000725.1\| L-ribulose-5-phosphate 4-epimerase [Escherichia coli str. K-12 substr. ... gi\|124530630, gi... - gi\|124530630\|ref\|ZP_01701214.1\| L-ribulose-5-phosphate 4-epimerase [Escherichia coli B], gi\|12449905... gi\|254037477, gi... - gi\|254037477\|ref\|ZP_04871554.1\| L-ribulose-5-phosphate 4-epimerase [Escherichia sp. 1_1_43], gi\|2268... EG10055 - L-ribulose-5-phosphate 4-epimerase / L-ribulose-5-phosphate 4-epimerase gi\|75234300, gi\|... - gi\|75234300\|ref\|ZP_00718678.1\| COG0235: Ribulose-5-phosphate 4-epimerase and related epimerases and ... EG10055 - L-ribulose-5-phosphate 4-epimerase / L-ribulose-5-phosphate 4-epimerase gi\|157065210, gi... - gi\|75194280\|ref\|ZP_00704350.1\| COG0235: Ribulose-5-phosphate 4-epimerase and related epimerases and ... gi\|169756511, gi... - gi\|170021583\|ref\|YP_001726537.1\| L-ribulose-5-phosphate 4-epimerase [Escherichia coli ATCC 8739], gi... gi\|191167766, gi... - gi\|75229088\|ref\|ZP_00715668.1\| COG0235: Ribulose-5-phosphate 4-epimerase and related epimerases and ...	274.0	[0..1]	[231..1]
gi\|74310678, gi\|... - gi\|74310678\|ref\|YP_309097.1\| L-ribulose-5-phosphate 4-epimerase [Shigella sonnei Ss046], gi\|73854155...	274.0	[0..1]	[231..1]
gi\|12721601, gi\|... - gi\|15603109\|ref\|NP_246181.1\| L-ribulose-5-phosphate 4-epimerase [Pasteurella multocida subsp. multoc...	274.0	[0..1]	[231..13]
gi\|75511715, gi\|... - gi\|75511715\|ref\|ZP_00734353.1\| COG0235: Ribulose-5-phosphate 4-epimerase and related epimerases and ...	274.0	[0..1]	[231..1]
ARAD_SALTY - L-ribulose-5-phosphate 4-epimerase OS=Salmonella typhimurium GN=araD PE=3 SV=3 gi\|238911158 - gi\|238911158\|ref\|ZP_04654995.1\| L-ribulose-5-phosphate 4-epimerase [Salmonella enterica subsp. enter... lcl\|NC_016856.1_... - [gene=araD] [protein=L-ribulose-5-phosphate 4-epimerase] [protein_id=YP_005235753.1] [location=compl... gi\|194449950, gi... - gi\|194449950\|ref\|YP_002044069.1\| L-ribulose-5-phosphate 4-epimerase [Salmonella enterica subsp. ente... gi\|197242475, gi... - gi\|197264220\|ref\|ZP_03164294.1\| L-ribulose-5-phosphate 4-epimerase [Salmonella enterica subsp. enter... ARAD_SALTY - L-ribulose-5-phosphate 4-epimerase OS=Salmonella typhimurium GN=araD PE=3 SV=3 ARAD_SALTY - L-ribulose-5-phosphate 4-epimerase OS=Salmonella typhimurium (strain LT2 / SGSC1412 / ATCC 700720) G... gi\|167989967, gi... - gi\|205331551\|gb\|EDZ18315.1\| L-ribulose-5-phosphate 4-epimerase [Salmonella enterica subsp. enterica ... gi\|168243490, gi... - gi\|205337473\|gb\|EDZ24237.1\| L-ribulose-5-phosphate 4-epimerase [Salmonella enterica subsp. enterica ... gi\|168820912, gi... - gi\|205342396\|gb\|EDZ29160.1\| L-ribulose-5-phosphate 4-epimerase [Salmonella enterica subsp. enterica ...	272.0	[0..1]	[231..1]
gi\|199604716, gi... - gi\|200387618\|ref\|ZP_03214230.1\| L-ribulose-5-phosphate 4-epimerase [Salmonella enterica subsp. enter... gi\|62126298, gi\|... - gi\|62178665\|ref\|YP_215082.1\| L-ribulose-5-phosphate 4-epimerase [Salmonella enterica subsp. enterica...	272.0	[0..1]	[231..1]
gi\|168771283, gi... - gi\|189359915\|gb\|EDU78334.1\| L-ribulose-5-phosphate 4-epimerase [Escherichia coli O157:H7 str. EC4486... gi\|168764062, gi... - gi\|189365876\|gb\|EDU84292.1\| L-ribulose-5-phosphate 4-epimerase [Escherichia coli O157:H7 str. EC4501... gi\|189357097, gi... - gi\|189357097\|gb\|EDU75516.1\| L-ribulose-5-phosphate 4-epimerase [Escherichia coli O157:H7 str. EC4401... gi\|188014527, gi... - gi\|188014527\|gb\|EDU52649.1\| L-ribulose-5-phosphate 4-epimerase [Escherichia coli O157:H7 str. EC4113... gi\|81239615, gi\|... - gi\|82775467\|ref\|YP_401814.1\| L-ribulose-5-phosphate 4-epimerase [Shigella dysenteriae Sd197], gi\|812... gi\|209746824, gi... - pir\|\|A85488 L-ribulose-5-phosphate 4-epimerase - Escherichia coli (strain O157:H7, substrain EDL933... gi\|217326432, gi... - gi\|217326432\|ref\|ZP_03442516.1\| L-ribulose-5-phosphate 4-epimerase [Escherichia coli O157:H7 str. TW... gi\|209157864, gi... - gi\|209396464\|ref\|YP_002268669.1\| L-ribulose-5-phosphate 4-epimerase [Escherichia coli O157:H7 str. E... gi\|15799745, gi\|... - gi\|15799745\|ref\|NP_285757.1\| L-ribulose-5-phosphate 4-epimerase [Escherichia coli O157:H7 EDL933], g... gi\|254590599, gi... - gi\|254791199\|ref\|YP_003076036.1\| L-ribulose-5-phosphate 4-epimerase [Escherichia coli O157:H7 str. T... gi\|13359521, gi\|... - gi\|15829319\|ref\|NP_308092.1\| L-ribulose-5-phosphate 4-epimerase [Escherichia coli O157:H7], gi\|13359... gi\|189376356, gi... - gi\|189376356\|gb\|EDU94772.1\| L-ribulose-5-phosphate 4-epimerase [Escherichia coli O157:H7 str. EC508]... gi\|168789586, gi... - gi\|189370832\|gb\|EDU89248.1\| L-ribulose-5-phosphate 4-epimerase [Escherichia coli O157:H7 str. EC869]... gi\|168781944, gi... - gi\|189000393\|gb\|EDU69379.1\| L-ribulose-5-phosphate 4-epimerase [Escherichia coli O157:H7 str. EC4076... gi\|168776903, gi... - gi\|187767752\|gb\|EDU31596.1\| L-ribulose-5-phosphate 4-epimerase [Escherichia coli O157:H7 str. EC4196... gi\|13359521, gi\|... - gi\|15829319\|ref\|NP_308092.1\| L-ribulose-5-phosphate 4-epimerase [Escherichia coli O157:H7 str. Sakai... gi\|208742052, gi... - gi\|208821929\|ref\|ZP_03262249.1\| L-ribulose-5-phosphate 4-epimerase [Escherichia coli O157:H7 str. EC... gi\|208734268, gi... - gi\|208812991\|ref\|ZP_03254320.1\| L-ribulose-5-phosphate 4-epimerase [Escherichia coli O157:H7 str. EC... gi\|208727914, gi... - gi\|208808113\|ref\|ZP_03250450.1\| L-ribulose-5-phosphate 4-epimerase [Escherichia coli O157:H7 str. EC... gi\|195939277 - gi\|195939277\|ref\|ZP_03084659.1\| L-ribulose-5-phosphate 4-epimerase [Escherichia coli O157:H7 str. EC...	272.0	[0..1]	[231..1]

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Predicted Domain #1

Region A:
Residues: [1-231]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MLKDLKRQVL EANLALPKHN LVTLTWGNVS AVDRERGVFV IKPSGVDYSV MTADDMVVVS  60
   61 IETGEVVEGT KKPSSDTPTH RLLYQAFPSI GGIVHTHSRH ATIWAQAGQS IPATGTTHAD 120
  121 YFYGTIPCTR KMTDAEINGE YEWETGNVIV ETFEKQGIDA AQMPGVLVHS HGPFAWGKNA 180
  181 EDAVHNAIVL EEVAYMGIFC RQLAPQLPDM QQTLLDKHYL RKHGAKAYYG Q

[Run NCBI BLAST on this sequence.]

Detection Method:	PSI-BLAST
Confidence:	72.69897
Match:	1jdiA
Description:	L-ribulose-5-phosphate 4-epimerase
Matching Structure (courtesy of the PDB):

Predicted functions:

Term	Confidence	Notes
L-ribulose-phosphate 4-epimerase activity	3.50507333471987	bayes_pls_golite062009
L-fuculose-phosphate aldolase activity	2.43949811564444	bayes_pls_golite062009
catalytic activity	1.9511172460719	bayes_pls_golite062009
aldehyde-lyase activity	1.08084403816388	bayes_pls_golite062009
lyase activity	0.77829514510632	bayes_pls_golite062009
racemase and epimerase activity, acting on carbohydrates and derivatives	0.42493443904865	bayes_pls_golite062009
carbon-carbon lyase activity	0.2178091782272	bayes_pls_golite062009
racemase and epimerase activity	0.15063402811264	bayes_pls_golite062009
isomerase activity	0.0458367676418101	bayes_pls_golite062009

TMHMM	2.0c	PSIPRED	v2.61
SignalP	3.0	COILS	1999
DISOPRED	v0.1	NCBI nr	06/2007
PSI-BLAST	2.2.18	FFAS	ffas03
PDB	06/2007	Pfam	22
HMMER	2.3.2

View Structure Prediction Details

Top Sequence Alignment Hits

Predicted functions: