YRC Public Data Repository - Protein Structure Prediction

Protein:	Y1260_COXBU
Organism:	Coxiella burnetii RSA 493
Length:	248 amino acids
Reference:	Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16

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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for Y1260_COXBU.

Description	E-value	Query Range	Subject Range
gi\|26107378, gi\|... - gi\|26246978\|ref\|NP_753018.1\| outer membrane protein A [Escherichia coli CFT073], gi\|26107378\|gb\|AAN7...	196.0	[0..2]	[248..30]
gi\|56413933, gi\|... - gi\|56413933\|ref\|YP_151008.1\| outer membrane protein A [Salmonella enterica subsp. enterica serovar P... gi\|197362856, gi... - gi\|197362856\|ref\|YP_002142493.1\| outer membrane protein A [Salmonella enterica subsp. enterica serov...	195.0	[0..2]	[248..1]
gi\|62127225, gi\|... - gi\|62179592\|ref\|YP_216009.1\| outer membrane protein A [Salmonella enterica subsp. enterica serovar C...	195.0	[0..2]	[248..1]
OMPA_SALTY - Outer membrane protein A OS=Salmonella typhimurium GN=ompA PE=3 SV=2 OMPA_SALTY - Outer membrane protein A OS=Salmonella typhimurium GN=ompA PE=3 SV=2 OMPA_SALTY - Outer membrane protein A OS=Salmonella typhimurium (strain LT2 / SGSC1412 / ATCC 700720) GN=ompA PE=... gi\|205352225, gi... - gi\|205352225\|ref\|YP_002226026.1\| outer membrane protein A [Salmonella enterica subsp. enterica serov... gi\|206708218, gi... - gi\|207856415\|ref\|YP_002243066.1\| outer membrane protein A [Salmonella enterica subsp. enterica serov... lcl\|NC_016856.1_... - [gene=ompA] [protein=outer membrane protein A] [protein_id=YP_005236803.1] [location=complement(1119...	194.0	[0..2]	[248..1]
gi\|237707059, gi... - gi\|237707059\|ref\|ZP_04537540.1\| outer membrane protein A [Escherichia sp. 3_2_53FAA], gi\|226898269\|g... gi\|91210052, gi\|... - gi\|91210052\|ref\|YP_540038.1\| outer membrane protein A [Escherichia coli UTI89], gi\|91071626\|gb\|ABE06...	194.0	[0..2]	[248..30]
gi\|84779528, gi\|... - gi\|85059008\|ref\|YP_454710.1\| outer membrane protein A [Sodalis glossinidius str. 'morsitans'], gi\|84...	194.0	[0..14]	[248..5]
gi\|117623167, gi... - gi\|117623167\|ref\|YP_852080.1\| outer membrane protein A [Escherichia coli APEC O1], gi\|115512291\|gb\|A...	193.0	[0..2]	[248..25]
gi\|29137907, gi\|... - gi\|29142277\|ref\|NP_805619.1\| outer membrane protein A [Salmonella enterica subsp. enterica serovar T... gi\|16759951 - gi\|16759951\|ref\|NP_455568.1\| outer membrane protein A [Salmonella enterica subsp. enterica serovar T... OMPA_SALTI - Outer membrane protein A OS=Salmonella typhi GN=ompA PE=3 SV=1 OMPA_SALTI - Outer membrane protein A OS=Salmonella typhi GN=ompA PE=3 SV=1	193.0	[0..2]	[248..1]
gi\|72587, gi\|758341 - gi\|758341\|emb\|CAA26037.1\| outer membrane protein (ompA) [Salmonella typhimurium], pir\|\|MMEBAT outer ... gi\|758341\|emb\|CA... - outer membrane protein (ompA) [Salmonella typhimurium]	193.0	[0..2]	[248..1]
gi\|81240395, gi\|... - gi\|82776247\|ref\|YP_402596.1\| outer membrane protein A [Shigella dysenteriae Sd197], gi\|81240395\|gb\|A...	192.0	[0..2]	[248..1]

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Predicted Domain #1

Region A:
Residues: [1-248]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MLKKIVIGVT ATAAFGIGAG ALAGGSVDQS YNNTSGAGFY VRGEAGYGLV DKKSGTSKVN  60
   61 FTGVTLTENS HTNTKKSRGF NGRVAIGYAF NPYFSLESGF TYYHPAYRDV NIAGSALPLF 120
  121 SSVQAEGRQK INLYSIDLMG KATLPIDNFY AFIEGGVAYV HTKFVAFTET GTAVSPLLPP 180
  181 VTSSVAVKVP SSSKGYIRPK AGIGVGYNIT QNIGVDVSYS RVFGQGKINN TNYLPNLNAV 240
  241 TLGLTYKF

[Run NCBI BLAST on this sequence.]

Detection Method:	PSI-BLAST
Confidence:	37.522879
Match:	1bxwA
Description:	Outer membrane protein A (OMPA) transmembrane domain
Matching Structure (courtesy of the PDB):

Predicted functions:

Term	Confidence	Notes
porin activity	3.72603691775929	bayes_pls_golite062009
wide pore channel activity	2.56764837317779	bayes_pls_golite062009
channel activity	0.500502774665998	bayes_pls_golite062009
passive transmembrane transporter activity	0.500502774665998	bayes_pls_golite062009
transporter activity	0.32956132877646	bayes_pls_golite062009
transmembrane transporter activity	0.31625101261287	bayes_pls_golite062009

TMHMM	2.0c	PSIPRED	v2.61
SignalP	3.0	COILS	1999
DISOPRED	v0.1	NCBI nr	06/2007
PSI-BLAST	2.2.18	FFAS	ffas03
PDB	06/2007	Pfam	22
HMMER	2.3.2

View Structure Prediction Details

Top Sequence Alignment Hits

Predicted functions: