YRC Public Data Repository - Protein Structure Prediction

Protein:	ORN_COXBU
Organism:	Coxiella burnetii RSA 493
Length:	183 amino acids
Reference:	Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16

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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for ORN_COXBU.

Description	E-value	Query Range	Subject Range
gi\|83727484, gi\|... - gi\|83745794\|ref\|ZP_00942851.1\| Oligoribonuclease [Ralstonia solanacearum UW551], gi\|83727484\|gb\|EAP7...	187.0	[0..2]	[180..94]
gi\|90022321, gi\|... - gi\|90022321\|ref\|YP_528148.1\| oligoribonuclease [Saccharophagus degradans 2-40], gi\|89951921\|gb\|ABD81...	184.0	[0..1]	[181..1]
ORN_RALSO - Oligoribonuclease OS=Ralstonia solanacearum (strain GMI1000) GN=orn PE=3 SV=1 ORN_RALSO - Oligoribonuclease OS=Ralstonia solanacearum GN=orn PE=3 SV=1	183.0	[0..2]	[180..24]
ORN_BORA1 - Oligoribonuclease OS=Bordetella avium (strain 197N) GN=orn PE=3 SV=1	182.0	[0..1]	[181..1]
gi\|116183146, gi... - gi\|75853534\|ref\|ZP_00761360.1\| COG1949: Oligoribonuclease (3'->5' exoribonuclease) [Vibrio sp. Ex25]...	181.0	[0..1]	[181..1]
gi\|93355362, gi\|... - gi\|94311510\|ref\|YP_584720.1\| oligoribonuclease [Ralstonia metallidurans CH34], gi\|93355362\|gb\|ABF094...	181.0	[0..3]	[182..10]
ORN_BORBR - Oligoribonuclease OS=Bordetella bronchiseptica GN=orn PE=3 SV=1 ORN_BORPA - Oligoribonuclease OS=Bordetella parapertussis (strain 12822 / ATCC BAA-587 / NCTC 13253) GN=orn PE=3... ORN_BORPA - Oligoribonuclease OS=Bordetella parapertussis GN=orn PE=3 SV=1 ORN_BORBR - Oligoribonuclease OS=Bordetella bronchiseptica (strain ATCC BAA-588 / NCTC 13252 / RB50) GN=orn PE=3... ORN_BORPE - Oligoribonuclease OS=Bordetella pertussis GN=orn PE=3 SV=1 ORN_BORPE - Oligoribonuclease OS=Bordetella pertussis (strain Tohama I / ATCC BAA-589 / NCTC 13251) GN=orn PE=3 ...	180.0	[0..1]	[180..1]
gi\|27364686, gi\|... - gi\|27364686\|ref\|NP_760214.1\| oligoribonuclease [Vibrio vulnificus CMCP6], gi\|27360831\|gb\|AAO09741.1\|...	180.0	[0..1]	[181..32]
ORN_VIBPA - Oligoribonuclease OS=Vibrio parahaemolyticus GN=orn PE=3 SV=1 ORN_VIBPA - Oligoribonuclease OS=Vibrio parahaemolyticus serotype O3:K6 (strain RIMD 2210633) GN=orn PE=3 SV=1 gi\|149745937, gi... - gi\|153840401\|ref\|ZP_01993068.1\| oligoribonuclease [Vibrio parahaemolyticus AQ3810], gi\|149745937\|gb\|...	180.0	[0..1]	[181..1]
gi\|37681261, gi\|... - gi\|37681261\|ref\|NP_935870.1\| oligoribonuclease [Vibrio vulnificus YJ016], gi\|37200012\|dbj\|BAC95841.1...	180.0	[0..1]	[181..47]

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Predicted Domain #1

Region A:
Residues: [1-183]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MDFSDDNLIW LDLEMTGLDP ERDRIIEIAT IVTNSHLDIL AEGPAFAIHQ PDKLLTAMDN  60
   61 WNTSHHTASG LLERVKNSSV DEVEAETLTL AFLEKYVSAG KSPLCGNSVC QDRRFLSRYM 120
  121 PRLNQFFHYR HLDVTTLKIL AQRWAPQIAA AHIKESQHLA LQDIRDSIEE LRYYRAHLLN 180
  181 LSK

[Run NCBI BLAST on this sequence.]

Detection Method:	PSI-BLAST
Confidence:	44.0
Match:	1ytaA
Description:	Crystal Structure of Oligoribonuclease, the lone essential exoribonuclease in Escherichia coli
Matching Structure (courtesy of the PDB):

Predicted functions:

Term	Confidence	Notes
ribonuclease activity	4.81599779544001	bayes_pls_golite062009
exoribonuclease activity	3.01417328311605	bayes_pls_golite062009
ribonuclease H activity	2.91966688044755	bayes_pls_golite062009
exoribonuclease activity, producing 5'-phosphomonoesters	2.89077854960958	bayes_pls_golite062009
hydrolase activity, acting on ester bonds	2.70794511869438	bayes_pls_golite062009
nuclease activity	2.65398446409354	bayes_pls_golite062009
endonuclease activity	2.63074055051349	bayes_pls_golite062009
endoribonuclease activity	2.59247838057313	bayes_pls_golite062009
hydrolase activity	2.41899414621161	bayes_pls_golite062009
transcription regulator activity	2.20855917457806	bayes_pls_golite062009
binding	1.8781442498221	bayes_pls_golite062009
endoribonuclease activity, producing 5'-phosphomonoesters	1.74431545836806	bayes_pls_golite062009
nucleic acid binding	1.72558334058697	bayes_pls_golite062009
DNA binding	1.62101283948059	bayes_pls_golite062009
endonuclease activity, active with either ribo- or deoxyribonucleic acids and producing 5'-phosphomonoesters	1.59628511603826	bayes_pls_golite062009
exonuclease activity	1.4327316829508	bayes_pls_golite062009
3'-5'-exoribonuclease activity	1.42069917818896	bayes_pls_golite062009
catalytic activity	1.25233849524628	bayes_pls_golite062009
	1.18236432793831	bayes_pls_golite062009
transcription factor activity	0.971926865662649	bayes_pls_golite062009
3'-5' exonuclease activity	0.86862629020506	bayes_pls_golite062009
RNA binding	0.750194803368593	bayes_pls_golite062009
exonuclease activity, active with either ribo- or deoxyribonucleic acids and producing 5'-phosphomonoesters	0.389326716045122	bayes_pls_golite062009
transcription activator activity	0.104967281174106	bayes_pls_golite062009

TMHMM	2.0c	PSIPRED	v2.61
SignalP	3.0	COILS	1999
DISOPRED	v0.1	NCBI nr	06/2007
PSI-BLAST	2.2.18	FFAS	ffas03
PDB	06/2007	Pfam	22
HMMER	2.3.2

View Structure Prediction Details

Top Sequence Alignment Hits

Predicted functions: