YRC Public Data Repository - Protein Structure Prediction

Protein:	RNPH_COXBU
Organism:	Coxiella burnetii RSA 493
Length:	237 amino acids
Reference:	Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16

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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for RNPH_COXBU.

Description	E-value	Query Range	Subject Range
gi\|107104436 - gi\|107104436\|ref\|ZP_01368354.1\| hypothetical protein PaerPA_01005513 [Pseudomonas aeruginosa PACS2]	284.0	[0..2]	[237..3]
RNPH_PSEA7 - Ribonuclease PH OS=Pseudomonas aeruginosa (strain PA7) GN=rph PE=3 SV=1	283.0	[0..2]	[237..3]
RNPH_PSEA8 - Ribonuclease PH OS=Pseudomonas aeruginosa (strain LESB58) GN=rph PE=3 SV=1 gi\|254237972, gi... - gi\|84317970\|ref\|ZP_00966404.1\| COG0689: RNase PH [Pseudomonas aeruginosa C3719], gi\|254237972\|ref\|ZP... gi\|254243780, gi... - gi\|84323960\|ref\|ZP_00972025.1\| COG0689: RNase PH [Pseudomonas aeruginosa 2192], gi\|254243780\|ref\|ZP_... RNPH_PSEAB - Ribonuclease PH OS=Pseudomonas aeruginosa (strain UCBPP-PA14) GN=rph PE=3 SV=1 RNPH_PSEAE - Ribonuclease PH OS=Pseudomonas aeruginosa GN=rph PE=1 SV=2 RNPH_PSEAE - Ribonuclease PH OS=Pseudomonas aeruginosa (strain ATCC 15692 / PAO1 / 1C / PRS 101 / LMG 12228) GN=r...	282.0	[0..2]	[237..3]
RNPH_VIBF1 - Ribonuclease PH OS=Vibrio fischeri (strain ATCC 700601 / ES114) GN=rph PE=3 SV=1	280.0	[0..1]	[237..1]
gi\|49082078 - gi\|49082078\|gb\|AAT50439.1\| PA5334 [synthetic construct]	279.0	[0..2]	[237..3]
gi\|67154919 - gi\|67154919\|ref\|ZP_00416664.1\| Ribonuclease PH [Azotobacter vinelandii AvOP] RNPH_AZOVD - Ribonuclease PH OS=Azotobacter vinelandii (strain DJ / ATCC BAA-1303) GN=rph PE=3 SV=1	278.0	[0..2]	[237..3]
RNPH_COLP3 - Ribonuclease PH OS=Colwellia psychrerythraea (strain 34H / ATCC BAA-681) GN=rph PE=3 SV=1	277.0	[0..1]	[237..1]
RNPH_VIBVU - Ribonuclease PH OS=Vibrio vulnificus (strain CMCP6) GN=rph PE=3 SV=1 RNPH_VIBVY - Ribonuclease PH OS=Vibrio vulnificus (strain YJ016) GN=rph PE=3 SV=1 RNPH_VIBVU - Ribonuclease PH OS=Vibrio vulnificus GN=rph PE=3 SV=1	276.0	[0..1]	[237..1]
RNPH_PSEPF - Ribonuclease PH OS=Pseudomonas fluorescens (strain Pf0-1) GN=rph PE=3 SV=1	276.0	[0..2]	[237..3]
gi\|71733440, gi\|... - gi\|71733440\|ref\|YP_272506.1\| ribonuclease PH [Pseudomonas syringae pv. phaseolicola 1448A], gi\|71553...	276.0	[0..2]	[237..57]

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Predicted Domain #1

Region A:
Residues: [1-237]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MRPSKRAANE LRPLSFTTQF TRYAEGSVLV TLGNTKVICN ASIVEGVPRF LKNSEQGWLT  60
   61 AEYGMLPRST HSRMDREASR GKQGGRTVEI QRLIGRSLRA ALDLKLLGPY TITIDCDVIQ 120
  121 ADGGTRTAAI NGSCIAMIEA LRHLQRKGIL QTDPLKHKVA AVSVGIYKGV PVLDLDYAED 180
  181 SNAHTDMNVV MTDNDAFIEI QGTAEGDAFH AKELDALINL ARHGIKQIIE KQQEALS

[Run NCBI BLAST on this sequence.]

Detection Method:	PSI-BLAST
Confidence:	76.221849
Match:	1r6lA
Description:	Crystal Structure Of The tRNA Processing Enzyme Rnase pH From Pseudomonas Aeruginosa
Matching Structure (courtesy of the PDB):

Predicted functions:

Term	Confidence	Notes
ribonuclease activity	2.56399046328775	bayes_pls_golite062009
polyribonucleotide nucleotidyltransferase activity	1.91194827528589	bayes_pls_golite062009
catalytic activity	1.24889475603062	bayes_pls_golite062009
hydrolase activity	1.07767181032042	bayes_pls_golite062009
exoribonuclease activity	0.98086935928487	bayes_pls_golite062009
exoribonuclease activity, producing 5'-phosphomonoesters	0.92844426728299	bayes_pls_golite062009
peptidase activity	0.251251352515662	bayes_pls_golite062009

TMHMM	2.0c	PSIPRED	v2.61
SignalP	3.0	COILS	1999
DISOPRED	v0.1	NCBI nr	06/2007
PSI-BLAST	2.2.18	FFAS	ffas03
PDB	06/2007	Pfam	22
HMMER	2.3.2

View Structure Prediction Details

Top Sequence Alignment Hits

Predicted functions: