YRC Public Data Repository - Protein Structure Prediction

Protein:	RPIA_COXBU
Organism:	Coxiella burnetii RSA 493
Length:	220 amino acids
Reference:	Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16

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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for RPIA_COXBU.

Description	E-value	Query Range	Subject Range
RPIA_NITEU - Ribose-5-phosphate isomerase A OS=Nitrosomonas europaea GN=rpiA PE=3 SV=1 RPIA_NITEU - Ribose-5-phosphate isomerase A OS=Nitrosomonas europaea (strain ATCC 19718 / NBRC 14298) GN=rpiA PE=...	257.0	[0..1]	[218..1]
RPIA_SHEPC - Ribose-5-phosphate isomerase A OS=Shewanella putrefaciens (strain CN-32 / ATCC BAA-453) GN=rpiA PE=3...	254.0	[0..1]	[220..1]
RPIA_SHESW - Ribose-5-phosphate isomerase A OS=Shewanella sp. (strain W3-18-1) GN=rpiA PE=3 SV=1	254.0	[0..1]	[220..1]
gi\|114308819, gi... - gi\|71550684\|ref\|ZP_00670776.1\| Ribose 5-phosphate isomerase [Nitrosomonas eutropha C71], gi\|71484115...	252.0	[0..1]	[218..23]
gi\|94426307, gi\|... - gi\|94501489\|ref\|ZP_01308007.1\| ribose 5-phosphate isomerase A [Oceanobacter sp. RED65], gi\|94426307\|...	252.0	[0..1]	[220..1]
gi\|24114166, gi\|... - ref\|NP_708676.1\| ribose-5-phosphate isomerase, constitutive [Shigella flexneri 2a str. 301], gb\|AAN... gi\|26109738, gi\|... - gi\|26249330\|ref\|NP_755370.1\| ribose-5-phosphate isomerase A [Escherichia coli CFT073], gi\|26109738\|g... gi\|91212293, gi\|... - gi\|91212293\|ref\|YP_542279.1\| ribose-5-phosphate isomerase A [Escherichia coli UTI89], gi\|91073867\|gb... gi\|226899478, gi... - gi\|237706438\|ref\|ZP_04536919.1\| ribose-5-phosphate isomerase A [Escherichia sp. 3_2_53FAA], gi\|22689... gi\|226839585, gi... - gi\|254037961\|ref\|ZP_04872019.1\| ribose-5-phosphate isomerase A [Escherichia sp. 1_1_43], gi\|22683958...	251.0	[0..1]	[219..25]
RPIA_SHELP - Ribose-5-phosphate isomerase A OS=Shewanella loihica (strain ATCC BAA-1088 / PV-4) GN=rpiA PE=3 SV=1	251.0	[0..1]	[218..1]
RPIA_SHEB5 - Ribose-5-phosphate isomerase A OS=Shewanella baltica (strain OS155 / ATCC BAA-1091) GN=rpiA PE=3 SV=... RPIA_SHEB2 - Ribose-5-phosphate isomerase A OS=Shewanella baltica (strain OS223) GN=rpiA PE=3 SV=1 RPIA_SHEB9 - Ribose-5-phosphate isomerase A OS=Shewanella baltica (strain OS195) GN=rpiA PE=3 SV=1	251.0	[0..1]	[220..1]
gi\|90580302, gi\|... - gi\|90580302\|ref\|ZP_01236109.1\| ribose-5-phosphate isomerase A [Vibrio angustum S14], gi\|90438604\|gb\|...	251.0	[0..1]	[219..1]
RPIA_PSEE4 - Ribose-5-phosphate isomerase A OS=Pseudomonas entomophila (strain L48) GN=rpiA PE=3 SV=1 gi\|95113140 - gi\|95113140\|emb\|CAK17868.1\| ribose 5-phosphate isomerase [Pseudomonas entomophila L48]	250.0	[0..1]	[220..1]

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Predicted Domain #1

Region A:
Residues: [1-220]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MSKNELKKAA AMEAIQFVKN VNIVGVGTGS TVNYFIDALA EIKHQIEGAV ASSVATENRL  60
   61 KEHRIPVVDL NSVSNVDVYV DGADEFNKHF YLTKGGGGAL TREKIIAAAA KRFICIVDES 120
  121 KQVDVLGQFP LPIEVIPMAR SFVAREIVKL KGDPVYRQGF TTDNGNVILD IHNLTILNPV 180
  181 ELEAILNNIP GVIANGLFAQ QPADDLLIGT PAGVQLHHRK

[Run NCBI BLAST on this sequence.]

Detection Method:	PSI-BLAST
Confidence:	66.522879
Match:	1ks2A
Description:	D-ribose-5-phosphate isomerase (RpiA), catalytic domain; D-ribose-5-phosphate isomerase (RpiA), lid domain
Matching Structure (courtesy of the PDB):

Predicted functions:

Term	Confidence	Notes
ribose-5-phosphate isomerase activity	2.23318567990318	bayes_pls_golite062009
6-phosphogluconolactonase activity	1.97756803122763	bayes_pls_golite062009
intramolecular oxidoreductase activity	0.61058174487002	bayes_pls_golite062009
catalytic activity	0.424959044318554	bayes_pls_golite062009
nucleic acid binding	0.281224782944976	bayes_pls_golite062009
binding	0.228090098582514	bayes_pls_golite062009
glucosamine-6-phosphate deaminase activity	0.111185777194415	bayes_pls_golite062009
intramolecular oxidoreductase activity, interconverting aldoses and ketoses	0.075853172283603	bayes_pls_golite062009

TMHMM	2.0c	PSIPRED	v2.61
SignalP	3.0	COILS	1999
DISOPRED	v0.1	NCBI nr	06/2007
PSI-BLAST	2.2.18	FFAS	ffas03
PDB	06/2007	Pfam	22
HMMER	2.3.2

View Structure Prediction Details

Top Sequence Alignment Hits

Predicted functions: