YRC Public Data Repository - Protein Structure Prediction

Protein:	HPRT_ENTFA
Organism:	Enterococcus faecalis V583
Length:	181 amino acids
Reference:	Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16

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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for HPRT_ENTFA.

Description	E-value	Query Range	Subject Range
gi\|224500330 - gi\|224500330\|ref\|ZP_03668679.1\| hypothetical protein LmonF1_11939 [Listeria monocytogenes Finland 19... gi\|224503461 - gi\|224503461\|ref\|ZP_03671768.1\| hypothetical protein LmonFR_13287 [Listeria monocytogenes FSL R2-561... gi\|126941298, gi... - gi\|254900996\|ref\|ZP_05260920.1\| hypothetical protein LmonJ_14318 [Listeria monocytogenes J0161], gi\|... gi\|254913936, gi... - gi\|254913936\|ref\|ZP_05263948.1\| hypothetical protein LmonJ2_14108 [Listeria monocytogenes J2818], gi... gi\|133733948, gi... - gi\|254938274\|ref\|ZP_05269971.1\| hypothetical protein LmonF6_14141 [Listeria monocytogenes F6900], gi... gi\|47014358, gi\|... - gi\|47097258\|ref\|ZP_00234818.1\| conserved hypothetical protein/hypoxanthine phosphoribosyltransferase... TILS_LISMO - Bifunctional protein TilS/HprT OS=Listeria monocytogenes serovar 1/2a (strain ATCC BAA-679 / EGD-e) ... TILS_LISMO - Bifunctional protein tilS/hprT OS=Listeria monocytogenes GN=tilS/hprT PE=3 SV=1	164.0	[0..2]	[179..470]
TILS_LISIN - Bifunctional protein TilS/HprT OS=Listeria innocua serovar 6a (strain CLIP 11262) GN=tilS/hprT PE=3 ... TILS_LISIN - Bifunctional protein tilS/hprT OS=Listeria innocua GN=tilS/hprT PE=3 SV=1	164.0	[0..2]	[179..470]
TILS_LISMF - Bifunctional protein TilS/HprT OS=Listeria monocytogenes serotype 4b (strain F2365) GN=tilS/hprT PE=...	163.0	[0..2]	[179..470]
gi\|226222848, gi... - gi\|226222848\|ref\|YP_002756955.1\| hypothetical protein Lm4b_00217 [Listeria monocytogenes Clip81459],... gi\|47018468, gi\|... - gi\|47093161\|ref\|ZP_00230936.1\| conserved hypothetical protein/hypoxanthine phosphoribosyltransferase... gi\|21667249 - gi\|21667249\|gb\|AAM74001.1\|AF467001_2 YacA/HprT-like protein [Listeria monocytogenes] gi\|153200654, gi... - gi\|254933059\|ref\|ZP_05266418.1\| hypothetical protein LmonH_11532 [Listeria monocytogenes HPB2262], g...	163.0	[0..2]	[179..470]
gi\|116077257, gi... - gi\|116516681\|ref\|YP_815435.1\| hypoxanthine-guanine phosphoribosyltransferase [Streptococcus pneumoni... gi\|225853623, gi... - gi\|225853623\|ref\|YP_002735135.1\| hypoxanthine phosphoribosyltransferase [Streptococcus pneumoniae JJ... gi\|221230960, gi... - gi\|221230960\|ref\|YP_002510112.1\| hypoxanthine-guanine phosphoribosyltransferase [Streptococcus pneum... HPRT_STRR6 - Hypoxanthine-guanine phosphoribosyltransferase OS=Streptococcus pneumoniae (strain ATCC BAA-255 / R6... HPRT_STRPN - Hypoxanthine-guanine phosphoribosyltransferase OS=Streptococcus pneumoniae GN=hpt PE=3 SV=1 HPRT_STRPN - Hypoxanthine-guanine phosphoribosyltransferase OS=Streptococcus pneumoniae serotype 4 (strain ATCC B... gi\|147762895, gi... - gi\|149013372\|ref\|ZP_01834081.1\| hypoxanthine phosphoribosyltransferase [Streptococcus pneumoniae SP1... gi\|148993573, gi... - gi\|148993573\|ref\|ZP_01823044.1\| hypoxanthine phosphoribosyltransferase [Streptococcus pneumoniae SP9... gi\|148988916, gi... - gi\|148988916\|ref\|ZP_01820331.1\| hypoxanthine phosphoribosyltransferase [Streptococcus pneumoniae SP6... gi\|168484296, gi... - gi\|172042419\|gb\|EDT50465.1\| hypoxanthine phosphoribosyltransferase [Streptococcus pneumoniae CDC1873... gi\|147923333, gi... - gi\|148984556\|ref\|ZP_01817844.1\| hypoxanthine phosphoribosyltransferase [Streptococcus pneumoniae SP3... gi\|168493988, gi... - gi\|183575891\|gb\|EDT96419.1\| hypoxanthine phosphoribosyltransferase [Streptococcus pneumoniae CDC3059... gi\|168489347, gi... - gi\|183572298\|gb\|EDT92826.1\| hypoxanthine phosphoribosyltransferase [Streptococcus pneumoniae SP195],... gi\|194397408, gi... - gi\|194397408\|ref\|YP_002036733.1\| hypoxanthine-guanine phosphoribosyltransferase [Streptococcus pneum... gi\|182628315, gi... - gi\|182682981\|ref\|YP_001834728.1\| hypoxanthine-guanine phosphoribosyltransferase [Streptococcus pneum...	156.0	[0..1]	[180..1]
gi\|87161299\|ref\|... - hypoxanthine phosphoribosyltransferase [Staphylococcus aureus subsp. aureus USA300], hypoxanthine ph... gi\|87161299, gi\|... - gi\|87161299\|ref\|YP_493197.1\| hypoxanthine phosphoribosyltransferase [Staphylococcus aureus subsp. au...	154.0	[0..1]	[180..4]
gi\|116626985, gi... - gi\|62527121\|ref\|ZP_00388415.1\| COG0634: Hypoxanthine-guanine phosphoribosyltransferase [Streptococcu... HPRT_STRT2 - Hypoxanthine-guanine phosphoribosyltransferase OS=Streptococcus thermophilus (strain ATCC BAA-250 / ... gi\|55736099, gi\|... - gb\|AAV61630.1\| hypoxantine-guanine phosphorybosyltransferase [Streptococcus thermophilus CNRZ1066],... HPRT_STRT1 - Hypoxanthine-guanine phosphoribosyltransferase OS=Streptococcus thermophilus (strain CNRZ 1066) GN=h...	151.0	[0..1]	[178..1]
HPRT_STRA3 - Hypoxanthine-guanine phosphoribosyltransferase OS=Streptococcus agalactiae serotype III (strain NEM3... HPRT_STRA3 - Hypoxanthine-guanine phosphoribosyltransferase OS=Streptococcus agalactiae serotype III GN=hpt PE=3 ... HPRT_STRA5 - Hypoxanthine-guanine phosphoribosyltransferase OS=Streptococcus agalactiae serotype V GN=hpt PE=3 SV... gi\|76586667, gi\|... - gi\|76797987\|ref\|ZP_00780246.1\| hypoxanthine phosphoribosyltransferase [Streptococcus agalactiae 18RS... HPRT_STRA5 - Hypoxanthine-guanine phosphoribosyltransferase OS=Streptococcus agalactiae serotype V (strain ATCC B... gi\|76563535, gi\|... - gi\|76788478\|ref\|YP_328741.1\| hypoxanthine-guanine phosphoribosyltransferase [Streptococcus agalactia... gi\|77405623, gi\|... - gi\|77405623\|ref\|ZP_00782712.1\| hypoxanthine phosphoribosyltransferase [Streptococcus agalactiae H36B... gi\|77407711, gi\|... - gi\|77407711\|ref\|ZP_00784466.1\| hypoxanthine phosphoribosyltransferase [Streptococcus agalactiae COH1... gi\|77411298, gi\|... - gi\|77411298\|ref\|ZP_00787647.1\| hypoxanthine phosphoribosyltransferase [Streptococcus agalactiae CJB1... gi\|77414476, gi\|... - gi\|77414476\|ref\|ZP_00790626.1\| hypoxanthine phosphoribosyltransferase [Streptococcus agalactiae 515]...	151.0	[0..1]	[179..1]
gi\|269202130\|ref... - hypoxanthine phosphoribosyltransferase [Staphylococcus aureus subsp. aureus ED98] gi\|90426891, gi\|... - gi\|90584031\|ref\|ZP_01239777.1\| Hypoxanthine phosphoribosyl transferase [Staphylococcus aureus subsp.... gi\|82655748, gi\|... - gi\|82750217\|ref\|YP_415958.1\| hypoxanthine-guanine phosphoribosyltransferase [Staphylococcus aureus R... HPRT_STAAM - Hypoxanthine-guanine phosphoribosyltransferase OS=Staphylococcus aureus (strain Mu50 / ATCC 700699) ... HPRT_STAAN - Hypoxanthine-guanine phosphoribosyltransferase OS=Staphylococcus aureus (strain N315) GN=hpt PE=1 SV... gi\|255005303 - gi\|255005303\|ref\|ZP_05143904.2\| hypoxanthine phosphoribosyltransferase [Staphylococcus aureus subsp.... HPRT_STAAW - Hypoxanthine-guanine phosphoribosyltransferase OS=Staphylococcus aureus (strain MW2) GN=hpt PE=3 SV=... gi\|253315221 - gi\|253315221\|ref\|ZP_04838434.1\| hypoxanthine phosphoribosyltransferase [Staphylococcus aureus subsp.... gi\|90586963, gi\|... - gi\|90586963\|ref\|ZP_01242646.1\| Hypoxanthine phosphoribosyl transferase [Staphylococcus aureus subsp.... gi\|221138559 - gi\|221138559\|ref\|ZP_03563361.1\| hypoxanthine phosphoribosyltransferase [Staphylococcus aureus subsp.... gi\|221142298 - gi\|221142298\|ref\|ZP_03566791.1\| hypoxanthine phosphoribosyltransferase [Staphylococcus aureus subsp.... HPRT_STAAC - Hypoxanthine-guanine phosphoribosyltransferase OS=Staphylococcus aureus (strain COL) GN=hpt PE=3 SV=... gi\|88194270, gi\|... - gi\|88194270\|ref\|YP_499062.1\| hypoxanthine phosphoribosyltransferase [Staphylococcus aureus subsp. au... gi\|156720973, gi... - gi\|156978838\|ref\|YP_001441097.1\| hypoxanthine-guanine phosphoribosyltransferase homologue [Staphyloc... HPRT_STAAS - Hypoxanthine-guanine phosphoribosyltransferase OS=Staphylococcus aureus (strain MSSA476) GN=hpt PE=3... gi\|25286884 - pir\|\|G89817 hypothetical protein SA0468 [imported] - Staphylococcus aureus (strain N315) HPRT_STAAR - Hypoxanthine-guanine phosphoribosyltransferase OS=Staphylococcus aureus (strain MRSA252) GN=hpt PE=3...	151.0	[0..2]	[180..1]
gi\|69245449, gi\|... - gi\|69245449\|ref\|ZP_00603444.1\| Hypoxanthine phosphoribosyl transferase [Enterococcus faecium DO], gi... gi\|48825693 - ref\|ZP_00286934.1\| COG0634: Hypoxanthine-guanine phosphoribosyltransferase [Enterococcus faecium]	150.0	[0..1]	[181..1]

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Predicted Domain #1

Region A:
Residues: [1-181]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MIEKDIEKVL ISKEEILAKS AELGKQLTEE YQGKNPLVVG ILKGAVPFMA DLTREINTYL  60
   61 ELDFMDVSSY GNATVSSGEV KIVKDLDTNV EGRHILIVED IIDSGRTLAY LVDLFRYRKA 120
  121 ASVKIVTLLD KPEGRVVDIK ADYVGFDVPN EFVVGYGLDY AETYRNLPYI GVLKPEVYES 180
  181 N

[Run NCBI BLAST on this sequence.]

Detection Method:	PSI-BLAST
Confidence:	33.522879
Match:	1r3uA
Description:	Crystal Structure of Hypoxanthine-Guanine Phosphoribosyltransferase from Thermoanaerobacter tengcongensis
Matching Structure (courtesy of the PDB):

Predicted functions:

Term	Confidence	Notes
adenine phosphoribosyltransferase activity	4.07252508868782	bayes_pls_golite062009
transferase activity, transferring glycosyl groups	3.91023158228049	bayes_pls_golite062009
hypoxanthine phosphoribosyltransferase activity	3.89356447922614	bayes_pls_golite062009
transferase activity	2.73727660668741	bayes_pls_golite062009
nucleobase binding	2.70671399975507	bayes_pls_golite062009
purine binding	2.63033967717893	bayes_pls_golite062009
transferase activity, transferring pentosyl groups	2.53679639481311	bayes_pls_golite062009
uracil phosphoribosyltransferase activity	2.36237864658341	bayes_pls_golite062009
catalytic activity	2.30431811394775	bayes_pls_golite062009
amidophosphoribosyltransferase activity	1.6596316647688	bayes_pls_golite062009
ribose phosphate diphosphokinase activity	1.51875493459374	bayes_pls_golite062009
protein binding	1.02514711359042	bayes_pls_golite062009
adenine binding	0.817887117933035	bayes_pls_golite062009
diphosphotransferase activity	0.749909396904601	bayes_pls_golite062009
binding	0.644392905117932	bayes_pls_golite062009
nucleic acid binding	0.439453264070391	bayes_pls_golite062009
transcription regulator activity	0.369893745269311	bayes_pls_golite062009
DNA binding	0.275043319532312	bayes_pls_golite062009
orotate phosphoribosyltransferase activity	0.148898393751978	bayes_pls_golite062009

TMHMM	2.0c	PSIPRED	v2.61
SignalP	3.0	COILS	1999
DISOPRED	v0.1	NCBI nr	06/2007
PSI-BLAST	2.2.18	FFAS	ffas03
PDB	06/2007	Pfam	22
HMMER	2.3.2

View Structure Prediction Details

Top Sequence Alignment Hits

Predicted functions: