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View Structure Prediction Details

Protein: HGNC:17151|MIM:6...
Organism: SPECIES UNKNOWN
Length: 252 amino acids
Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16



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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for HGNC:17151|MIM:6....

Description E-value Query
Range
Subject
Range
gi|114662327 - gi|114662327|ref|XP_001161833.1| PREDICTED: origin recognition complex subunit 6 isoform 4 [Pan trog...
0.0 [1..252] [1..252]
gi|109128387 - gi|109128387|ref|XP_001113625.1| PREDICTED: similar to origin recognition complex subunit 6 [Macaca ...
0.0 [1..252] [1..252]
ORC6_MOUSE - Origin recognition complex subunit 6 OS=Mus musculus GN=Orc6 PE=1 SV=1
9.0E-97 [1..252] [1..262]
ORC6_BOVIN - Origin recognition complex subunit 6 OS=Bos taurus GN=ORC6 PE=2 SV=1
3.0E-95 [1..252] [1..252]
gi|27658770, gi|... - gi|76096324|ref|NP_001028862.1| origin recognition complex, subunit 6 like [Rattus norvegicus], gi|7...
3.0E-95 [1..252] [1..262]
gi|73977476 - gi|73977476|ref|XP_539609.2| PREDICTED: similar to origin recognition complex subunit 6 [Canis famil...
2.0E-86 [1..252] [1..252]
gi|33989468, gi|... - gi|47086695|ref|NP_997836.1| origin recognition complex, subunit 6 homolog-like [Danio rerio], gi|41...
2.0E-77 [1..247] [1..252]

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Predicted Domain #1
Region A:
Residues: [1-252]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MGSELIGRLA PRLGLAEPDM LRKAEEYLRL SRVKCVGLSA RTTETSSAVM CLDLAASWMK  60
   61 CPLDRAYLIK LSGLNKETYQ SCLKSFECLL GLNSNIGIRD LAVQFSCIEA VNMASKILKS 120
  121 YESSLPQTQQ VDLDLSRPLF TSAALLSACK ILKLKVDKNK MVATSGVKKA IFDRLCKQLE 180
  181 KIGQQVDREP GDVATPPRKR KKIVVEAPAK EMEKVEEMPH KPQKDEDLTQ DYEEWKRKIL 240
  241 ENAASAQKAT AE

[Run NCBI BLAST on this sequence.]

Detection Method: FFAS03
Confidence: 1.41
Match: 1tfbA
Description: NMR STUDIES OF HUMAN GENERAL TRANSCRIPTION FACTOR TFIIB: DYNAMICS AND INTERACTION WITH VP16 ACTIVATION DOMAIN, 20 STRUCTURES
Matching Structure (courtesy of the PDB):

Predicted functions:

Term Confidence Notes
transcription regulator activity 2.75688185850223 bayes_pls_golite062009
binding 2.37916921859542 bayes_pls_golite062009
general RNA polymerase II transcription factor activity 2.37399236069363 bayes_pls_golite062009
nucleic acid binding 2.06743451505655 bayes_pls_golite062009
DNA binding 1.95321993038755 bayes_pls_golite062009
transcription repressor activity 1.41828738664896 bayes_pls_golite062009
cyclin-dependent protein kinase regulator activity 1.41497909264171 bayes_pls_golite062009
protein binding 1.37207701115974 bayes_pls_golite062009
transcription factor activity 1.22628491144894 bayes_pls_golite062009
protein kinase regulator activity 1.21941169140389 bayes_pls_golite062009
kinase regulator activity 1.18590233040331 bayes_pls_golite062009
RNA polymerase II transcription factor activity 0.962670695182671 bayes_pls_golite062009
transcription factor binding 0.655253705928308 bayes_pls_golite062009
enzyme regulator activity 0.461517963237846 bayes_pls_golite062009
transcription coactivator activity 0.0843751392410543 bayes_pls_golite062009
transcription activator activity 0.0606514459376675 bayes_pls_golite062009

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