YRC Public Data Repository - Protein Structure Prediction

Protein:	gi\|26110725, gi\|...
Organism:	Escherichia coli CFT073
Length:	226 amino acids
Reference:	Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16

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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for gi|26110725, gi|....

Description	E-value	Query Range	Subject Range
gi\|221236171, gi... - gi\|221236171\|ref\|YP_002518608.1\| spermidine/putrescine transport ATP-binding protein potA [Caulobact... gi\|25384753 - pir\|\|D87637 hypothetical protein CC3134 [imported] - Caulobacter crescentus gi\|16127364, gi\|... - gi\|16127364\|ref\|NP_421928.1\| spermidine/putrescine ABC transporter, ATP-binding protein [Caulobacter...	228.0	[0..2]	[221..17]
gi\|27382307, gi\|... - gi\|27382307\|ref\|NP_773836.1\| ABC transporter ATP-binding protein [Bradyrhizobium japonicum USDA 110]...	225.0	[0..3]	[222..27]
gi\|113726386, gi... - gi\|150395538\|ref\|YP_001326005.1\| spermidine/putrescine ABC transporter ATPase subunit [Sinorhizobium...	222.0	[0..2]	[221..25]
gi\|254695755 - gi\|254695755\|ref\|ZP_05157583.1\| Uridine kinase [Brucella abortus bv. 3 str. Tulya] gi\|254698719 - gi\|254698719\|ref\|ZP_05160547.1\| Uridine kinase [Brucella abortus bv. 2 str. 86/8/59] gi\|237787804, gi... - gi\|237816991\|ref\|ZP_04595983.1\| Spermidine/putrescine import ATP-binding protein potA [Brucella abor... gi\|254690936 - gi\|254690936\|ref\|ZP_05154190.1\| Uridine kinase [Brucella abortus bv. 6 str. 870] FBPC_BRUA2 - Fe(3+) ions import ATP-binding protein FbpC OS=Brucella abortus (strain 2308) GN=fbpC PE=3 SV=1 FBPC_BRUAB - Fe(3+) ions import ATP-binding protein FbpC OS=Brucella abortus GN=fbpC PE=3 SV=1 gi\|254705796 - gi\|254705796\|ref\|ZP_05167624.1\| Uridine kinase [Brucella pinnipedialis M163/99/10] FBPC_BRUAB - Fe(3+) ions import ATP-binding protein FbpC OS=Brucella abortus biovar 1 (strain 9-941) GN=fbpC PE=3... gi\|189022693, gi... - gi\|189022693\|ref\|YP_001932434.1\| Uridine kinase [Brucella abortus S19], gi\|189021267\|gb\|ACD73988.1\| ... gi\|254732164 - gi\|254732164\|ref\|ZP_05190742.1\| Uridine kinase [Brucella abortus bv. 4 str. 292]	222.0	[0..2]	[221..11]
gi\|28202474, gi\|... - gi\|28210039\|ref\|NP_780983.1\| iron(III)-transport ATP-binding protein sfuC [Clostridium tetani E88], ...	221.0	[0..11]	[221..24]
POTA_DESAG - Spermidine/putrescine import ATP-binding protein PotA OS=Desulfovibrio alaskensis (strain G20) GN=po...	221.0	[0..1]	[222..7]
gi\|78519438, gi\|... - gi\|78693883\|ref\|ZP_00858397.1\| Spermidine/putrescine ABC transporter ATP-binding subunit [Bradyrhizo...	220.0	[0..5]	[222..29]
gi\|48835579 - ref\|ZP_00292578.1\| COG3842: ABC-type spermidine/putrescine transport systems, ATPase components [The... POTA_THEFY - Spermidine/putrescine import ATP-binding protein PotA OS=Thermobifida fusca (strain YX) GN=potA PE=3...	220.0	[0..3]	[221..29]
gi\|15073645 - gi\|15073645\|emb\|CAC45287.1\| Probable putrescine transport ATP-binding protein [Sinorhizobium melilot... gi\|15964468 - gi\|15964468\|ref\|NP_384821.1\| putrescine ABC transporter ATP-binding protein [Sinorhizobium meliloti ...	220.0	[0..4]	[221..28]

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Predicted Domain #1

Region A:
Residues: [1-226]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MYNKLVCRLY FANHIRKILM AQGTLYIVSA PSGAGKSSLI QALLKTQPLY DTQVSVSHTT  60
   61 RQPRPGEVHG EHYFFVNHDE FKEMISRDAF LEHAEVFGNY YGTSREAIEQ VLATGVDVFL 120
  121 DIDWQGAQQI RQKMPHARSI FILPPSKIEL DRRLRGRGQD SEEVIAKRMA QAVAEMSHYA 180
  181 EYDYLIVNDD FDTALTDLKT IIRAERLRMS RQKQRHDALI SKLLAD

[Run NCBI BLAST on this sequence.]

Detection Method:	PSI-BLAST
Confidence:	48.69897
Match:	1s96A
Description:	The 2.0 A X-ray structure of Guanylate Kinase from E.coli
Matching Structure (courtesy of the PDB):

Predicted functions:

Term	Confidence	Notes
nucleobase, nucleoside, nucleotide kinase activity	3.66392587433723	bayes_pls_golite062009
hydrogen ion transporting ATP synthase activity, rotational mechanism	3.47528445676761	bayes_pls_golite062009
hydrogen ion transmembrane transporter activity	2.55741461337855	bayes_pls_golite062009
substrate-specific transporter activity	2.54103332067513	bayes_pls_golite062009
binding	2.44689197844883	bayes_pls_golite062009
monovalent inorganic cation transmembrane transporter activity	2.40650518173039	bayes_pls_golite062009
nucleotide kinase activity	2.24094813695083	bayes_pls_golite062009
phosphotransferase activity, phosphate group as acceptor	1.96697952975573	bayes_pls_golite062009
substrate-specific transmembrane transporter activity	1.92480060698169	bayes_pls_golite062009
ion transmembrane transporter activity	1.69194088788064	bayes_pls_golite062009
inorganic cation transmembrane transporter activity	1.60317778681063	bayes_pls_golite062009
cation transmembrane transporter activity	1.48327844851166	bayes_pls_golite062009
nucleic acid binding	1.08697924060619	bayes_pls_golite062009
catalytic activity	1.00104173493322	bayes_pls_golite062009
DNA binding	0.702147676354075	bayes_pls_golite062009
adenylate kinase activity	0.447752711852745	bayes_pls_golite062009
transcription regulator activity	0.287777990975748	bayes_pls_golite062009
helicase activity	0.0775311459068899	bayes_pls_golite062009
protein binding	0.071010918255742	bayes_pls_golite062009

TMHMM	2.0c	PSIPRED	v2.61
SignalP	3.0	COILS	1999
DISOPRED	v0.1	NCBI nr	06/2007
PSI-BLAST	2.2.18	FFAS	ffas03
PDB	06/2007	Pfam	22
HMMER	2.3.2

View Structure Prediction Details

Top Sequence Alignment Hits

Predicted functions: