YRC Public Data Repository - Protein Structure Prediction

Protein:	PYRC_SHEON
Organism:	Shewanella oneidensis MR-1
Length:	343 amino acids
Reference:	Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16

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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for PYRC_SHEON.

Description	E-value	Query Range	Subject Range
gi\|195991527, gi... - gi\|196035878\|ref\|ZP_03103280.1\| dihydroorotase [Bacillus cereus W], gi\|195991527\|gb\|EDX55493.1\| dihy... gi\|190565763, gi... - gi\|190565763\|ref\|ZP_03018682.1\| dihydroorotase [Bacillus anthracis Tsiankovskii-I], gi\|190562682\|gb\|... PYRC_BACC0 - Dihydroorotase OS=Bacillus cereus (strain AH820) GN=pyrC PE=3 SV=1 gi\|30263891, gi\|... - gi\|30263891\|ref\|NP_846268.1\| dihydroorotase [Bacillus anthracis str. Ames], gi\|30258535\|gb\|AAP27754.... gi\|21401873, gi\|... - gi\|65321216\|ref\|ZP_00394175.1\| COG0044: Dihydroorotase and related cyclic amidohydrolases [Bacillus ... PYRC_BACAC - Dihydroorotase OS=Bacillus anthracis (strain CDC 684 / NRRL 3495) GN=pyrC PE=3 SV=1 PYRC_BACAA - Dihydroorotase OS=Bacillus anthracis (strain A0248) GN=pyrC PE=3 SV=1 gi\|254721421 - gi\|254721421\|ref\|ZP_05183210.1\| dihydroorotase [Bacillus anthracis str. A1055] gi\|167510936, gi... - gi\|167641156\|ref\|ZP_02399411.1\| dihydroorotase [Bacillus anthracis str. A0193], gi\|167510936\|gb\|EDR8... gi\|254735928 - gi\|254735928\|ref\|ZP_05193634.1\| dihydroorotase [Bacillus anthracis str. Western North America USA615... gi\|165872277, gi... - gi\|165872277\|ref\|ZP_02216914.1\| dihydroorotase [Bacillus anthracis str. A0488], gi\|164711953\|gb\|EDR1... gi\|254751014 - gi\|254751014\|ref\|ZP_05203053.1\| dihydroorotase [Bacillus anthracis str. Vollum] gi\|49186738, gi\|... - gi\|49186738\|ref\|YP_029990.1\| dihydroorotase [Bacillus anthracis str. Sterne], gi\|49180665\|gb\|AAT5604... gi\|172080423, gi... - gi\|177654912\|ref\|ZP_02936629.1\| dihydroorotase [Bacillus anthracis str. A0174], gi\|172080423\|gb\|EDT6... gi\|254756679 - gi\|254756679\|ref\|ZP_05208708.1\| dihydroorotase [Bacillus anthracis str. Australia 94] gi\|47504468, gi\|... - gi\|47529320\|ref\|YP_020669.1\| dihydroorotase [Bacillus anthracis str. 'Ames Ancestor'], gi\|47504468\|g... gi\|170126290, gi... - gi\|170708805\|ref\|ZP_02899241.1\| dihydroorotase [Bacillus anthracis str. A0389], gi\|170126290\|gb\|EDS9... PYRC_BACAN - Dihydroorotase OS=Bacillus anthracis GN=pyrC PE=1 SV=1	325.0	[0..3]	[342..49]
PYRC_CUPNH - Dihydroorotase OS=Cupriavidus necator (strain ATCC 17699 / H16 / DSM 428 / Stanier 337) GN=pyrC PE=3...	324.0	[0..2]	[341..3]
gi\|224501362 - gi\|224501362\|ref\|ZP_03669669.1\| dihydroorotase [Listeria monocytogenes FSL R2-561] gi\|47015090, gi\|... - gi\|47096558\|ref\|ZP_00234148.1\| dihydroorotase, multifunctional complex type [Listeria monocytogenes ... PYRC_LISMO - Dihydroorotase OS=Listeria monocytogenes serovar 1/2a (strain ATCC BAA-679 / EGD-e) GN=pyrC PE=3 SV=... gi\|254899466, gi... - gi\|254899466\|ref\|ZP_05259390.1\| dihydroorotase [Listeria monocytogenes J0161], gi\|153183327\|ref\|ZP_0... gi\|153175068, gi... - gi\|254829167\|ref\|ZP_05233854.1\| dihydroorotase [Listeria monocytogenes FSL N3-165], gi\|153175068\|ref... gi\|133732517, gi... - gi\|254936722\|ref\|ZP_05268419.1\| dihydroorotase [Listeria monocytogenes F6900], gi\|153179873\|ref\|ZP_0... PYRC_LISMO - Dihydroorotase OS=Listeria monocytogenes GN=pyrC PE=3 SV=1 gi\|254912395 - gi\|254912395\|ref\|ZP_05262407.1\| dihydroorotase [Listeria monocytogenes J2818]	324.0	[0..3]	[342..48]
PYRC_BACHK - Dihydroorotase OS=Bacillus thuringiensis subsp. konkukian GN=pyrC PE=3 SV=1 PYRC_BACHK - Dihydroorotase OS=Bacillus thuringiensis subsp. konkukian (strain 97-27) GN=pyrC PE=3 SV=1	323.0	[0..3]	[342..49]
gi\|196047421, gi... - gi\|196047421\|ref\|ZP_03114633.1\| dihydroorotase [Bacillus cereus 03BB108], gi\|196021729\|gb\|EDX60424.1... PYRC_BACAH - Dihydroorotase OS=Bacillus thuringiensis (strain Al Hakam) GN=pyrC PE=3 SV=1 gi\|47553845, gi\|... - gi\|47569516\|ref\|ZP_00240196.1\| dihydroorotase [Bacillus cereus G9241], gi\|47553845\|gb\|EAL12216.1\| di... PYRC_BACCZ - Dihydroorotase OS=Bacillus cereus (strain ZK / E33L) GN=pyrC PE=3 SV=1 gi\|196030339, gi... - gi\|196038616\|ref\|ZP_03105924.1\| dihydroorotase [Bacillus cereus NVH0597-99], gi\|196030339\|gb\|EDX6893...	323.0	[0..3]	[342..49]
PYRC_BACC1 - Dihydroorotase OS=Bacillus cereus (strain ATCC 10987 / NRS 248) GN=pyrC PE=3 SV=1	323.0	[0..3]	[342..49]
PYRC_BACCL - Dihydroorotase OS=Bacillus caldolyticus GN=pyrC PE=3 SV=1	322.0	[0..3]	[342..50]
PYRC_GEOKA - Dihydroorotase OS=Geobacillus kaustophilus (strain HTA426) GN=pyrC PE=3 SV=1 PYRC_GEOKA - Dihydroorotase OS=Geobacillus kaustophilus GN=pyrC PE=3 SV=1	322.0	[0..3]	[342..51]
PYRC_LISIN - Dihydroorotase OS=Listeria innocua serovar 6a (strain CLIP 11262) GN=pyrC PE=3 SV=1 PYRC_LISIN - Dihydroorotase OS=Listeria innocua GN=pyrC PE=3 SV=1	322.0	[0..3]	[342..48]
PYRC_BACWK - Dihydroorotase OS=Bacillus weihenstephanensis (strain KBAB4) GN=pyrC PE=3 SV=1	322.0	[0..3]	[342..49]

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Predicted Domain #1

Region A:
Residues: [1-343]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MKTLTITRPD DWHIHLRDGA QLTDTVRDIS RYMGRAIVMP NLVPPAIDTE TALAYYDRIK  60
   61 ARVPAGSQFE PLMVLYLTDK TSPDEIRKAK ASGKVFAAKL YPAGATTNSD SGVTDLKNIY 120
  121 PALEAMQEVG MLFLVHGEVT DSSIDIFDRE RVFIENILSK IVTDFPNLKI VLEHITTKDA 180
  181 VDFVTQASDN VAATITAHHL LYNRNHMLAG GIRPHFYCLP ILKRNTHQQA LLAAAASGNK 240
  241 KFFLGTDSAP HAKDRKEAAC GCAGSYTAHA AIELYAEAFE SVNALDKLEA FASFNGPDFY 300
  301 NLPRNSDTIT LVKKAWDIPA SYPLGDTNVV PIRAGEQIDW QVE

[Run NCBI BLAST on this sequence.]

Detection Method:	PSI-BLAST
Confidence:	85.69897
Match:	1xgeA
Description:	Dihydroorotase from Escherichia coli: Loop Movement and Cooperativity between subunits
Matching Structure (courtesy of the PDB):

Predicted functions:

Term	Confidence	Notes
dihydroorotase activity	2.32070383330692	bayes_pls_golite062009
hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides	2.20489529944693	bayes_pls_golite062009
deaminase activity	1.79186203771221	bayes_pls_golite062009
catalytic activity	1.70199291046899	bayes_pls_golite062009
hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds	1.60895003474033	bayes_pls_golite062009
nucleic acid binding	0.629962267754185	bayes_pls_golite062009
hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amidines	0.573107361273483	bayes_pls_golite062009
transcription regulator activity	0.506159010274668	bayes_pls_golite062009
DNA binding	0.462348875991261	bayes_pls_golite062009
binding	0.459041534336076	bayes_pls_golite062009
hydrolase activity	0.24275130580417	bayes_pls_golite062009

TMHMM	2.0c	PSIPRED	v2.61
SignalP	3.0	COILS	1999
DISOPRED	v0.1	NCBI nr	06/2007
PSI-BLAST	2.2.18	FFAS	ffas03
PDB	06/2007	Pfam	22
HMMER	2.3.2

View Structure Prediction Details

Top Sequence Alignment Hits

Predicted functions: