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View Structure Prediction Details

Protein: gi|24374817, gi|...
Organism: Shewanella oneidensis MR-1
Length: 1171 amino acids
Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16



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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for gi|24374817, gi|....

Description E-value Query
Range
Subject
Range
gi|89949914, gi|... - gi|90020314|ref|YP_526141.1| response regulator receiver domain-containing protein [Saccharophagus d...
671.0 [0..9] [1170..4]
gi|29340236, gi|... - gi|29348332|ref|NP_811835.1| two-component system sensor histidine kinase/response regulator, hybrid...
663.0 [0..18] [1169..1]
gi|67931601, gi|... - gi|67931601|ref|ZP_00524760.1| Response regulator receiver:ATP-binding region, ATPase-like:Histidine...
644.0 [0..43] [1169..46]
gi|53715770, gi|... - gi|53715770|ref|YP_101762.1| two-component system sensor histidine kinase/response regulator hybrid ...
644.0 [0..18] [1170..1]
gi|60495135, gi|... - gi|60683701|ref|YP_213845.1| putative two-component system sensor kinase/response regulator fusion p...
642.0 [0..18] [1170..1]

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Predicted Domain #1
Region A:
Residues: [1-610]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MVRSNVGSQC YQKRLTLMSR CYYLSIFLVF WSFIVSAQAK AAYYPLAQQI SSENGLSQNV  60
   61 VLALEEDNYG RIWVGTQDGL NLINNNELLV FRRDQAEHRL SGTVITDLTL DQQGRLWVAS 120
  121 DVGLDYIDTT TLESHVITLN QSISHMLLHT EQTIFYLSSQ KLYQFQINTG QVQEVKLPEL 180
  181 FQIINTLGSY DEQHLLLIGP NGFGVLNLST GDVTPLQPDI PAGTYKASTI SAERIWISQM 240
  241 EQGLYSCNLQ GLDCRTYSKA NQKLPTNNIA QIYQQDTALF LATDKGIGRL DLITDKLEWI 300
  301 YPHSQNNAYQ ASRIARNLIP AKSGDIFVGT FNGLYRIPNT YKEVQAFNTG IGGYPSNQLA 360
  361 VNKVMLNGQE RLVIAQPDKL TLWTLDASIL RLYREYDYPQ GFVPTNLFVD GGDIYLSSLT 420
  421 NNNLILTPHN GAFTSLEERF AQLGNVQLFN MNQPQEDIRV FHLLTSMKVY QQRQNKWQLL 480
  481 WEKPFLTGSA TAEYWQGRLY VASYQNGLMS ASMDNDWQKP QQWQQHHGLG IAINLFAQKD 540
  541 KLYVLTANLG LFQVDSSSPI SITQVSSRDK LASQTLVCAI RDHNGQLILS SHKGLVIFDS 600
  601 QQESLIYLSS 

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 7.221849
Match: 2cn3A
Description: No description for 2cn3A was found.

Predicted Domain #2
Region A:
Residues: [611-805]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 LQGTHEQEFS QFSCGTLNNV PYFAGERGLT LVFDSQAIKS PAPQITWTHL DVDGLTYRLG  60
   61 SSGTGKLTAP EFIRLHFVAT PSDLPKQASY RYRIKSLSDE WVELKSSFIP MINLRPGSYQ 120
  121 VELESRDFSG RSSPIALATL EIAPGFWESS LAISLYIFIG LVVIALLVSH RIKADRSLLA 180
  181 LEVEKNRHQQ DYSRK

[Run NCBI BLAST on this sequence.]

Detection Method: FFAS03
Confidence: 2.11
Match: 1wfoA
Description: The eighth FN3 domain of human sidekick-2
Matching Structure (courtesy of the PDB):

Predicted functions:

Term Confidence Notes
binding 1.67334813055186 bayes_pls_golite062009
protein binding 1.30493021305349 bayes_pls_golite062009
signal transducer activity 1.27638082879581 bayes_pls_golite062009
molecular transducer activity 1.27638082879581 bayes_pls_golite062009
receptor activity 0.578624943275614 bayes_pls_golite062009
transmembrane receptor activity 0.509477493931933 bayes_pls_golite062009
catalytic activity 0.306113740875124 bayes_pls_golite062009
cytokine binding 0.0798365598476543 bayes_pls_golite062009

Predicted Domain #3
Region A:
Residues: [806-1044]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 LEHEVQIRTN ELAQKKEEAE EANTAKTRFI AAASHDLKHP IGLIRLQLEQ IEDNKLSYKI  60
   61 NTSLSFLEQL VSSIVELSRL DARVLVPQIS SFDLGIFIAK VAEEHLTLAQ SFRLNLMTDI 120
  121 KSDVWVASDS LLLRRVIDNI LSNAIKISDP DTSVSLSVCQ ERQHAVIEVI DQGPGMTQQM 180
  181 QAELFTPFKR WTSRYQGSGL GLSVVKGIAD LLGISLSIRS TLGEGTQFTL KLPLIDKPT

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 42.0
Match: 2c2aA
Description: Structure of the entire cytoplasmic portion of a sensor histidine kinase protein
Matching Structure (courtesy of the PDB):

Predicted Domain #4
Region A:
Residues: [1045-1171]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 FSHIEDEAAI FHLGIVEDDY EQLNHLCSSL MVRGIKVSGY RHAISLLQDK TAIFDAILSD  60
   61 IDIGTEQDGL AYLVEYRQRL TDAKPLIYMS GNPEAGLRIP SQTDLFFFSK PLKLGKLMWL 120
  121 LNQSKRK

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 25.221849
Match: 1mvoA
Description: PhoP receiver domain
Matching Structure (courtesy of the PDB):

Predicted functions:

Term Confidence Notes
two-component response regulator activity 7.02872640261738 bayes_pls_golite062009
signal transducer activity 4.51666042720644 bayes_pls_golite062009
molecular transducer activity 4.51666042720644 bayes_pls_golite062009
transcription regulator activity 3.44888100104099 bayes_pls_golite062009
protein histidine kinase activity 2.35011582062573 bayes_pls_golite062009
two-component sensor activity 2.32303301074957 bayes_pls_golite062009
phosphotransferase activity, nitrogenous group as acceptor 2.28838869071567 bayes_pls_golite062009
binding 1.22427537074115 bayes_pls_golite062009
DNA binding 1.11037597107903 bayes_pls_golite062009
protein kinase activity 1.00737355751913 bayes_pls_golite062009
nucleic acid binding 0.93151849951839 bayes_pls_golite062009
phosphotransferase activity, alcohol group as acceptor 0.811771244977462 bayes_pls_golite062009
kinase activity 0.725824770559857 bayes_pls_golite062009
transcription factor activity 0.62886970109503 bayes_pls_golite062009
transferase activity, transferring phosphorus-containing groups 0.476057209677045 bayes_pls_golite062009

YRC Informatics Platform - Version 3.0
Created and Maintained by: Michael Riffle