YRC Public Data Repository - Protein Structure Prediction

Protein:	gi\|24349151, gi\|...
Organism:	Shewanella oneidensis MR-1
Length:	498 amino acids
Reference:	Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16

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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for gi|24349151, gi|....

Description	E-value	Query Range	Subject Range
gi\|50287255, gi\|... - gi\|50287255\|ref\|XP_446057.1\| unnamed protein product [Candida glabrata], gi\|49525364\|emb\|CAG58981.1\|... gi\|49525364 - gi\|49525364\|emb\|CAG58981.1\| unnamed protein product [Candida glabrata]	242.0	[0..7]	[497..17]
gi\|23502768, gi\|... - gi\|23502768\|ref\|NP_698895.1\| dihydrolipoamide dehydrogenase [Brucella suis 1330], gi\|23348787\|gb\|AAN... gi\|254708909 - gi\|254708909\|ref\|ZP_05170720.1\| dihydrolipoamide dehydrogenase [Brucella pinnipedialis B2/94] gi\|254707554 - gi\|254707554\|ref\|ZP_05169382.1\| dihydrolipoamide dehydrogenase [Brucella pinnipedialis M163/99/10] gi\|254700562 - gi\|254700562\|ref\|ZP_05162390.1\| dihydrolipoamide dehydrogenase [Brucella suis bv. 5 str. 513] gi\|225616943, gi... - gi\|225628118\|ref\|ZP_03786153.1\| dihydrolipoamide dehydrogenase [Brucella ceti str. Cudo], gi\|2256169... gi\|254715982 - gi\|254715982\|ref\|ZP_05177793.1\| dihydrolipoamide dehydrogenase [Brucella ceti M13/05/1] gi\|254713664 - gi\|254713664\|ref\|ZP_05175475.1\| dihydrolipoamide dehydrogenase [Brucella ceti M644/93/1]	238.0	[0..13]	[496..3]
gi\|237788347, gi... - gi\|237816280\|ref\|ZP_04595273.1\| dihydrolipoamide dehydrogenase [Brucella abortus str. 2308 A], gi\|23... gi\|254690062 - gi\|254690062\|ref\|ZP_05153316.1\| dihydrolipoamide dehydrogenase [Brucella abortus bv. 6 str. 870] gi\|82700684 - gi\|82700684\|ref\|YP_415258.1\| dihydrolipoamide dehydrogenase [Brucella melitensis biovar Abortus 2308... gi\|82616785 - gi\|82616785\|emb\|CAJ11874.1\| Pyridine nucleotide-disulphide oxidoreductase, class-II:NAD binding site... gi\|62290772, gi\|... - gi\|62290772\|ref\|YP_222565.1\| dihydrolipoamide dehydrogenase [Brucella abortus bv. 1 str. 9-941], gi\|... gi\|254696175 - gi\|254696175\|ref\|ZP_05158003.1\| dihydrolipoamide dehydrogenase [Brucella abortus bv. 2 str. 86/8/59] gi\|254731093 - gi\|254731093\|ref\|ZP_05189671.1\| dihydrolipoamide dehydrogenase [Brucella abortus bv. 4 str. 292] gi\|189020559, gi... - gi\|189024987\|ref\|YP_001935755.1\| dihydrolipoamide dehydrogenase [Brucella abortus S19], gi\|189020559...	237.0	[0..13]	[496..3]
gi\|74016022, gi\|... - gi\|74016022\|ref\|ZP_00686649.1\| Dihydrolipoamide dehydrogenase [Burkholderia ambifaria AMMD], gi\|7261...	235.0	[0..10]	[497..2]
gi\|25284939 - pir\|\|AD3270 dihydrolipoamide dehydrogenase (EC 1.8.1.4) [imported] - Brucella melitensis (strain 16M... gi\|17982024, gi\|... - gi\|17986429\|ref\|NP_539063.1\| dihydrolipoamide dehydrogenase [Brucella melitensis 16M], gi\|17982024\|g...	235.0	[0..13]	[496..3]
gi\|67528998, gi\|... - gi\|67549683\|ref\|ZP_00427535.1\| Dihydrolipoamide dehydrogenase [Burkholderia vietnamiensis G4], gi\|67...	235.0	[0..10]	[497..2]
gi\|124895136, gi... - gi\|84361585\|ref\|ZP_00986247.1\| COG1249: Pyruvate/2-oxoglutarate dehydrogenase complex, dihydrolipoam...	235.0	[0..10]	[497..2]
gi\|86570428, gi\|... - gi\|86747400\|ref\|YP_483896.1\| dihydrolipoamide dehydrogenase [Rhodopseudomonas palustris HaA2], gi\|86...	234.0	[0..10]	[496..1]
gi\|22652790 - gi\|22652790\|gb\|AAN03817.1\|AF497852_3 dihydrolipoamide dehydrogenase [Methylobacterium extorquens] gi\|240008178, gi... - gi\|240138209\|ref\|YP_002962681.1\| dihydrolipoamide dehydrogenase, FAD/NAD(P)-binding, component of th... gi\|218522208, gi... - gi\|218529905\|ref\|YP_002420721.1\| dihydrolipoamide dehydrogenase [Methylobacterium chloromethanicum C...	234.0	[0..13]	[497..3]
gi\|77654730, gi\|... - gi\|91975030\|ref\|YP_567689.1\| dihydrolipoamide dehydrogenase [Rhodopseudomonas palustris BisB5], gi\|9...	234.0	[0..10]	[496..1]

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Predicted Domain #1

Region A:
Residues: [1-498]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MTTPKKEIDR TIYDLLGIGI GPFNLGLAAL CEPINDLSCL FLDAKTEFDW HPGMLINSSR  60
   61 LQTPFMSDLV TMADPTSRFS YLNFAKQTSR LYSFYIRENF FLPRHEYNQY CQWVSKQLSN 120
  121 LNFGVKVTQV NYNAGEGIYA VTAIDRRSGK PLTYLCRKLV LGTGTTPYLP DNCPIQDPRV 180
  181 MHSASYMQQK TYLQSQSAIT VIGSGQSAAE IFYDLLQDID IYGYQLNWMT RSPRFYPLEY 240
  241 TKLTLEMTSP DYVDYFHELS SEKRHRLITE QKSLYKGINA ELINDIYDLL YQKRLISNIQ 300
  301 CQLLTNVALT AIDTSGDKLK LQFKHLEQDY ALDQLTSAVV LGTGYQYHLP DFIQGIKSQI 360
  361 EFDDHGQLAI QRDYGIDVRG DIFIQNAGLH THGISSPDLG MGCYRNATIL QAVLGYAPYP 420
  421 IETRIAFQTF APCNIADAKR QPLESNTHSA VTPSKTRQGL NPSAKSVQQP SIEPQTALRI 480
  481 APTGGNVSAL MAPNKEAQ

[Run NCBI BLAST on this sequence.]

Detection Method:	PSI-BLAST
Confidence:	59.69897
Match:	1jehA
Description:	Dihydrolipoamide dehydrogenase
Matching Structure (courtesy of the PDB):

Predicted functions:

Term	Confidence	Notes
oxidoreductase activity, acting on sulfur group of donors, NAD or NADP as acceptor	2.70464660743861	bayes_pls_golite062009
oxidoreductase activity, acting on sulfur group of donors	2.52390386317571	bayes_pls_golite062009
dihydrolipoyl dehydrogenase activity	2.36100558981647	bayes_pls_golite062009
catalytic activity	2.35839632763616	bayes_pls_golite062009
oxidoreductase activity, acting on NADH or NADPH	2.30491166641926	bayes_pls_golite062009
binding	1.30824465622666	bayes_pls_golite062009
antioxidant activity	1.15612787867475	bayes_pls_golite062009
disulfide oxidoreductase activity	0.905076028978344	bayes_pls_golite062009
oxidoreductase activity, oxidizing metal ions	0.87904288478579	bayes_pls_golite062009
oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor	0.37795133659497	bayes_pls_golite062009
NADPH-adrenodoxin reductase activity	0.364308821777151	bayes_pls_golite062009
pyruvate dehydrogenase activity	0.12794918372939	bayes_pls_golite062009
protein binding	0.065994258320842	bayes_pls_golite062009

TMHMM	2.0c	PSIPRED	v2.61
SignalP	3.0	COILS	1999
DISOPRED	v0.1	NCBI nr	06/2007
PSI-BLAST	2.2.18	FFAS	ffas03
PDB	06/2007	Pfam	22
HMMER	2.3.2

View Structure Prediction Details

Top Sequence Alignment Hits

Predicted functions: