YRC Public Data Repository - Protein Structure Prediction

Protein:	gi\|24374418, gi\|...
Organism:	Shewanella oneidensis MR-1
Length:	869 amino acids
Reference:	Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16

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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for gi|24374418, gi|....

Description	E-value	Query Range	Subject Range
gi\|71909161, gi\|... - gi\|71909161\|ref\|YP_286748.1\| PAS/PAC sensor hybrid histidine kinase [Dechloromonas aromatica RCB], g...	280.0	[0..20]	[864..16]
gi\|186682207, gi... - gi\|23127221\|ref\|ZP_00109095.1\| COG0642: Signal transduction histidine kinase [Nostoc punctiforme PCC...	276.0	[0..11]	[864..9]
gi\|77701293, gi\|... - gi\|77738825\|ref\|ZP_00807318.1\| PAS [Rhodopseudomonas palustris BisA53], gi\|77701293\|gb\|EAO92430.1\| P...	274.0	[0..27]	[864..27]
gi\|78687521, gi\|... - gi\|78687521\|ref\|ZP_00852267.1\| PAS [Shewanella sp. ANA-3], gi\|78504733\|gb\|EAP18280.1\| PAS [Shewanell...	268.0	[0..1]	[867..1]
gi\|78509358, gi\|... - gi\|78691251\|ref\|ZP_00855876.1\| PAS [Shewanella sp. MR-7], gi\|78509358\|gb\|EAP22755.1\| PAS [Shewanella...	266.0	[0..1]	[867..1]
gi\|82495952, gi\|... - gi\|82495952\|ref\|ZP_00881524.1\| PAS [Shewanella sp. MR-4], gi\|82405993\|gb\|EAP46661.1\| PAS [Shewanella...	266.0	[0..1]	[867..1]
gi\|108805455, gi... - gi\|108805455\|ref\|YP_645392.1\| multi-sensor hybrid histidine kinase [Rubrobacter xylanophilus DSM 994...	260.0	[0..38]	[863..42]

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Predicted Domain #1

Region A:
Residues: [1-369]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MDKRPNIEAQ APLTQWQKSL PFKLTLIQLL IASILIFSTA WVILNIQTQQ INEQQTLLNQ  60
   61 NHGQIIIAKL QEMTSQVENQ VNAISQIAML YRHEPEQLSK SIPELLSIES QKDIISGGGI 120
  121 WPEPGAFNRQ KFRDSLFWSH NIHGELVAID SYNDDNFPSY HTEEWYRPTR FFPAGKVFWS 180
  181 KSYVDLTTHE PMVTASSAMW MEHQFIGAAT TDISLEKLNQ LLRNAMLNVS GYVMALDHQN 240
  241 QILAFPNRDN TLQSHSDTTH NLISFDAFAQ TEQALTPIAS ALHLADRTFI EQAIAERVFT 300
  301 QEQMENLTRL SKDSERDMLS AIVNDNAKNH FSTPKRIALV SLAMDPILKG PSLVSVFLMP 360
  361 HTYWKILVV

[Run NCBI BLAST on this sequence.]

Detection Method:	FFAS03
Confidence:	3.89
Match:	2p7jA
Description:	No description for 2p7jA was found.

Predicted functions:

Term	Confidence	Notes
two-component sensor activity	2.88093868237858	bayes_pls_golite062009
protein histidine kinase activity	2.86151216540335	bayes_pls_golite062009
phosphotransferase activity, nitrogenous group as acceptor	2.80671328721504	bayes_pls_golite062009
two-component response regulator activity	1.62873572477094	bayes_pls_golite062009
signal transducer activity	1.10204821596482	bayes_pls_golite062009
molecular transducer activity	1.10204821596482	bayes_pls_golite062009
binding	0.704248066961418	bayes_pls_golite062009
protein kinase activity	0.510808146850279	bayes_pls_golite062009
phosphotransferase activity, alcohol group as acceptor	0.399812011068743	bayes_pls_golite062009
kinase activity	0.223004824807113	bayes_pls_golite062009
transferase activity, transferring phosphorus-containing groups	0.0995264574132551	bayes_pls_golite062009

Predicted Domain #2

Region A:
Residues: [370-453]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 TPVAPLEDTA KKLIEKVGLS LVLIQMFGLI LLFILQHKLI MAPIMEMVKA LKRNDSASIE  60
   61 LKAKERHDEV GLLAKTFLSR TQQL

[Run NCBI BLAST on this sequence.]

Detection Method:	FFAS03
Confidence:	2.15
Match:	2f95B
Description:	M intermediate structure of sensory rhodopsin II/transducer complex in combination with the ground state structure
Matching Structure (courtesy of the PDB):

Predicted Domain #3

Region A:
Residues: [454-623]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 EIAMSSLDAS NLALEQQLLS QQHFQQELNR HKEQLRSLLD YSSTIIYIKD LNGRYTLVNN  60
   61 KYCEVLGIER RKIIGAMDFE LFQPPLAELY QQNDQRANNS HDALHFEEPI PTPRGEIIYH 120
  121 MTKFDIRDDE DNSIGVGAIG FNVDLKKRQE KEQEKLLQYQ LNQLKDQQHK

[Run NCBI BLAST on this sequence.]

Detection Method:	FFAS03
Confidence:	4.25
Match:	1v9yA
Description:	Crystal Structure of the heme PAS sensor domain of Ec DOS (ferric form)
Matching Structure (courtesy of the PDB):

Predicted functions:

Term	Confidence	Notes
binding	1.67984576110273	bayes_pls_golite062009
two-component response regulator activity	1.41577088905201	bayes_pls_golite062009
transcription regulator activity	0.931375605669218	bayes_pls_golite062009
protein binding	0.888256242702267	bayes_pls_golite062009
DNA binding	0.533187513797767	bayes_pls_golite062009
two-component sensor activity	0.466388018187262	bayes_pls_golite062009
protein histidine kinase activity	0.452475261443277	bayes_pls_golite062009
phosphotransferase activity, nitrogenous group as acceptor	0.409938237891918	bayes_pls_golite062009
nucleic acid binding	0.387046112137798	bayes_pls_golite062009
signal transducer activity	0.341738261779128	bayes_pls_golite062009
molecular transducer activity	0.341738261779128	bayes_pls_golite062009
transcription factor activity	0.15709070306709	bayes_pls_golite062009

Predicted Domain #4

Region A:
Residues: [624-869]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 TQLAQQEIAQ LRAQLTDAND EINLQTQLNR NKQQSQKLMQ HFLSDVMNQM MQEQDRLLAQ  60
   61 VCQHKDADQH THVVQLMSQQ AARLRQISQL FTVQQSEIRP LHLAQFFQHL LSLLQPQLLK 120
  121 AQVKVSLSCD EQLVIDGDAW QYLQFFYRLL NNTLQHAFKD HHQHRELLLQ LKKQGHELQL 180
  181 LVKDNGVGLS ASKLEQLRHE MQQKQCTGTL SSLNLWIKDE LKGELNIKSE LNQGTRIECH 240
  241 WPLSKA

[Run NCBI BLAST on this sequence.]

Detection Method:	PSI-BLAST
Confidence:	44.0
Match:	2c2aA
Description:	Structure of the entire cytoplasmic portion of a sensor histidine kinase protein
Matching Structure (courtesy of the PDB):

TMHMM	2.0c	PSIPRED	v2.61
SignalP	3.0	COILS	1999
DISOPRED	v0.1	NCBI nr	06/2007
PSI-BLAST	2.2.18	FFAS	ffas03
PDB	06/2007	Pfam	22
HMMER	2.3.2

View Structure Prediction Details

Top Sequence Alignment Hits

Predicted functions:

Predicted functions: