YRC Public Data Repository - Protein Structure Prediction

Protein:	gi\|24374325, gi\|...
Organism:	Shewanella oneidensis MR-1
Length:	470 amino acids
Reference:	Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16

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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for gi|24374325, gi|....

Description	E-value	Query Range	Subject Range
gi\|151939187, gi... - gi\|75856580\|ref\|ZP_00764206.1\| COG2925: Exonuclease I [Vibrio sp. Ex25], gi\|254228381\|ref\|ZP_0492180...	551.0	[0..1]	[470..1]
gi\|46913312, gi\|... - gi\|54308882\|ref\|YP_129902.1\| exonuclease I [Photobacterium profundum SS9], gi\|46913312\|emb\|CAG20100....	550.0	[0..1]	[466..1]
gi\|90323813, gi\|... - gi\|90415078\|ref\|ZP_01223036.1\| putative exonuclease I [Photobacterium profundum 3TCK], gi\|90323813\|g...	550.0	[0..1]	[466..1]
gi\|27362277, gi\|... - gi\|27366077\|ref\|NP_761605.1\| exonuclease I [Vibrio vulnificus CMCP6], gi\|27362277\|gb\|AAO11132.1\|AE01...	550.0	[0..1]	[470..1]
gi\|225354920, gi... - gi\|75819022\|ref\|ZP_00749126.1\| COG2925: Exonuclease I [Vibrio cholerae V51], gi\|254226438\|ref\|ZP_049...	549.0	[0..1]	[470..1]
gi\|75823339, gi\|... - gi\|75823339\|ref\|ZP_00752847.1\| COG2925: Exonuclease I [Vibrio cholerae RC385], gi\|254224153\|ref\|ZP_0... tr\|D7H875\|D7H875... - Exodeoxyribonuclease I OS=Vibrio cholerae RC385 GN=VCRC385_01948 PE=4 SV=1	548.0	[0..1]	[470..1]
gi\|37198401, gi\|... - gi\|37679656\|ref\|NP_934265.1\| exonuclease I [Vibrio vulnificus YJ016], gi\|37198401\|dbj\|BAC94236.1\| ex...	548.0	[0..1]	[470..1]
gi\|91223947, gi\|... - gi\|91223947\|ref\|ZP_01259211.1\| exodeoxyribonuclease I [Vibrio alginolyticus 12G01], gi\|91191439\|gb\|E...	547.0	[0..1]	[470..1]
gi\|11263253 - pir\|\|B82227 exodeoxyribonuclease I VC1234 [imported] - Vibrio cholerae (strain N16961 serogroup O1) gi\|121591211, gi... - gi\|121591211\|ref\|ZP_01678513.1\| exodeoxyribonuclease I [Vibrio cholerae 2740-80], gi\|121546936\|gb\|EA... gi\|121728822, gi... - gi\|121728822\|ref\|ZP_01681834.1\| exodeoxyribonuclease I [Vibrio cholerae V52], gi\|121628910\|gb\|EAX613... gi\|124118847, gi... - gi\|153222510\|ref\|ZP_01953232.1\| exodeoxyribonuclease I [Vibrio cholerae MAK 757], gi\|124118847\|gb\|EA... gi\|153819174, gi... - gi\|153819174\|ref\|ZP_01971841.1\| exodeoxyribonuclease I [Vibrio cholerae NCTC 8457], gi\|126510260\|gb\|... gi\|15641247, gi\|... - gi\|9655715\|gb\|AAF94393.1\| exodeoxyribonuclease I [Vibrio cholerae O1 biovar El Tor str. N16961], gi\|... gi\|254848359, gi... - gi\|75829647\|ref\|ZP_00758943.1\| COG2925: Exonuclease I [Vibrio cholerae MO10], gi\|254848359\|ref\|ZP_05... gi\|153823017, gi... - gi\|153823017\|ref\|ZP_01975684.1\| exodeoxyribonuclease I [Vibrio cholerae B33], gi\|126519445\|gb\|EAZ766... gi\|227013151, gi... - gi\|75826629\|ref\|ZP_00756064.1\| COG2925: Exonuclease I [Vibrio cholerae O395], gi\|227117701\|ref\|YP_00... gi\|227009294, gi... - gi\|227081406\|ref\|YP_002809957.1\| exodeoxyribonuclease I [Vibrio cholerae M66-2], gi\|227009294\|gb\|ACP...	547.0	[0..1]	[470..1]
gi\|28806289 - gi\|28806289\|dbj\|BAC59564.1\| exodeoxyribonuclease I [Vibrio parahaemolyticus RIMD 2210633] gi\|153836551, gi... - gi\|153836551\|ref\|ZP_01989218.1\| exodeoxyribonuclease I [Vibrio parahaemolyticus AQ3810], gi\|14975014... gi\|28806289, gi\|... - gi\|28898075\|ref\|NP_797680.1\| exonuclease I [Vibrio parahaemolyticus RIMD 2210633], gi\|28806289\|dbj\|B...	545.0	[0..1]	[470..1]

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Predicted Domain #1

Region A:
Residues: [1-470]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MYTASQPSIF WHDYETFGAN PAKDRPAQFA GIRTDLDLNI ISEPETFYCK QSTDYLPSPE  60
   61 AILITGITPQ LANLKGLPET EFMGRIHTLF SQANTCVAGY NSLRFDDEVT RYGFYRNFID 120
  121 PYAREWQNGN TRWDIIDLVR ACYAFRPDGI HWPLKEDGSP SFKLEHLTQA NGLSHEKAHD 180
  181 AMSDVYATIA MAKLIKEKQP KLYQYYFELR RKQAVSAQID VLNMQPLAHV SSKISAMHGC 240
  241 TTLIAPVAHH PSNKNAIICV NLAMDLSPLF ELDVEQIKTR MYTPRAELAD DELPIPVKQV 300
  301 HLNKCPFITS AKILDDAQAE RLSIDKAFAR GQYKRLKAHP ELREKLAQLF EHDGEATTTD 360
  361 PDLMLYSGGF FSPADKAKME IIRHTLPQNL AALDLQFDDG RIPEMLFRYR ARNYPELLDD 420
  421 QESHRWRTFC QQRLADQDYL LKLENLLQDT EGDEHKQKLL AALCHYLRGL

[Run NCBI BLAST on this sequence.]

Detection Method:	PSI-BLAST
Confidence:	154.0
Match:	1fxxA
Description:	Exonuclease I
Matching Structure (courtesy of the PDB):

Predicted functions:

Term	Confidence	Notes
hydrolase activity	2.30893115816458	bayes_pls_golite062009
ribonuclease activity	2.27368058469313	bayes_pls_golite062009
hydrolase activity, acting on ester bonds	2.26022264830742	bayes_pls_golite062009
nuclease activity	1.81796593394339	bayes_pls_golite062009
endonuclease activity	1.79009816048707	bayes_pls_golite062009
exonuclease activity	1.64964907710028	bayes_pls_golite062009
catalytic activity	1.62277843225829	bayes_pls_golite062009
endoribonuclease activity	1.5391920929568	bayes_pls_golite062009
ribonuclease H activity	1.03274213246433	bayes_pls_golite062009
exodeoxyribonuclease I activity	0.70661333047946	bayes_pls_golite062009
deoxyribonuclease activity	0.63299586096139	bayes_pls_golite062009
exonuclease activity, active with either ribo- or deoxyribonucleic acids and producing 5'-phosphomonoesters	0.62821439153618	bayes_pls_golite062009
exoribonuclease activity	0.1529022053594	bayes_pls_golite062009
exoribonuclease activity, producing 5'-phosphomonoesters	0.0105328395026505	bayes_pls_golite062009

TMHMM	2.0c	PSIPRED	v2.61
SignalP	3.0	COILS	1999
DISOPRED	v0.1	NCBI nr	06/2007
PSI-BLAST	2.2.18	FFAS	ffas03
PDB	06/2007	Pfam	22
HMMER	2.3.2

View Structure Prediction Details

Top Sequence Alignment Hits

Predicted functions: