YRC Public Data Repository - Protein Structure Prediction

Protein:	gi\|24374179, gi\|...
Organism:	Shewanella oneidensis MR-1
Length:	344 amino acids
Reference:	Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16

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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for gi|24374179, gi|....

Description	E-value	Query Range	Subject Range
gi\|20808583, gi\|... - gi\|20808583\|ref\|NP_623754.1\| glutamate dehydrogenase/leucine dehydrogenase [Thermoanaerobacter tengc... gi\|20808583 - gi\|20808583\|ref\|NP_623754.1\| Glutamate dehydrogenase/leucine dehydrogenase [Thermoanaerobacter tengc...	288.0	[0..1]	[344..1]
DHLE_BACSU - Leucine dehydrogenase OS=Bacillus subtilis (strain 168) GN=yqiT PE=3 SV=1 gi\|221314652 - gi\|221314652\|ref\|ZP_03596457.1\| leucine dehydrogenase [Bacillus subtilis subsp. subtilis str. NCIB 3... DHLE_BACSU - Leucine dehydrogenase OS=Bacillus subtilis GN=yqiT PE=3 SV=1 gi\|221319575 - gi\|221319575\|ref\|ZP_03600869.1\| leucine dehydrogenase [Bacillus subtilis subsp. subtilis str. JH642] gi\|221323851 - gi\|221323851\|ref\|ZP_03605145.1\| leucine dehydrogenase [Bacillus subtilis subsp. subtilis str. SMY]	281.0	[0..1]	[343..1]
gi\|42543921 - gi\|42543921\|dbj\|BAD11020.1\| leucine dehydrogenase [Bacillus sphaericus]	281.0	[0..1]	[342..1]
gi\|143146, gi\|80215 - pir\|\|A31950 leucine dehydrogenase (EC 1.4.1.9) - Bacillus stearothermophilus, gi\|143146\|gb\|AAA22570...	280.0	[0..1]	[343..1]
DHLE_THEIN - Leucine dehydrogenase OS=Thermoactinomyces intermedius GN=ldh PE=1 SV=1	280.0	[0..1]	[343..1]
gi\|56380758, gi\|... - gi\|56420916\|ref\|YP_148234.1\| leucine dehydrogenase [Geobacillus kaustophilus HTA426], gi\|56380758\|db... gi\|221088864, gi... - gi\|221088864\|ref\|ZP_03558390.1\| Glu/Leu/Phe/Val dehydrogenase [Geobacillus sp. Y412MC61], gi\|2207072... gi\|47076832 - gi\|47076832\|dbj\|BAD18372.1\| leucine dehydrogenase [Geobacillus kaustophilus]	278.0	[0..1]	[343..1]
gi\|22777553, gi\|... - gi\|23099324\|ref\|NP_692790.1\| leucine dehydrogenase [Oceanobacillus iheyensis HTE831], gi\|22777553\|db...	277.0	[0..1]	[343..1]

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Predicted Domain #1

Region A:
Residues: [1-344]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MAVFNHVSFD EHEQVVFCHD KESGLKAIIA IHNTNLGPAV GGCRMWNYQS DDEALTDVLR  60
   61 LSRGMTYKNA LAGLTMGGGK SVIIADPKRP DREALFRAFG RFINSLGGRY YSAEDVGTTT 120
  121 ADIMIAHQET PYMAGLEGKS GDPSPFTALG TYLGIKAAVK HKLDLDSLKG LKIAVQGVGH 180
  181 VGYYLCKHLH EEGAQLIVTD IHQASLDKVA TDFGATVVAP QDIYAQDVDV YAPCALGATL 240
  241 NDVTLPLLKA KIVAGCANNQ LAEVRHGEQL KEMGILYAPD YVINAGGIIN VSFEKDYDAA 300
  301 KSEAKVREIY NTLLKIFAKA DAENRTTGAV ADEMARAIYQ AAKA

[Run NCBI BLAST on this sequence.]

Detection Method:	PSI-BLAST
Confidence:	69.0
Match:	1lehA
Description:	Leucine dehydrogenase
Matching Structure (courtesy of the PDB):

Predicted functions:

Term	Confidence	Notes
catalytic activity	2.43483529599631	bayes_pls_golite062009
oxidoreductase activity	2.40835256378153	bayes_pls_golite062009
oxidoreductase activity, acting on CH-OH group of donors	1.78381957137814	bayes_pls_golite062009
malate dehydrogenase activity	1.29890335901924	bayes_pls_golite062009
malic enzyme activity	0.82576094727244	bayes_pls_golite062009
oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor	0.73772847519488	bayes_pls_golite062009
ketol-acid reductoisomerase activity	0.0479950038396302	bayes_pls_golite062009

TMHMM	2.0c	PSIPRED	v2.61
SignalP	3.0	COILS	1999
DISOPRED	v0.1	NCBI nr	06/2007
PSI-BLAST	2.2.18	FFAS	ffas03
PDB	06/2007	Pfam	22
HMMER	2.3.2

View Structure Prediction Details

Top Sequence Alignment Hits

Predicted functions: