YRC Public Data Repository - Protein Structure Prediction

Protein:	gi\|24374171, gi\|...
Organism:	Shewanella oneidensis MR-1
Length:	741 amino acids
Reference:	Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16

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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for gi|24374171, gi|....

Description	E-value	Query Range	Subject Range
gi\|113530366, gi... - gi\|116695867\|ref\|YP_841443.1\| isocitrate dehydrogenase [NADP] [Ralstonia eutropha H16], gi\|113530366...	1460.0	[0..1]	[740..1]
gi\|37926514, gi\|... - gi\|67155876\|ref\|ZP_00417503.1\| Isocitrate dehydrogenase NADP-dependent, monomeric type [Azotobacter ... gi\|67155876, gi\|... - gi\|67155876\|ref\|ZP_00417503.1\| Isocitrate dehydrogenase NADP-dependent, monomeric type [Azotobacter ...	1452.0	[0..4]	[740..2]
IDH_AZOVI - Isocitrate dehydrogenase [NADP] OS=Azotobacter vinelandii GN=icd PE=1 SV=5	1449.0	[0..4]	[740..2]
gi\|34499119, gi\|... - gi\|34499119\|ref\|NP_903334.1\| isocitrate dehydrogenase (NADP) [Chromobacterium violaceum ATCC 12472],...	1449.0	[0..1]	[741..1]
gi\|73538031, gi\|... - gi\|73538031\|ref\|YP_298398.1\| isocitrate dehydrogenase NADP-dependent, monomeric type [Ralstonia eutr...	1444.0	[0..1]	[741..1]
gi\|21615534 - gi\|21615534\|emb\|CAD32551.1\| isocitrate dehydrogenase isozyme 2 [Cupriavidus necator] gi\|21615534 - gi\|21615534\|emb\|CAD32551.1\| isocitrate dehydrogenase isozyme 2 [Cupriavidus necator]	1444.0	[0..1]	[740..1]
gi\|93356513, gi\|... - gi\|94312661\|ref\|YP_585870.1\| isocitrate dehydrogenase, NADP-dependent [Ralstonia metallidurans CH34]...	1435.0	[0..1]	[741..1]
gi\|91229060, gi\|... - gi\|91229060\|ref\|ZP_01262886.1\| isocitrate dehydrogenase [Vibrio alginolyticus 12G01], gi\|91187453\|gb...	1434.0	[0..1]	[740..1]
gi\|67547113, gi\|... - gi\|67547113\|ref\|ZP_00425020.1\| Isocitrate dehydrogenase NADP-dependent, monomeric type [Burkholderia...	1433.0	[0..1]	[741..86]
gi\|194562601, gi... - gi\|84362672\|ref\|ZP_00987288.1\| COG2838: Monomeric isocitrate dehydrogenase [Burkholderia dolosa AUO1...	1431.0	[0..1]	[741..1]

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Predicted Domain #1

Region A:
Residues: [1-741]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MKDNSPTIIY TETDEAPALA TLSLLPIIKT FTNAADVAVE TRDISLSGRV IANFPEKLTD  60
   61 AQKIGDHLAE LGDLANQPEA NIIKLPNISA SIPQLKACIL ELQQKGYDIP NYPDEPKTDE 120
  121 EKSIKARYDK IKGSAVNPVL REGNSDRRAP LSVKNFAKKN PHSMGKWVKD SKSHVAHMSE 180
  181 GDFYGSELSV TLSNADTVNI VLAQKDGQEV VLKSGLKLLA GEIIDASVMS KKALVSFFER 240
  241 EIANAKAENV LLSLHLKATM MKVSDPIMFG HAVKVFFKPV FDKHAALFAE LGVDVNNGFG 300
  301 DVYAKIASLP TDVRSQIEAD IAAVYAEGPA LAMVDSDKGI TNLHVPSDII IDASMPAAIR 360
  361 SSGQMWGPDG KLHDTKALIP DRCYAGVYQE TIAFCKEHGA FDPSTMGSVP NVGLMAQKAE 420
  421 EYGSHDKTFE IPADGVVNVI DASGKVLMSH NVEAGDIWRM CQVKDAPIRD WVKLAVRRAR 480
  481 LSNTPAVFWL DANRAHDAQL IVKVKQYLPE HDTSGLDISI MSPEEATRFS LARIKEGKDT 540
  541 ISVTGNVLRD YLTDLFPILE LGTSAKMLSI VPLMNGGGLF ETGAGGSAPK HVQQVEKEGH 600
  601 LRWDSLGEFL ALAASLEHLS QTVGNPKAQV LADTLDQAIG QFLDSNKSPS RRVGELDNRG 660
  661 SHFYLAMYWA QALAVQTKDE QLQAHFIPLA HALSANEQVI VAELNNAQGA PVDLGGYYRL 720
  721 DAVKAEKAMR PSETLNKLLI A

[Run NCBI BLAST on this sequence.]

Detection Method:	PSI-BLAST
Confidence:	1000.0
Match:	1itwA
Description:	Monomeric isocitrate dehydrogenase
Matching Structure (courtesy of the PDB):

Predicted functions:

Term	Confidence	Notes
isocitrate dehydrogenase activity	3.62126393776639	bayes_pls_golite062009
catalytic activity	3.08295953338337	bayes_pls_golite062009
oxidoreductase activity	2.6468198750213	bayes_pls_golite062009
isocitrate dehydrogenase (NADP+) activity	2.29271552032599	bayes_pls_golite062009
isocitrate dehydrogenase (NAD+) activity	2.10234418832459	bayes_pls_golite062009
oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor	1.47802406005381	bayes_pls_golite062009
oxidoreductase activity, acting on CH-OH group of donors	1.44962743981001	bayes_pls_golite062009

TMHMM	2.0c	PSIPRED	v2.61
SignalP	3.0	COILS	1999
DISOPRED	v0.1	NCBI nr	06/2007
PSI-BLAST	2.2.18	FFAS	ffas03
PDB	06/2007	Pfam	22
HMMER	2.3.2

View Structure Prediction Details

Top Sequence Alignment Hits

Predicted functions: