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View Structure Prediction Details

Protein: gi|24374087, gi|...
Organism: Shewanella oneidensis MR-1
Length: 1019 amino acids
Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16



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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for gi|24374087, gi|....

Description E-value Query
Range
Subject
Range
gi|53687593 - gi|53687593|ref|ZP_00108373.2| COG0642: Signal transduction histidine kinase [Nostoc punctiforme PCC...
406.0 [0..154] [1000..24]
gi|17232370, gi|... - gi|17232370|ref|NP_488918.1| two-component hybrid sensor and regulator [Nostoc sp. PCC 7120], gi|171...
gi|25533334 - pir||AF2415 two-component hybrid sensor and regulator alr4878 [imported] - Nostoc sp. (strain PCC 71...
400.0 [0..147] [992..35]
gi|53764618, gi|... - gi|75908367|ref|YP_322663.1| Cache sensor hybrid histidine kinase [Anabaena variabilis ATCC 29413], ...
400.0 [0..147] [992..31]
gi|150017029, gi... - gi|82745764|ref|ZP_00908274.1| Response regulator receiver:ATP-binding region, ATPase-like:Histidine...
372.0 [0..136] [1015..5]
gi|88819918, gi|... - gi|88858301|ref|ZP_01132943.1| hypothetical protein PTD2_12964 [Pseudoalteromonas tunicata D2], gi|8...
363.0 [0..178] [1015..17]
gi|7470838 - pir||S77225 sensory transduction histidine kinase sll1353 - Synechocystis sp. (strain PCC 6803)
gi|16330151, gi|... - gi|1652639|dbj|BAA17559.1| sensory transduction histidine kinase [Synechocystis sp. PCC 6803], gi|16...
362.0 [0..17] [778..12]
gi|78366316, gi|... - gi|78366316|ref|ZP_00836597.1| PAS [Shewanella sp. PV-4], gi|78361632|gb|EAP03455.1| PAS [Shewanella...
355.0 [0..186] [1018..651]
gi|71676531, gi|... - gi|71676531|ref|ZP_00674272.1| Guanylate cyclase:Response regulator receiver:ATP-binding region, ATP...
355.0 [0..139] [1018..12]
gi|91201482 - gi|91201482|emb|CAJ74542.1| similar to hybrid sensor [Candidatus Kuenenia stuttgartiensis]
354.0 [0..420] [1019..174]
gi|68516760, gi|... - gi|68545731|ref|ZP_00585281.1| PAS [Shewanella amazonensis SB2B], gi|68516760|gb|EAN40471.1| PAS [Sh...
353.0 [0..194] [1012..605]

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Predicted Domain #1
Region A:
Residues: [1-158]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MLAMIKTYNK SIKRHRLLFL LYCITVGLLA NLSVVAIPIA VPLNVGNVAI LVILARLGPL  60
   61 WALVCFAFVT YPLPSDIAII LTIVQVILFG FYINQKNSSI IKISIAYVAI VFIANKFLLP 120
  121 EAITDNQISL LTFTSLSTAL FIWTIKATNL LLSLYVNN

[Run NCBI BLAST on this sequence.]

Detection Method: deduced

Shown below is our most confident de novo (Rosetta) prediction for this domain.
Click here to view all matches.

Found no confident structure predictions for this domain.

Predicted Domain #2
Region A:
Residues: [159-419]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 EQLRKQSLQH QLSYRVGLYT AIPATLLITL GLNGVTNLHL VKQMAYYQNE VNELNKNIEE  60
   61 KLKNYSNKIE TIAKLTDIEV TKRILMQLVS QSPEFISALI TDTNGTVNKF YKKDINDDRI 120
  121 AKASVADRAY FYEVKKTMST YISDTFTGRS LGEDQLFAVS TPIIDNNQFN GVLQLAIKLD 180
  181 SLLEVFNLPN DSISHRILID NSGKKVWGNN ISGDVGSIWI RPKHSEPMQK AFLEKSLFNP 240
  241 LEPIIFSQDA HHLIISNQVG A

[Run NCBI BLAST on this sequence.]

Detection Method: FFAS03
Confidence: 4.02
Match: 2p7jA
Description: No description for 2p7jA was found.

Predicted functions:

Term Confidence Notes
two-component sensor activity 2.88093868237858 bayes_pls_golite062009
protein histidine kinase activity 2.86151216540335 bayes_pls_golite062009
phosphotransferase activity, nitrogenous group as acceptor 2.80671328721504 bayes_pls_golite062009
protein kinase activity 1.74105675066805 bayes_pls_golite062009
two-component response regulator activity 1.62873572477094 bayes_pls_golite062009
phosphotransferase activity, alcohol group as acceptor 1.58981311381645 bayes_pls_golite062009
kinase activity 1.5133458700147 bayes_pls_golite062009
transferase activity, transferring phosphorus-containing groups 1.31628115739307 bayes_pls_golite062009
signal transducer activity 1.10204821596482 bayes_pls_golite062009
molecular transducer activity 1.10204821596482 bayes_pls_golite062009
catalytic activity 0.970922685016416 bayes_pls_golite062009
transferase activity 0.839270468560673 bayes_pls_golite062009
binding 0.704248066961418 bayes_pls_golite062009

Predicted Domain #3
Region A:
Residues: [420-533]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 TDWKLYFFID TDELTLDFSI YYLLSLLLIT LILEISVQFS KRFVKHYTQA LELLVDYTQQ  60
   61 WDGKSTTKKN LNFTQSALEI DTLAHSFVNM QRRVAGAHHA IISTMNEVKL LNEA

[Run NCBI BLAST on this sequence.]

Detection Method: FFAS03
Confidence: 3.13
Match: 2f95B
Description: M intermediate structure of sensory rhodopsin II/transducer complex in combination with the ground state structure
Matching Structure (courtesy of the PDB):

Predicted Domain #4
Region A:
Residues: [534-789]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 LEERVEKRTK ELEQERDKAN QLAAVKARFL ANMSHEIRTP ITIIKGFTEQ ILPNTQGEVH  60
   61 NALCKIEQNT LHLQNVINDI LDAAKIDEGK MTIAEQTVAI IPLLNSLSDS MKFLARTKNL 120
  121 TTELNIDIAD IEHIITDPFR LKQILLNFIS NAVKFTPKGT VKLVANITNA DELCIAVIDK 180
  181 GIGISDQQAS TLFEAFTQAD SSTSRDFGGT GLGLFISKQL ADAMFIKLHM QSELGVGSCF 240
  241 SVTLPESKII KNLTEF

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 47.69897
Match: 2c2aA
Description: Structure of the entire cytoplasmic portion of a sensor histidine kinase protein
Matching Structure (courtesy of the PDB):

Predicted Domain #5
Region A:
Residues: [790-1019]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 SKNEKKIEHT TPDWKNYHVL IVDDVEDIRE LIDIYLKDTE IAVDFAQNGQ QAIQLVEKSH  60
   61 YDLVILDQQM PIMDGFTAAK AIREFNKSIP LLLLSADILD TEPHQKSPFN KTIAKPFTKN 120
  121 QLIETIRLFI VDNSISTKKV NEEDEDELTI EYLHTLPNVL LLLEKLVKCE DRTHLEHELH 180
  181 KLKGTSACLG LIAISHCAAN LHNLLKERMI KLNELDDISL AVKNALKEKE 

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 30.69897
Match: 1kgsA
Description: PhoB; PhoB receiver domain
Matching Structure (courtesy of the PDB):

Predicted functions:

Term Confidence Notes
two-component response regulator activity 7.02872640261738 bayes_pls_golite062009
signal transducer activity 4.51666042720644 bayes_pls_golite062009
molecular transducer activity 4.51666042720644 bayes_pls_golite062009
transcription regulator activity 3.44888100104099 bayes_pls_golite062009
protein histidine kinase activity 2.35011582062573 bayes_pls_golite062009
two-component sensor activity 2.32303301074957 bayes_pls_golite062009
phosphotransferase activity, nitrogenous group as acceptor 2.28838869071567 bayes_pls_golite062009
binding 1.22427537074115 bayes_pls_golite062009
DNA binding 1.11037597107903 bayes_pls_golite062009
protein kinase activity 1.00737355751913 bayes_pls_golite062009
nucleic acid binding 0.93151849951839 bayes_pls_golite062009
phosphotransferase activity, alcohol group as acceptor 0.811771244977462 bayes_pls_golite062009
kinase activity 0.725824770559857 bayes_pls_golite062009
transcription factor activity 0.62886970109503 bayes_pls_golite062009
transferase activity, transferring phosphorus-containing groups 0.476057209677045 bayes_pls_golite062009

YRC Informatics Platform - Version 3.0
Created and Maintained by: Michael Riffle