YRC Public Data Repository - Protein Structure Prediction

Protein:	METE_SHEON
Organism:	Shewanella oneidensis MR-1
Length:	760 amino acids
Reference:	Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16

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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for METE_SHEON.

Description	E-value	Query Range	Subject Range
gi\|89104874 - gi\|89104874\|ref\|ZP_01177405.1\| COG0620: Methionine synthase II (cobalamin-independent) [Yersinia pes... gi\|167426239, gi... - gi\|167426239\|ref\|ZP_02317992.1\| 5-methyltetrahydropteroyltriglutamate--homocysteine S-methyltransfer... gi\|22124357, gi\|... - gi\|22124357\|ref\|NP_667780.1\| 5-methyltetrahydropteroyltriglutamate--homocysteine methyltransferase [... gi\|77633875, gi\|... - gi\|77633875\|ref\|ZP_00795989.1\| COG0620: Methionine synthase II (cobalamin-independent) [Yersinia pes... gi\|167401849, gi... - gi\|167401849\|ref\|ZP_02307337.1\| 5-methyltetrahydropteroyltriglutamate--homocysteine S-methyltransfer... gi\|166213623, gi... - gi\|166213623\|ref\|ZP_02239658.1\| 5-methyltetrahydropteroyltriglutamate--homocysteine S-methyltransfer...	997.0	[0..1]	[758..8]
gi\|149289461, gi... - gi\|153997155\|ref\|ZP_02022288.1\| 5-methyltetrahydropteroyltriglutamate-- homocystei ne methyltransfer... gi\|165921840, gi... - gi\|165926316\|ref\|ZP_02222148.1\| 5-methyltetrahydropteroyltriglutamate--homocysteine S-methyltransfer... gi\|165939105, gi... - gi\|165939105\|ref\|ZP_02227656.1\| 5-methyltetrahydropteroyltriglutamate--homocysteine S-methyltransfer... gi\|165989400, gi... - gi\|166011631\|ref\|ZP_02232529.1\| 5-methyltetrahydropteroyltriglutamate--homocysteine S-methyltransfer... gi\|166961025, gi... - gi\|167420896\|ref\|ZP_02312649.1\| 5-methyltetrahydropteroyltriglutamate--homocysteine S-methyltransfer... gi\|229695839, gi... - gi\|229839473\|ref\|ZP_04459632.1\| 5-methyltetrahydropteroyltriglutamate-homocysteine S-methyltransfera... gi\|229686816, gi... - gi\|229900036\|ref\|ZP_04515173.1\| 5-methyltetrahydropteroyltriglutamate-homocysteine S-methyltransfera... gi\|229706057, gi... - gi\|229837114\|ref\|ZP_04457279.1\| 5-methyltetrahydropteroyltriglutamate-homocysteine S-methyltransfera... METE_YERPE - 5-methyltetrahydropteroyltriglutamate--homocysteine methyltransferase OS=Yersinia pestis GN=metE PE=... METE_YERPN - 5-methyltetrahydropteroyltriglutamate--homocysteine methyltransferase OS=Yersinia pestis bv. Antiqua... METE_YERPA - 5-methyltetrahydropteroyltriglutamate--homocysteine methyltransferase OS=Yersinia pestis bv. Antiqua... gi\|45437880, gi\|... - gi\|45443013\|ref\|NP_994552.1\| 5-methyltetrahydropteroyltriglutamate--homocysteine methyltransferase [... gi\|218930790, gi... - gi\|218930790\|ref\|YP_002348665.1\| 5-methyltetrahydropteroyltriglutamate--homocysteine S-methyltransfe...	995.0	[0..1]	[758..3]
gi\|77973685 - gi\|77973685\|ref\|ZP_00829231.1\| COG0620: Methionine synthase II (cobalamin-independent) [Yersinia fre...	995.0	[0..1]	[758..3]
METE_ECOK1 - 5-methyltetrahydropteroyltriglutamate--homocysteine methyltransferase OS=Escherichia coli O1:K1 / AP...	995.0	[0..1]	[756..3]
gi\|77630686, gi\|... - gi\|77630686\|ref\|ZP_00793272.1\| COG0620: Methionine synthase II (cobalamin-independent) [Yersinia pse...	995.0	[0..1]	[758..8]
gi\|75256247, gi\|... - gi\|75256247\|ref\|ZP_00727925.1\| COG0620: Methionine synthase II (cobalamin-independent) [Escherichia ... gi\|193067979, gi... - gi\|75238279\|ref\|ZP_00722278.1\| COG0620: Methionine synthase II (cobalamin-independent) [Escherichia ... gi\|75209544, gi\|... - gi\|75209544\|ref\|ZP_00709765.1\| COG0620: Methionine synthase II (cobalamin-independent) [Escherichia ...	994.0	[0..1]	[756..3]
METE_ECO45 - 5-methyltetrahydropteroyltriglutamate--homocysteine methyltransferase OS=Escherichia coli O45:K1 (st... gi\|237702839, gi... - gi\|237702839\|ref\|ZP_04533320.1\| 5-methyltetrahydropteroyltriglutamate-homocysteine methyltransferase... METE_ECOUT - 5-methyltetrahydropteroyltriglutamate--homocysteine methyltransferase OS=Escherichia coli (strain UT...	994.0	[0..1]	[756..3]
METE_SHISS - 5-methyltetrahydropteroyltriglutamate--homocysteine methyltransferase OS=Shigella sonnei (strain Ss0... METE_ECOSE - 5-methyltetrahydropteroyltriglutamate--homocysteine methyltransferase OS=Escherichia coli (strain SE...	994.0	[0..1]	[756..3]
METE_ECO24 - 5-methyltetrahydropteroyltriglutamate--homocysteine methyltransferase OS=Escherichia coli O139:H28 (...	993.0	[0..1]	[756..3]
METE_ECOHS - 5-methyltetrahydropteroyltriglutamate--homocysteine methyltransferase OS=Escherichia coli O9:H4 (str...	993.0	[0..1]	[756..3]

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Predicted Domain #1

Region A:
Residues: [1-760]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MQLNSLGFPR IGRRRELKFA LEKYWRGEST QAELHEVARE LRRTHWQWQV AAGIEQVPVG  60
   61 DFAFYDQVLT LSATLNAIPD RHRGEGAIDL DTLFRVARGR APTGTDAPAS EMTKYFNTNY 120
  121 HYLVPELKQD QVFSIAYEQF FDEVAEAQAL GYKAKPVLLG PVSYLYLAKT VGQDFDKLSL 180
  181 LPNLLKAYAE ILARFAAQGV TWVQLEEPIL ALELTHEWQA AISESYQALK TAQVKILLTS 240
  241 YYGSISHHQA LVSALPVAGL HLDLVTAPEQ LALFANALRP DQILSVGVVN GRNVWAAEVD 300
  301 LIVERIGSVA RDLCSQDGSR LWIGTSCSLL HSPVDLEVET TLAPTLRQQL AFAKQKLLEL 360
  361 ANVRQLLQAP ESVAAKEIVN TCLARREAKA QAADAKVIAR VAALTPADYE RVSEFTERQA 420
  421 VQQRKYRLPL LPTTTIGSFP QTPAIRGLRS RWRKGELSDA QYTEQLQQVT RDTIDRQLKL 480
  481 GIDVLVHGEA ERNDMVEYFG EQLEGVGFTK NGWVQSYGSR CVKPPLIYGD VSRPKAMTVD 540
  541 WAVFAQSLTD KPVKGMLTGP VTILHWSFAR EDISRDTIAT QLALAIRDEV VDLQHAGIGI 600
  601 IQIDEPAFRE GLPLKQSEWQ AYLDWAVNAF KLSAAGVVDE TQIHTHMCYS EFNDTIAAIA 660
  661 AMDADVITIE TSRSRMELLN AFEDFEYPNE IGPGVYDIHS PNTPSVEAMV HLIEKAAQKV 720
  721 PVRQLWVNPD CGLKTRTWDE VEPALKNMVD ATRELRRRLG

[Run NCBI BLAST on this sequence.]

Detection Method:	PSI-BLAST
Confidence:	1000.0
Match:	1u1hA
Description:	A. thaliana cobalamine independent methionine synthase
Matching Structure (courtesy of the PDB):

Predicted functions:

Term	Confidence	Notes
5-methyltetrahydropteroyltriglutamate-homocysteine S-methyltransferase activity	6.40786073037099	bayes_pls_golite062009
5-methyltetrahydropteroyltri-L-glutamate-dependent methyltransferase activity	6.40786073037099	bayes_pls_golite062009
uroporphyrinogen decarboxylase activity	3.13638443707338	bayes_pls_golite062009
S-methyltransferase activity	3.0142199413027	bayes_pls_golite062009
catalytic activity	2.37862248560593	bayes_pls_golite062009
binding	1.590130518929	bayes_pls_golite062009
carbon-carbon lyase activity	1.54242506764415	bayes_pls_golite062009
carboxy-lyase activity	1.52150758949987	bayes_pls_golite062009
lyase activity	0.825209465219608	bayes_pls_golite062009
protein binding	0.21865699924356	bayes_pls_golite062009

TMHMM	2.0c	PSIPRED	v2.61
SignalP	3.0	COILS	1999
DISOPRED	v0.1	NCBI nr	06/2007
PSI-BLAST	2.2.18	FFAS	ffas03
PDB	06/2007	Pfam	22
HMMER	2.3.2

View Structure Prediction Details

Top Sequence Alignment Hits

Predicted functions: