YRC Public Data Repository - Protein Structure Prediction

Protein:	gi\|24345567, gi\|...
Organism:	Shewanella oneidensis MR-1
Length:	395 amino acids
Reference:	Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16

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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for gi|24345567, gi|....

Description	E-value	Query Range	Subject Range
gi\|114045672, gi... - gi\|78689151\|ref\|ZP_00853816.1\| General secretion pathway L [Shewanella sp. MR-7], gi\|78511551\|gb\|EAP...	407.0	[0..1]	[395..1]
gi\|82495889, gi\|... - gi\|82495889\|ref\|ZP_00881462.1\| General secretion pathway L [Shewanella sp. MR-4], gi\|82406194\|gb\|EAP... gi\|78506862, gi\|... - gi\|78685484\|ref\|ZP_00850262.1\| General secretion pathway L [Shewanella sp. ANA-3], gi\|78506862\|gb\|EA...	406.0	[0..1]	[395..1]
gi\|37678406, gi\|... - gi\|37678406\|ref\|NP_933015.1\| type II secretory pathway, component EpsL [Vibrio vulnificus YJ016], gi...	406.0	[0..1]	[395..1]
gi\|120560578, gi... - gi\|82741854\|ref\|ZP_00904565.1\| General secretion pathway L [Shewanella sp. W3-18-1], gi\|82720785\|gb\|...	391.0	[0..1]	[395..1]
gi\|77813394, gi\|... - gi\|77813394\|ref\|ZP_00812669.1\| General secretion pathway L [Shewanella putrefaciens CN-32], gi\|77811...	390.0	[0..1]	[395..1]
gi\|28896915, gi\|... - gi\|28896915\|ref\|NP_796520.1\| general secretion pathway protein L [Vibrio parahaemolyticus RIMD 22106... gi\|28805123 - gi\|28805123\|dbj\|BAC58404.1\| general secretion pathway protein L [Vibrio parahaemolyticus RIMD 221063...	382.0	[0..1]	[395..5]
gi\|91190223, gi\|... - gi\|91224977\|ref\|ZP_01260236.1\| general secretion pathway protein L [Vibrio alginolyticus 12G01], gi\|...	379.0	[0..1]	[394..1]
gi\|27364317, gi\|... - gi\|27364317\|ref\|NP_759845.1\| Type II secretory pathway, component EpsL [Vibrio vulnificus CMCP6], gi...	378.0	[0..20]	[395..1]
gi\|126176383, gi... - gi\|68541296\|ref\|ZP_00581041.1\| General secretion pathway L [Shewanella baltica OS155], gi\|68520949\|g...	377.0	[0..1]	[395..1]
gi\|113909624, gi... - gi\|160873287\|ref\|YP_001552603.1\| general secretion pathway protein L [Shewanella baltica OS195], gi\|...	377.0	[0..1]	[395..1]

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Predicted Domain #1

Region A:
Residues: [1-233]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MSERLFIRLG RTAEQACSWL VWSEQEQEII ASGELANAQG LSTLTERAGN RPIDVLVPAS  60
   61 AMTLTSVNLP EKGQRQALKA LPFMLEESIA DDVDAMHFTV GPRNGDALSV VAVAHEQMQT 120
  121 WLSCLADAGL KVKRIVPDCL ALPLQECQWA AMRFGNELLL RTGLGTGHSL PLPWLPVAMK 180
  181 QLTAQAEELS VASYSEMQLD GVELKPQPLD LPMLVLARGI LHAPINLLSG VYT

[Run NCBI BLAST on this sequence.]

Detection Method:	PSI-BLAST
Confidence:	56.69897
Match:	1w97L
Description:	cyto-EpsL: the cytoplasmic domain of EpsL, an inner membrane component of the type II secretion system of Vibrio cholerae
Matching Structure (courtesy of the PDB):

Predicted functions:

Term	Confidence	Notes
protein transporter activity	4.02866382720893	bayes_pls_golite062009
protein binding	1.35507414089234	bayes_pls_golite062009
binding	1.02845327471562	bayes_pls_golite062009
hydrolase activity, acting on acid anhydrides	0.900931843471417	bayes_pls_golite062009
hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides	0.898645342556399	bayes_pls_golite062009
pyrophosphatase activity	0.875671218597808	bayes_pls_golite062009
nucleoside-triphosphatase activity	0.78242344952806	bayes_pls_golite062009
transporter activity	0.765123574918886	bayes_pls_golite062009
ATPase activity	0.687771333492666	bayes_pls_golite062009
unfolded protein binding	0.280566495830281	bayes_pls_golite062009
substrate-specific transporter activity	0.182906814232639	bayes_pls_golite062009

Predicted Domain #2

Region A:
Residues: [234-331]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 PKREYSKHLL QWKNAAIVLA VAIVLSLVNK GLTIHQVNGQ IADLKAQSEA IYQQVVPGNT  60
   61 RIVNLRSQME SQLRSLQGQG SGAEFFSMLA GLQDAFKQ

[Run NCBI BLAST on this sequence.]

Detection Method:

deduced

Shown below is our most confident de novo (Rosetta) prediction for this domain.
Click here to view all matches.

Found no confident structure predictions for this domain.

Predicted Domain #3

Region A:
Residues: [332-395]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 VPELKPNSLR FESARNEIRM QVTAKNYAQI EKFKEIVGRR FQMDGGTMNS GEDQVTSTLT  60
   61 LRSK

[Run NCBI BLAST on this sequence.]

Detection Method:

MSA

Shown below is our most confident prediction for this domain.
Click here to view all matches.

		MCM Score	GO Score	GO Term	SCOP Match	SCOP Description
View	Download	0.898	0.049	protein transporter activity	d.15.7	Immunoglobulin-binding domains

TMHMM	2.0c	PSIPRED	v2.61
SignalP	3.0	COILS	1999
DISOPRED	v0.1	NCBI nr	06/2007
PSI-BLAST	2.2.18	FFAS	ffas03
PDB	06/2007	Pfam	22
HMMER	2.3.2

View Structure Prediction Details

Top Sequence Alignment Hits

Predicted functions: