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View Structure Prediction Details

Protein: YRF14_YEAST
Organism: Saccharomyces cerevisiae S288c
Length: 1382 amino acids
Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16



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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for YRF14_YEAST.

Description E-value Query
Range
Subject
Range
gi|7507776 - gi|7507776|pir||T16867 probable cytochrome P450 T13C5.1 [similarity] - Caenorhabditis elegans
0.0 [159..1382] [1..1224]
YRF1-2 - Helicase encoded by the Y' element of subtelomeric regions, highly expressed in the mutants lacking ...
YRF12_YEAST - Y' element ATP-dependent helicase protein 1 copy 2 OS=Saccharomyces cerevisiae (strain ATCC 204508 /...
0.0 [15..1382] [315..1681]

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Predicted Domain #1
Region A:
Residues: [1-93]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MWKTLGRVEQ LLPYASLILR NREVLFREPK RGIDEYLEND SFFQMIPVKY REIVLPKLRR  60
   61 DTNKMTAALK NKVAVAIDEL TVPLMWMIHF AVG

[Run NCBI BLAST on this sequence.]

Detection Method: MSA

Shown below is our most confident prediction for this domain.
Click here to view all matches.

Found no confident structure predictions for this domain.

Predicted Domain #2
Region A:
Residues: [94-173]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 YPYRYPELQL LAFAGPQRNV YVDDTTRRIQ LYTDYNKNGS SEPRLKTLDG LTSDYVFYFV  60
   61 TVLRQMQICA LGNSYDAFNH 

[Run NCBI BLAST on this sequence.]

Detection Method: deduced

Shown below is our most confident de novo (Rosetta) prediction for this domain.
Click here to view all matches.

Found no confident structure predictions for this domain.

Predicted functions:

Term Confidence Notes
binding 0.36550713198424 bayes_pls_golite062009
catalytic activity 0.234613562021476 bayes_pls_golite062009
nucleoside-triphosphatase activity 0.166100211611062 bayes_pls_golite062009
pyrophosphatase activity 0.159702441149605 bayes_pls_golite062009
hydrolase activity, acting on acid anhydrides 0.149170905385965 bayes_pls_golite062009
hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides 0.147838751017739 bayes_pls_golite062009
hydrolase activity 0.0436758932827116 bayes_pls_golite062009

Predicted Domain #3
Region A:
Residues: [174-314]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 DPWMDVVGFE DPDQVTNRDI SRIVLYSYMF LNTAKGCLVE YATFRQYMRE LPKNAPQKLN  60
   61 FREMRQGLIA LGRHCVGSRF ETDLYESATS ELMANHSVQT GRNIYGVDSF SLTSVSGTTA 120
  121 TLLQERASER WIQWLGLESD Y

[Run NCBI BLAST on this sequence.]

Detection Method: MSA

Shown below is our most confident prediction for this domain.
Click here to view all matches.

Found no confident structure predictions for this domain.

Predicted Domain #4
Region A:
Residues: [315-778]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 HCSFSSTRNA EDVVAGEAAS SDHHQKISRV TRKRPREPKS TNDILVAGRK LFGSSFEFRD  60
   61 LHQLRLCHEI YMADTPSVAV QAPPGYGKTE LFHLPLIALA SKGDVKYVSF LFVPYTVLLA 120
  121 NCMIRLSRCG CLNVAPVRNF IEEGCDGVTD LYVGIYDDLA STNFTDRIAA WENIVECTFR 180
  181 TNNVKLGYLI VDEFHNFETE VYRQSQFGGI TNLDFDAFEK AIFLSGTAPE AVADAALQRI 240
  241 GLTGLAKKSM DINELKRSED LSRGLSSYPT RMFNLIKEKS EVPLGHVHKI WKKVESQPEE 300
  301 ALKLLLALFE IEPESKAIVV ASTTNEVEEL ACSWRKYFRV VWIHGKLGAA EKVSRTKEFV 360
  361 TDGSMRVLIG TKLVTEGIDI KQLMMVIMLD NRLNIIELIQ GVGRLRDGGL CYLLSRKNSW 420
  421 AARNRKGELP PIKEGCITEQ VREFYGLESK KGKKGQHVGC CGSR

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 168.0
Match: 1fuuA_
Description: Initiation factor 4a
Matching Structure (courtesy of the PDB):

Predicted Domain #5
Region A:
Residues: [779-1007]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 TDLSADTVEL IERMDRLAEK QATASMSIIA LPSSFQESNS SDRCRKYCSS DEDSDTCIHG  60
   61 SANASTNATT NSSTNATTTA STNVRTSATT TASINVRTSA ITTESTNSST NATTTASTNV 120
  121 RTSATTTASI NVRTSATTTE STNSNTSATT TESTDSNTSA TTTESTDSNT SATTTASTNS 180
  181 STNATTTAST NSSTNATTTE STNASAKEDA NKDGNAEDNR FHPVTDINK

[Run NCBI BLAST on this sequence.]

Detection Method: MSA

Shown below is our most confident prediction for this domain.
Click here to view all matches.

Found no confident structure predictions for this domain.

Predicted Domain #6
Region A:
Residues: [1008-1382]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 ESYKRKGSQM VLLERKKLKA QFPNTSENMN VLQFLGFRSD EIKHLFLYGI DVYFCPEGVF  60
   61 TQYGLCKGCQ KMFELCVCWA GQKVSYRRMA WEALAVERML RNDEEYKEYL EDIEPYHGDP 120
  121 VGYLKYFSVK RGEIYSQIQR NYAWYLAITR RRETISVLDS TRGKQGSQVF RMSGRQIKEL 180
  181 YYKVWSNLRE SKTEVLQYFL NWDEKKCREE WEAKDDTVFV EALEKVGVFQ RLRSMTSAGL 240
  241 QGPQYVKLQF SRHHRQLRSR YELSLGMHLR DQLALGVTPS KVPHWTAFLS MLIGLFYNKT 300
  301 FRQKLEYLLE QISEVWLLPH WLDLANVEVL AADNTRVPLY MLMVAVHKEL DSDDVPDGRF 360
  361 DIILLCRDSS REVGE

[Run NCBI BLAST on this sequence.]

Detection Method: deduced

Shown below is our most confident de novo (Rosetta) prediction for this domain.
Click here to view all matches.

Found no confident structure predictions for this domain.


YRC Informatics Platform - Version 3.0
Created and Maintained by: Michael Riffle