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View Structure Prediction Details

Protein: YP199_YEAST
Organism: Saccharomyces cerevisiae S288c
Length: 240 amino acids
Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16



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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for YP199_YEAST.

Description E-value Query
Range
Subject
Range
YPL199C - Putative protein of unknown function, predicted to be palmitoylated
gi|190407763 - gi|190407763|gb|EDV11028.1| conserved hypothetical protein [Saccharomyces cerevisiae RM11-1a]
gi|151942601 - gi|151942601|gb|EDN60947.1| conserved protein [Saccharomyces cerevisiae YJM789]
YP199_YEAST - Smr domain-containing protein YPL199C OS=Saccharomyces cerevisiae (strain ATCC 204508 / S288c) GN=YP...
gi|207340698 - gi|207340698|gb|EDZ68968.1| YPL199Cp-like protein [Saccharomyces cerevisiae AWRI1631]
2.0E-85 [1..240] [1..240]
YLL3_SCHPO - Smr domain-containing protein C11H11.03c OS=Schizosaccharomyces pombe (strain 972 / ATCC 24843) GN=S...
SPAC11H11.03c - SMR and DUF1771 domain protein
2.0E-50 [24..196] [2..175]
N4BP2 - NEDD4 binding protein 2
1.0E-49 [10..171] [1602..1770]
gi|32403552, gi|... - gi|32403552|ref|XP_322389.1| hypothetical protein [Neurospora crassa], gi|28918869|gb|EAA28538.1| pr...
gi|85086875 - gi|85086875|ref|XP_957774.1| hypothetical protein NCU00303 [Neurospora crassa OR74A]
1.0E-48 [21..203] [20..200]
Y5872_ARATH - SMR domain-containing protein At5g58720 OS=Arabidopsis thaliana GN=PIPC PE=1 SV=1
2.0E-43 [6..174] [334..503]

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Predicted Domain #1
Region A:
Residues: [1-92]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MKGTGGVVVG TQNPVRDYNH STDEEYQRLR RLADEAYKKR DQLSHESQTA YQQGDKKLAH  60
   61 ELSEKSKAQL KTAEDFNMQA AEYVFVENNA DS

[Run NCBI BLAST on this sequence.]

Detection Method: deduced

Shown below are all of our de novo (Rosetta) predictions for this domain.
Click here to view only most confident match.

    MCM
Score
GO
Score
GO
Term
SCOP
Match
SCOP Description
View Download 0.945 0.000 cytoplasm a.7.1 Spectrin repeat
View Download 0.935 0.000 cytoplasm a.2.11 Fe,Mn superoxide dismutase (SOD), N-terminal domain
View Download 0.971 0.000 cytoplasm f.17.1 F1F0 ATP synthase subunit C
View Download 0.927 0.000 cytoplasm a.2.8 Eukaryotic DNA topoisomerase I, dispensable insert domain
View Download 0.971 0.000 cytoplasm f.17.1 F1F0 ATP synthase subunit C
View Download 0.945 0.000 cytoplasm a.7.1 Spectrin repeat
View Download 0.935 0.000 cytoplasm a.2.11 Fe,Mn superoxide dismutase (SOD), N-terminal domain
View Download 0.927 0.000 cytoplasm a.2.8 Eukaryotic DNA topoisomerase I, dispensable insert domain
View Download 0.919 0.000 cytoplasm a.7.1 Spectrin repeat
View Download 0.915 0.000 cytoplasm a.2.7 tRNA-binding arm
View Download 0.896 0.000 cytoplasm a.7.1 Spectrin repeat
View Download 0.878 0.000 cytoplasm a.47.2 t-snare proteins
View Download 0.866 0.000 cytoplasm a.2.1 GreA transcript cleavage protein, N-terminal domain
View Download 0.843 0.000 cytoplasm a.7.5 Tubulin chaperone cofactor A
View Download 0.834 0.000 cytoplasm a.24.2 Aspartate receptor, ligand-binding domain
View Download 0.803 0.000 cytoplasm f.17.2 Cytochrome c oxidase subunit II-like, transmembrane region
View Download 0.785 0.000 cytoplasm a.29.3 Acyl-CoA dehydrogenase C-terminal domain-like
View Download 0.784 0.000 cytoplasm i.1.1 Ribosome and ribosomal fragments
View Download 0.781 0.000 cytoplasm a.7.4 Smac/diablo
View Download 0.777 0.000 cytoplasm a.25.1 Ferritin-like
View Download 0.770 0.000 cytoplasm a.7.2 Enzyme IIa from lactose specific PTS, IIa-lac
View Download 0.758 0.000 cytoplasm a.2.7 tRNA-binding arm
View Download 0.756 0.000 cytoplasm a.23.1 HSC20 (HSCB), C-terminal oligomerisation domain
View Download 0.747 0.000 cytoplasm a.24.14 FAT domain of focal adhesion kinase
View Download 0.734 0.000 cytoplasm a.29.3 Acyl-CoA dehydrogenase C-terminal domain-like
View Download 0.720 0.000 cytoplasm a.4.5 "Winged helix" DNA-binding domain
View Download 0.701 0.000 cytoplasm a.7.7 BAG domain
View Download 0.700 0.000 cytoplasm a.47.2 t-snare proteins
View Download 0.696 0.000 cytoplasm a.24.1 Apolipoprotein
View Download 0.692 0.000 cytoplasm f.25.1 Cytochrome c oxidase subunit III-like
View Download 0.681 0.000 cytoplasm a.24.9 alpha-catenin/vinculin
View Download 0.676 0.000 cytoplasm a.29.2 Bromodomain
View Download 0.657 0.000 cytoplasm a.2.5 Prefoldin
View Download 0.652 0.000 cytoplasm a.25.1 Ferritin-like
View Download 0.649 0.000 cytoplasm a.2.7 tRNA-binding arm
View Download 0.622 0.000 cytoplasm a.24.17 Group V grass pollen allergen
View Download 0.621 0.000 cytoplasm a.30.2 Homodimeric domain of signal transducing histidine kinase
View Download 0.617 0.000 cytoplasm a.13.1 alpha-2-Macroglobulin receptor associated protein (RAP) domain 1
View Download 0.616 0.000 cytoplasm d.67.3 Ribosome recycling factor, RRF
View Download 0.615 0.000 cytoplasm a.25.1 Ferritin-like
View Download 0.588 0.000 cytoplasm a.2.7 tRNA-binding arm
View Download 0.587 0.000 cytoplasm a.2.5 Prefoldin
View Download 0.566 0.000 cytoplasm a.2.11 Fe,Mn superoxide dismutase (SOD), N-terminal domain
View Download 0.535 0.000 cytoplasm a.25.1 Ferritin-like
View Download 0.529 0.000 cytoplasm f.14.1 Voltage-gated potassium channels
View Download 0.525 0.000 cytoplasm f.13.1 Family A G protein-coupled receptor-like
View Download 0.519 0.000 cytoplasm a.51.1 Cytochrome c oxidase subunit h
View Download 0.516 0.000 cytoplasm f.28.1 Nonheme 11 kDa protein of cytochrome bc1 complex (Ubiquinol-cytochrome c reductase)
View Download 0.513 0.000 cytoplasm a.30.2 Homodimeric domain of signal transducing histidine kinase
View Download 0.487 0.000 cytoplasm a.62.1 Hepatitis B viral capsid (hbcag)
View Download 0.480 0.000 cytoplasm a.46.1 Methionine synthase domain
View Download 0.478 0.000 cytoplasm a.7.6 Ribosomal protein S20
View Download 0.476 0.000 cytoplasm a.45.1 Glutathione S-transferase (GST), C-terminal domain
View Download 0.470 0.000 cytoplasm a.25.1 Ferritin-like
View Download 0.454 0.000 cytoplasm a.7.8 GAT domain
View Download 0.453 0.000 cytoplasm a.63.1 Apolipophorin-III
View Download 0.451 0.000 cytoplasm a.30.1 ROP protein
View Download 0.449 0.000 cytoplasm a.59.1 PAH2 domain
View Download 0.432 0.000 cytoplasm a.47.2 t-snare proteins
View Download 0.431 0.000 cytoplasm a.2.3 Chaperone J-domain
View Download 0.424 0.000 cytoplasm f.17.2 Cytochrome c oxidase subunit II-like, transmembrane region
View Download 0.421 0.000 cytoplasm a.165.1 Myosin phosphatase inhibitor 17kDa protein, CPI-17
View Download 0.421 0.000 cytoplasm f.15.1 Small-conductance potassium channel
View Download 0.410 0.000 cytoplasm f.32.1 a domain/subunit of cytochrome bc1 complex (Ubiquinol-cytochrome c reductase)
View Download 0.397 0.000 cytoplasm f.36.1 Neurotransmitter-gated ion-channel pransmembrane pore
View Download 0.395 0.000 cytoplasm a.24.4 Hemerythrin
View Download 0.381 0.000 cytoplasm a.29.2 Bromodomain
View Download 0.377 0.000 cytoplasm a.26.1 4-helical cytokines
View Download 0.377 0.000 cytoplasm f.1.3 delta-Endotoxin (insectocide), N-terminal domain
View Download 0.367 0.000 cytoplasm a.118.7 14-3-3 protein
View Download 0.360 0.000 cytoplasm a.24.11 Bacterial GAP domain
View Download 0.342 0.000 cytoplasm a.118.14 FliG
View Download 0.340 0.000 cytoplasm a.7.1 Spectrin repeat
View Download 0.338 0.000 cytoplasm g.44.1 RING/U-box
View Download 0.337 0.000 cytoplasm a.118.10 Phosphoinositide-binding clathrin adaptor, N-terminal domain
View Download 0.337 0.000 cytoplasm a.29.5 alpha-ketoacid dehydrogenase kinase, N-terminal domain
View Download 0.335 0.000 cytoplasm a.27.1 Anticodon-binding domain of a subclass of class I aminoacyl-tRNA synthetases
View Download 0.332 0.000 cytoplasm a.26.1 4-helical cytokines
View Download 0.326 0.000 cytoplasm a.8.2 Plasmid maintenance system epsilon/zeta, antidote epsilon subunit
View Download 0.325 0.000 cytoplasm e.20.1 Heat shock protein 70kD (HSP70), C-terminal substrate-binding fragment
View Download 0.324 0.000 cytoplasm a.133.1 Phospholipase A2, PLA2
View Download 0.323 0.000 cytoplasm d.58.44 Multidrug efflux transporter AcrB pore domain; PN1, PN2, PC1 and PC2 subdomains
View Download 0.323 0.000 cytoplasm a.133.1 Phospholipase A2, PLA2
View Download 0.323 0.000 cytoplasm a.27.1 Anticodon-binding domain of a subclass of class I aminoacyl-tRNA synthetases
View Download 0.320 0.000 cytoplasm d.58.12 eEF-1beta-like
View Download 0.319 0.000 cytoplasm f.28.1 Nonheme 11 kDa protein of cytochrome bc1 complex (Ubiquinol-cytochrome c reductase)
View Download 0.319 0.000 cytoplasm a.22.1 Histone-fold
View Download 0.304 0.000 cytoplasm a.24.9 alpha-catenin/vinculin
View Download 0.303 0.000 cytoplasm a.29.2 Bromodomain
View Download 0.298 0.000 cytoplasm a.24.9 alpha-catenin/vinculin
View Download 0.297 0.000 cytoplasm a.29.5 alpha-ketoacid dehydrogenase kinase, N-terminal domain
View Download 0.296 0.000 cytoplasm d.232.1 Mago nashi protein
View Download 0.294 0.000 cytoplasm a.37.1 A DNA-binding domain in eukaryotic transcription factors
View Download 0.289 0.000 cytoplasm a.16.1 S15/NS1 RNA-binding domain
View Download 0.287 0.000 cytoplasm a.22.1 Histone-fold
View Download 0.284 0.000 cytoplasm d.58.43 Mechanosensitive channel protein MscS (YggB), C-terminal domain
View Download 0.282 0.000 cytoplasm a.2.3 Chaperone J-domain
View Download 0.280 0.000 cytoplasm a.29.4 RecG, N-terminal domain
View Download 0.280 0.000 cytoplasm a.24.3 Cytochromes
View Download 0.275 0.000 cytoplasm f.18.1 F1F0 ATP synthase subunit A
View Download 0.271 0.000 cytoplasm a.45.1 Glutathione S-transferase (GST), C-terminal domain
View Download 0.270 0.000 cytoplasm a.118.8 TPR-like
View Download 0.269 0.000 cytoplasm a.16.1 S15/NS1 RNA-binding domain
View Download 0.268 0.000 cytoplasm a.2.9 C-terminal UvrC-binding domain of UvrB
View Download 0.260 0.000 cytoplasm a.118.16 Testis/brain RNA-binding protein (TB-RBP)
View Download 0.258 0.000 cytoplasm a.19.1 Fertilization protein
View Download 0.256 0.000 cytoplasm a.22.1 Histone-fold
View Download 0.251 0.000 cytoplasm a.7.7 BAG domain
View Download 0.247 0.000 cytoplasm f.21.2 Fumarate reductase respiratory complex transmembrane subunits
View Download 0.244 0.000 cytoplasm f.5.1 Integral outer membrane protein TolC, efflux pump component
View Download 0.242 0.000 cytoplasm f.13.1 Family A G protein-coupled receptor-like
View Download 0.241 0.000 cytoplasm a.64.1 Saposin
View Download 0.239 0.000 cytoplasm a.7.5 Tubulin chaperone cofactor A
View Download 0.239 0.000 cytoplasm a.4.1 Homeodomain-like
View Download 0.237 0.000 cytoplasm f.21.2 Fumarate reductase respiratory complex transmembrane subunits
View Download 0.237 0.000 cytoplasm f.34.1 Mechanosensitive channel protein MscS (YggB), transmembrane region
View Download 0.235 0.000 cytoplasm a.38.1 Helix-loop-helix DNA-binding domain
View Download 0.232 0.000 cytoplasm d.43.1 Elongation factor Ts (EF-Ts), dimerisation domain
View Download 0.231 0.000 cytoplasm d.58.26 GHMP Kinase, C-terminal domain
View Download 0.229 0.000 cytoplasm a.47.2 t-snare proteins
View Download 0.224 0.000 cytoplasm a.151.1 Glutamyl tRNA-reductase dimerization domain
View Download 0.224 0.000 cytoplasm b.88.1 Mss4-like
View Download 0.224 0.000 cytoplasm f.31.1 Photosystem I reaction center subunit XI, PsaL
View Download 0.212 0.000 cytoplasm a.63.1 Apolipophorin-III
View Download 0.206 0.000 cytoplasm d.74.3 RBP11-like subunits of RNA polymerase
View Download 0.203 0.000 cytoplasm a.118.1 ARM repeat

Predicted Domain #2
Region A:
Residues: [93-240]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 SSNEIDLHGL YVKEALFILQ KRIKFAIDHN EPQLNVIVGK GLHSQNGIAK LKPSIEEFCA  60
   61 KHGIRNHLEK GNSGVLVLEL QGVQMQMDGP AVNAPTNQYN AQPHPQYNNN GGQPQGQAQN 120
  121 YNNSGNDNKD STLTSIFKIF CNCIQSLA

[Run NCBI BLAST on this sequence.]

Detection Method: Pfam
Confidence: 27.769551
Match: PF01713
Description: Smr domain

Shown below are all of our structure predictions for this domain.
Click here to view only most confident match.

Found no structure predictions for this domain.

Predicted functions:

Term Confidence Notes
binding 0.780949548591104 bayes_pls_golite062009
protein binding 0.245678926103876 bayes_pls_golite062009

YRC Informatics Platform - Version 3.0
Created and Maintained by: Michael Riffle