YRC Public Data Repository - Protein Structure Prediction

Protein:	VIP1_YEAST
Organism:	Saccharomyces cerevisiae S288c
Length:	1146 amino acids
Reference:	Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16

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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for VIP1_YEAST.

Description	E-value	Query Range	Subject Range
VIP1_YEAST - Inositol hexakisphosphate and diphosphoinositol-pentakisphosphate kinase OS=Saccharomyces cerevisiae... VIP1 - Inositol hexakisphosphate (IP6) and inositol heptakisphosphate (IP7) kinase; generation of IP7 by Vi...	0.0	[1..1146]	[1..1146]
asp1 - inositol hexakisphosphate kinase /inositol pyrophosphate synthase VIP1_SCHPO - Inositol hexakisphosphate and diphosphoinositol-pentakisphosphate kinase OS=Schizosaccharomyces pomb...	0.0	[164..1105]	[10..919]
gi\|19352987, gi\|... - gi\|41281583\|ref\|NP_056031.2\| Histidine acid phosphatase domain containing 1 [Homo sapiens], gi\|19352...	0.0	[143..1049]	[2..896]
gi\|18417557, gi\|... - gi\|25054864\|gb\|AAN71921.1\| unknown protein [Arabidopsis thaliana], gi\|18417557\|ref\|NP_568308.1\| acid...	0.0	[186..1047]	[11..951]
gi\|7507776 - gi\|7507776\|pir\|\|T16867 probable cytochrome P450 T13C5.1 [similarity] - Caenorhabditis elegans	0.0	[185..1051]	[14..918]
gi\|167992127, gi... - gi\|205329573\|gb\|EDZ16337.1\| ribosomal protein S6 modification protein [Salmonella enterica subsp. en... gi\|205334855, gi... - gi\|205334855\|gb\|EDZ21619.1\| ribosomal protein S6 modification protein [Salmonella enterica subsp. en... gi\|205339833, gi... - gi\|205339833\|gb\|EDZ26597.1\| ribosomal protein S6 modification protein [Salmonella enterica subsp. en... gi\|168263606, gi... - gi\|205347820\|gb\|EDZ34451.1\| ribosomal protein S6 modification protein [Salmonella enterica subsp. en... RIMK_SALPB - Ribosomal protein S6 modification protein OS=Salmonella paratyphi B (strain ATCC BAA-1250 / SPB7) GN... gi\|238913393 - gi\|238913393\|ref\|ZP_04657230.1\| ribosomal protein S6 modification protein [Salmonella enterica subsp... gi\|205324600, gi... - gi\|205324600\|gb\|EDZ12439.1\| ribosomal protein S6 modification protein [Salmonella enterica subsp. en... RIMK_SALTY - Ribosomal protein S6 modification protein OS=Salmonella typhimurium GN=rimK PE=3 SV=1 RIMK_SALCH - Ribosomal protein S6 modification protein OS=Salmonella choleraesuis GN=rimK PE=3 SV=1 RIMK_SALTI - Ribosomal protein S6--L-glutamate ligase OS=Salmonella typhi GN=rimK PE=3 SV=1 RIMK_SALTY - Ribosomal protein S6--L-glutamate ligase OS=Salmonella typhimurium (strain LT2 / SGSC1412 / ATCC 700... RIMK_SALTI - Ribosomal protein S6 modification protein OS=Salmonella typhi GN=rimK PE=3 SV=1 gi\|213428052 - gi\|213428052\|ref\|ZP_03360802.1\| ribosomal protein S6 modification protein [Salmonella enterica subsp... RIMK_SALCH - Ribosomal protein S6 modification protein OS=Salmonella choleraesuis GN=rimK PE=3 SV=1 gi\|213647771 - gi\|213647771\|ref\|ZP_03377824.1\| ribosomal protein S6 modification protein [Salmonella enterica subsp... RIMK_SALPA - Ribosomal protein S6 modification protein OS=Salmonella paratyphi A GN=rimK PE=3 SV=1 gi\|213855199 - gi\|213855199\|ref\|ZP_03383439.1\| ribosomal protein S6 modification protein [Salmonella enterica subsp... gi\|214000354 - gi\|214000354\|ref\|ZP_03411089.1\| ribosomal protein S6 modification protein [Salmonella enterica subsp... gi\|204929913, gi... - gi\|204929913\|ref\|ZP_03220934.1\| ribosomal protein S6 modification protein [Salmonella enterica subsp... RIMK_SALCH - Ribosomal protein S6--L-glutamate ligase OS=Salmonella choleraesuis (strain SC-B67) GN=rimK PE=3 SV=... RIMK_SALG2 - Ribosomal protein S6--L-glutamate ligase OS=Salmonella gallinarum (strain 287/91 / NCTC 13346) GN=ri... RIMK_SALPA - Ribosomal protein S6--L-glutamate ligase OS=Salmonella paratyphi A (strain ATCC 9150 / SARB42) GN=ri... RIMK_SALEP - Ribosomal protein S6--L-glutamate ligase OS=Salmonella enteritidis PT4 (strain P125109) GN=rimK PE=3... gi\|213163504 - gi\|213163504\|ref\|ZP_03349214.1\| ribosomal protein S6 modification protein [Salmonella enterica subsp... RIMK_SALA4 - Ribosomal protein S6--L-glutamate ligase OS=Salmonella agona (strain SL483) GN=rimK PE=3 SV=1 RIMK_SALTY - Ribosomal protein S6 modification protein OS=Salmonella typhimurium GN=rimK PE=3 SV=1 RIMK_SALPK - Ribosomal protein S6--L-glutamate ligase OS=Salmonella paratyphi A (strain AKU_12601) GN=rimK PE=3 S... RIMK_SALDC - Ribosomal protein S6--L-glutamate ligase OS=Salmonella dublin (strain CT_02021853) GN=rimK PE=3 SV=1 gi\|200389905, gi... - gi\|200389905\|ref\|ZP_03216516.1\| ribosomal protein S6 modification protein [Salmonella enterica subsp... gi\|168819962, gi... - gi\|205343131\|gb\|EDZ29895.1\| ribosomal protein S6 modification protein [Salmonella enterica subsp. en... RIMK_SALNS - Ribosomal protein S6--L-glutamate ligase OS=Salmonella newport (strain SL254) GN=rimK PE=3 SV=1 RIMK_SALHS - Ribosomal protein S6--L-glutamate ligase OS=Salmonella heidelberg (strain SL476) GN=rimK PE=3 SV=1 gi\|194472604, gi... - gi\|194472604\|ref\|ZP_03078588.1\| ribosomal protein S6 modification protein [Salmonella enterica subsp... RIMK_SALPC - Ribosomal protein S6--L-glutamate ligase OS=Salmonella paratyphi C (strain RKS4594) GN=rimK PE=3 SV=... RIMK_SALPB - Ribosomal protein S6--L-glutamate ligase OS=Salmonella paratyphi B (strain ATCC BAA-1250 / SPB7) GN=... gi\|29138072, gi\|... - gi\|29142442\|ref\|NP_805784.1\| ribosomal protein S6 modification protein [Salmonella enterica subsp. e... gi\|16759785 - gi\|16759785\|ref\|NP_455402.1\| ribosomal protein S6 modification protein [Salmonella enterica subsp. e... lcl\|NC_016856.1_... - [gene=rimK] [protein=ribosomal protein S6 modification protein] [protein_id=YP_005236617.1] [locatio...	1.0E-47	[281..522]	[76..293]

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Predicted Domain #1

Region A:
Residues: [1-234]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MSGIKKEPIE SDEVPQQETK NNLPSAPSEM SPLFLNKNTQ KAMQSIAPIL EGFSPKTSAS  60
   61 ENMSLKLPPP GIQDDHSEEN LTVHDTLQRT ISTALGNGNN TNTVTTSGLK KADSESKSEA 120
  121 DPEGLSNSNI VNDADNINSI SKTGSPHLPQ GTMDAEQTNM GTNSVPTSSA SSRKSSTSHP 180
  181 KPRLPKVGKI GVCAMDAKVL SKPMRHILNR LIEHGEFETV IFGDKVILDE RIEN

[Run NCBI BLAST on this sequence.]

Detection Method:

deduced

Shown below is our most confident de novo (Rosetta) prediction for this domain.
Click here to view all matches.

Found no confident structure predictions for this domain.

Predicted Domain #2

Region A:
Residues: [235-520]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 WPTCDFLISF FSSGFPLDKA IKYVKLRKPF IINDLIMQKI LWDRRLCLQV LEAYNVPTPP  60
   61 RLEISRDGGP RANEELRAKL REHGVEVKPV EEPEWKMVDD DTLEVDGKTM TKPFVEKPVD 120
  121 GEDHNIYIYY HSKNGGGGRR LFRKVGNKSS EFDPTLVHPR TEGSYIYEQF MDTDNFEDVK 180
  181 AYTIGENFCH AETRKSPVVD GIVRRNTHGK EVRYITELSD EEKTIAGKVS KAFSQMICGF 240
  241 DLLRVSGKSY VIDVNGFSFV KDNKAYYDSC ANILRSTFIE AKKKMD

[Run NCBI BLAST on this sequence.]

Detection Method:	PSI-BLAST
Confidence:	41.522879
Match:	2dln__
Description:	D-Ala-D-Ala ligase, N-domain; D-ala-D-ala ligase, C-domain
Matching Structure (courtesy of the PDB):

Predicted Domain #3

Region A:
Residues: [521-549]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MEKKNLPIIR EEKEQKWVFK GLAIIIRHA

[Run NCBI BLAST on this sequence.]

Region B:
Residues: [654-748]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 KYQATELGEQ MRQDFDLLNK SILQNIKIFS SSERRVLHTA QYWTRALFGA DELGSDEISI  60
   61 RKDLLDDSNA AKDLMDKVKK KLKPLLREGK EAPPQ

[Run NCBI BLAST on this sequence.]

Detection Method:	ORFEUS
Confidence:	8.82
Match:	1qfxA
Description:	Phytase (myo-inositol-hexakisphosphate-3-phosphohydrolase)
Matching Structure (courtesy of the PDB):

Predicted Domain #4

Region A:
Residues: [550-653]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 DRTPKQKFKH SFTSPIFISL LKGHKEEVVI RNVNDLKIVL QALRIALDEK AGNPAKIKVL  60
   61 ANALEKKLNF PGTKIQLKPV LNKENEVEKV QFILKWGGEP THSA

[Run NCBI BLAST on this sequence.]

Detection Method:	ORFEUS
Confidence:	8.82
Match:	1qfxA
Description:	Phytase (myo-inositol-hexakisphosphate-3-phosphohydrolase)
Matching Structure (courtesy of the PDB):

Predicted Domain #5

Region A:
Residues: [749-1146]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 FAWPSKMPEP YLVIKRVVEL MNYHKKIMDN NFAKKDVNSM QTRWCTSEDP SLFKERWDKL  60
   61 FKEFNNAEKV DPSKISELYD TMKYDALHNR QFLENIFDPG LPNEAIADEL GSHSLVDRYP 120
  121 INVLAKNNFK IIDSHSMNNS GKNSSNSVGS LGWVLESGKT STARNPKSSS QFDEPRFMQL 180
  181 RELYKLAKVL FDFICPKEYG ISDAEKLDIG LLTSLPLAKQ ILNDIGDMKN RETPACVAYF 240
  241 TKESHIYTLL NIIYESGIPM RIARNALPEL DYLSQITFEL YESTDASGQK SHSIRLKMSP 300
  301 GCHTQDPLDV QLDDRHYISC IPKISLTKHL DMDYVQQKLR NKFTRVIMPP KFTPVNITSP 360
  361 NLSFQKRKTR RKSVSVEKLK RPASSGSSSS TSVNKTLD

[Run NCBI BLAST on this sequence.]

Detection Method:

deduced

Shown below is our most confident de novo (Rosetta) prediction for this domain.
Click here to view all matches.

Found no confident structure predictions for this domain.

TMHMM	2.0c	PSIPRED	v2.61
SignalP	3.0	COILS	1999
DISOPRED	v0.1	NCBI nr	06/2007
PSI-BLAST	2.2.18	FFAS	ffas03
PDB	06/2007	Pfam	22
HMMER	2.3.2

View Structure Prediction Details

Top Sequence Alignment Hits