YRC Public Data Repository - Protein Structure Prediction

Protein:	NOT5_YEAST
Organism:	Saccharomyces cerevisiae S288c
Length:	560 amino acids
Reference:	Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16

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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for NOT5_YEAST.

Description	E-value	Query Range	Subject Range
NOT5_YEAST - General negative regulator of transcription subunit 5 OS=Saccharomyces cerevisiae (strain ATCC 20450... NOT5 - Subunit of the CCR4-NOT complex, which is a global transcriptional regulator with roles in transcrip...	0.0	[1..560]	[1..560]
gi\|109097758 - gi\|109097758\|ref\|XP_001117427.1\| PREDICTED: CCR4-NOT transcription complex, subunit 2 isoform 2 [Mac... gi\|7020899 - gi\|7020899\|dbj\|BAA91313.1\| unnamed protein product [Homo sapiens]	1.0E-71	[183..559]	[36..473]
gi\|85075997 - gi\|85075997\|ref\|XP_955865.1\| hypothetical protein NCU03855 [Neurospora crassa OR74A] gi\|32405122, gi\|... - gi\|32405122\|ref\|XP_323174.1\| hypothetical protein [Neurospora crassa], gi\|28916889\|gb\|EAA26629.1\| hy...	1.0E-71	[1..558]	[1..639]
NOT3_SCHPO - General negative regulator of transcription subunit 3 OS=Schizosaccharomyces pombe (strain 972 / ATC... SPAC1B3.05 - CCR4-Not complex subunit Not3 /5	2.0E-67	[19..559]	[9..626]
gi\|21312480, gi\|... - gi\|21312480\|ref\|NP_082358.1\| CCR4-NOT transcription complex, subunit 2 isoform b [Mus musculus], gi\|... gi\|149066929, gi... - gi\|149066932\|gb\|EDM16665.1\| rCG48666, isoform CRA_a [Rattus norvegicus], gi\|149066929\|gb\|EDM16662.1\|...	2.0E-65	[272..559]	[146..438]
ntl-2 - status:Confirmed UniProt:Q10923 protein_id:AAA80691.1	2.0E-56	[214..559]	[1..352]

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Predicted Domain #1

Region A:
Residues: [1-260]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MSQRKLQQDI DKLLKKVKEG IEDFDDIYEK FQSTDPSNSS HREKLESDLK REIKKLQKHR  60
   61 DQIKTWLSKE DVKDKQSVLM TNRRLIENGM ERFKSVEKLM KTKQFSKEAL TNPDIIKDPK 120
  121 ELKKRDQVLF IHDCLDELQK QLEQYEAQEN EEQTERHEFH IANLENILKK LQNNEMDPEP 180
  181 VEEFQDDIKY YVENNDDPDF IEYDTIYEDM GCEIQPSSSN NEAPKEGNNQ TSLSSIRSSK 240
  241 KQERSPKKKA PQRDVSISDR

[Run NCBI BLAST on this sequence.]

Detection Method:	PSI-BLAST
Confidence:	22.221849
Match:	1i84S_
Description:	Heavy meromyosin subfragment
Matching Structure (courtesy of the PDB):

Predicted Domain #2

Region A:
Residues: [261-560]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 ATTPIAPGVE SASQSISSTP TPVSTDTPLH TVKDDSIKFD NSTLGTPTTH VSMKKKESEN  60
   61 DSEQQLNFPP DRTDEIRKTI QHDVETNAAF QNPLFNDELK YWLDSKRYLM QPLQEMSPKM 120
  121 VSQLESSLLN CPDSLDADSP CLYTKPLSLP HPTSIFFPNE PIRFVYPYDV PLNLTNNEND 180
  181 TDNKFGKDSK AKSKKDDDIY SRTSLARIFM KFDLDTLFFI FYHYQGSYEQ FLAARELFKN 240
  241 RNWLFNKVDR CWYYKEIEKL PPGMGKSEEE SWRYFDYKKS WLARRCGNDF VYNEEDFEKL 300
  301

[Run NCBI BLAST on this sequence.]

Detection Method:

MSA

Shown below is our most confident prediction for this domain.
Click here to view all matches.

Found no confident structure predictions for this domain.

TMHMM	2.0c	PSIPRED	v2.61
SignalP	3.0	COILS	1999
DISOPRED	v0.1	NCBI nr	06/2007
PSI-BLAST	2.2.18	FFAS	ffas03
PDB	06/2007	Pfam	22
HMMER	2.3.2

View Structure Prediction Details

Top Sequence Alignment Hits