| Protein: | MTHR2_YEAST |
| Organism: | Saccharomyces cerevisiae S288c |
| Length: | 600 amino acids |
| Reference: | Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16 |
Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for MTHR2_YEAST.
| Description | E-value | Query Range |
Subject Range |
|
|
0.0 | [1..600] | [1..600] |
|
|
0.0 | [1..590] | [1..588] |
|
|
0.0 | [1..600] | [1..584] |
|
|
0.0 | [1..590] | [1..586] |
|
|
0.0 | [1..596] | [1..580] |
|
|
0.0 | [1..590] | [1..586] |
|
|
0.0 | [1..590] | [1..586] |
|
|
0.0 | [2..596] | [67..659] |
|
Region A: Residues: [1-309] |
1 11 21 31 41 51
| | | | | |
1 MKITEKLEQH RQTSGKPTYS FEYFVPKTTQ GVQNLYDRMD RMYEASLPQF IDITWNAGGG 60
61 RLSHLSTDLV ATAQSVLGLE TCMHLTCTNM PISMIDDALE NAYHSGCQNI LALRGDPPRD 120
121 AENWTPVEGG FQYAKDLIKY IKSKYGDHFA IGVAGYPECH PELPNKDVKL DLEYLKQKID 180
181 AGGDFIITQM FYDVDNFINW CSQVRAAGMD VPIIPGIMPI TTYAAFLRRA QWGQISIPQH 240
241 FSSRLDPIKD DDELVRDIGT NLIVEMCQKL LDSGYVSHLH IYTMNLEKAP LMILERLNIL 300
301 PTESEFNAH
|
| Detection Method: |  |
| Confidence: | 94.39794 |
| Match: | 1v93A_ |
| Description: | 5,10-Methylenetetrahydrofolate Reductase from Thermus thermophilus HB8 |
Matching Structure (courtesy of the PDB): |
|
| Term | Confidence | Notes |
| methylenetetrahydrofolate reductase (NADPH) activity | 3.97406471031265 | bayes_pls_golite062009 |
| oxidoreductase activity, acting on the CH-NH group of donors | 3.43788898294589 | bayes_pls_golite062009 |
| oxidoreductase activity | 3.26500423104107 | bayes_pls_golite062009 |
| oxidoreductase activity, acting on the CH-NH group of donors, NAD or NADP as acceptor | 2.35093189018748 | bayes_pls_golite062009 |
| catalytic activity | 2.15527229494088 | bayes_pls_golite062009 |
| 1-pyrroline-5-carboxylate dehydrogenase activity | 2.11575302268542 | bayes_pls_golite062009 |
| binding | 1.55766253746824 | bayes_pls_golite062009 |
| transcription regulator activity | 0.413628997019645 | bayes_pls_golite062009 |
| nucleic acid binding | 0.385543917258092 | bayes_pls_golite062009 |
| protein binding | 0.229798056306674 | bayes_pls_golite062009 |
| DNA binding | 0.214617895050106 | bayes_pls_golite062009 |
|
Region A: Residues: [310-453] |
1 11 21 31 41 51
| | | | | |
1 PLAVLPWRKS LNPKRKNEEV RPIFWKRRPY SYVARTSQWA VDEFPNGRFG DSSSPAFGDL 60
61 DLCGSDLIRQ SANKCLELWS TPTSINDVAF LVINYLNGNL KCLPWSDIPI NDEINPIKAH 120
121 LIELNQHSII TINSQPQVNG IRSN
|
| Detection Method: | |
Shown below are all of our de novo (Rosetta) predictions for this domain.
Click here to view only most confident match.
| MCM Score |
GO Score |
GO Term |
SCOP Match |
SCOP Description | ||
| View | Download | 0.547 | 0.824 | methylenetetrahydrofolate reductase (NADPH) activity | c.37.1 | P-loop containing nucleoside triphosphate hydrolases |
|
Region A: Residues: [454-508] |
1 11 21 31 41 51
| | | | | |
1 DKIHGWGPKD GYVYQKQYLE FMLPKTKLPK LIDTLKNNEF LTYFAIDSQG DLLSN
|
| Detection Method: | |
Shown below are all of our de novo (Rosetta) predictions for this domain.
Click here to view only most confident match.
| MCM Score |
SCOP Match |
SCOP Description | ||
| View | Download | 0.518 | b.43.4 | Riboflavin synthase domain-like |
| View | Download | 0.748 | d.74.3 | RBP11-like subunits of RNA polymerase |
| View | Download | 0.586 | d.58.44 | Multidrug efflux transporter AcrB pore domain; PN1, PN2, PC1 and PC2 subdomains |
| View | Download | 0.649 | d.129.2 | Phosphoglucomutase, C-terminal domain |
| View | Download | 0.604 | d.74.5 | Hypothetical protein Yml108w |
|
Region A: Residues: [509-600] |
1 11 21 31 41 51
| | | | | |
1 HPDNSKSNAV TWGIFPGREI LQPTIVEKIS FLAWKEEFYH ILNEWKLNMN KYDKPHSAQF 60
61 IQSLIDDYCL VNIVDNDYIS PDDQIHSILL SL
|
| Detection Method: | |
Shown below are all of our de novo (Rosetta) predictions for this domain.
Click here to view only most confident match.
Found no structure predictions for this domain.
