| Protein: | KICH_YEAST |
| Organism: | Saccharomyces cerevisiae S288c |
| Length: | 582 amino acids |
| Reference: | Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16 |
Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for KICH_YEAST.
| Description | E-value | Query Range |
Subject Range |
|
|
0.0 | [1..582] | [1..582] |
|
|
0.0 | [4..566] | [1..496] |
|
|
0.0 | [110..516] | [74..432] |
|
|
1.0E-99 | [105..576] | [22..455] |
|
|
4.0E-99 | [81..521] | [21..383] |
|
|
4.0E-97 | [117..514] | [12..338] |
|
Region A: Residues: [1-143] |
1 11 21 31 41 51
| | | | | |
1 MVQESRPGSV RSYSVGYQAR SRSSSQRRHS LTRQRSSQRL IRTISIESDV SNITDDDDLR 60
61 AVNEGVAGVQ LDVSETANKG PRRASATDVT DSLGSTSSEY IEIPFVKETL DASLPSDYLK 120
121 QDILNLIQSL KISKWYNNKK IQP
|
| Detection Method: |  |
Shown below are all of our de novo (Rosetta) predictions for this domain.
Click here to view only most confident match.
| MCM Score |
SCOP Match |
SCOP Description | ||
| View | Download | 0.228 | d.20.1 | UBC-like |
|
Region A: Residues: [144-191] |
1 11 21 31 41 51
| | | | | |
1 VAQDMNLVKI SGAMTNAIFK VEYPKLPSLL LRIYGPNIDN IIDREYEL
|
|
Region B: Residues: [205-218] |
1 11 21 31 41 51
| | | | | |
1 SLYGCFVNGR FEQF
|
| Detection Method: | |
| Confidence: | 12.95 |
| Match: | 1j7iA |
| Description: | Type IIIa 3',5"-aminoglycoside phosphotransferase |
Matching Structure (courtesy of the PDB): |
|
| Term | Confidence | Notes |
| phosphotransferase activity, alcohol group as acceptor | 4.77705138922602 | bayes_pls_golite062009 |
| protein kinase activity | 4.68131600649845 | bayes_pls_golite062009 |
| kinase activity | 4.63102094866388 | bayes_pls_golite062009 |
| transferase activity, transferring phosphorus-containing groups | 4.26470104655954 | bayes_pls_golite062009 |
| protein serine/threonine kinase activity | 3.92556971928915 | bayes_pls_golite062009 |
| transferase activity | 3.27487631214089 | bayes_pls_golite062009 |
| binding | 2.31186607166478 | bayes_pls_golite062009 |
| ATP binding | 1.62950013799854 | bayes_pls_golite062009 |
| adenyl ribonucleotide binding | 1.59120412984243 | bayes_pls_golite062009 |
| adenyl nucleotide binding | 1.57251948653832 | bayes_pls_golite062009 |
| lipid kinase activity | 1.3504796246251 | bayes_pls_golite062009 |
| ribonucleotide binding | 1.32931505255952 | bayes_pls_golite062009 |
| purine ribonucleotide binding | 1.32676572752438 | bayes_pls_golite062009 |
| purine nucleotide binding | 1.31489723493061 | bayes_pls_golite062009 |
| nucleotide binding | 1.31339663939554 | bayes_pls_golite062009 |
| protein binding | 1.24858883313437 | bayes_pls_golite062009 |
| catalytic activity | 1.21655087018101 | bayes_pls_golite062009 |
| choline kinase activity | 1.18757364210199 | bayes_pls_golite062009 |
| phosphoinositide 3-kinase activity | 1.10484220525143 | bayes_pls_golite062009 |
| protein tyrosine kinase activity | 1.06634272225692 | bayes_pls_golite062009 |
| receptor signaling protein serine/threonine kinase activity | 1.05231366895645 | bayes_pls_golite062009 |
| 1-phosphatidylinositol-3-kinase activity | 1.04034573968654 | bayes_pls_golite062009 |
| inositol or phosphatidylinositol kinase activity | 0.97254836668426 | bayes_pls_golite062009 |
| receptor signaling protein activity | 0.957217569601377 | bayes_pls_golite062009 |
| ethanolamine kinase activity | 0.68804237112665 | bayes_pls_golite062009 |
| transmembrane receptor protein kinase activity | 0.380769480509274 | bayes_pls_golite062009 |
| protein serine/threonine/tyrosine kinase activity | 0.22871167092767 | bayes_pls_golite062009 |
| cyclin-dependent protein kinase activity | 0.185842548207239 | bayes_pls_golite062009 |
| magnesium ion binding | 0.134745748018448 | bayes_pls_golite062009 |
| MAP kinase kinase kinase activity | 0.0569871200546399 | bayes_pls_golite062009 |
| MAP kinase kinase activity | 0.04117702615323 | bayes_pls_golite062009 |
|
Region A: Residues: [192-204] |
1 11 21 31 41 51
| | | | | |
1 QILARLSLKN IGP
|
|
Region B: Residues: [219-363] |
1 11 21 31 41 51
| | | | | |
1 LENSKTLTKD DIRNWKNSQR IARRMKELHV GVPLLSSERK NGSACWQKIN QWLRTIEKVD 60
61 QWVGDPKNIE NSLLCENWSK FMDIVDRYHK WLISQEQGIE QVNKNLIFCH NDAQYGNLLF 120
121 TAPVMNTPSL YTAPSSTSLT SQSSS
|
| Detection Method: | |
| Confidence: | 12.95 |
| Match: | 1j7iA |
| Description: | Type IIIa 3',5"-aminoglycoside phosphotransferase |
| Matching Structure (courtesy of the PDB): |
|
|
Region A: Residues: [364-519] |
1 11 21 31 41 51
| | | | | |
1 LFPSSSNVIV DDIINPPKQE QSQDSKLVVI DFEYAGANPA AYDLANHLSE WMYDYNNAKA 60
61 PHQCHADRYP DKEQVLNFLY SYVSHLRGGA KEPIDEEVQR LYKSIIQWRP TVQLFWSLWA 120
121 ILQSGKLEKK EASTAITREE IGPNGKKYII KTEPES
|
| Detection Method: | |
Shown below are all of our structure predictions for this domain.
Click here to view only most confident match.
| MCM Score |
GO Score |
GO Term |
SCOP Match |
SCOP Description | ||
| View | Download | 0.347 | 0.003 | cytosol | a.24.9 | alpha-catenin/vinculin |
| View | Download | 0.417 | 0.002 | cytosol | a.41.1 | Domain of poly(ADP-ribose) polymerase |
| View | Download | 0.343 | 0.002 | cytosol | a.24.14 | FAT domain of focal adhesion kinase |
| View | Download | 0.305 | 0.000 | cytosol | f.18.1 | F1F0 ATP synthase subunit A |
| View | Download | 0.546 | N/A | N/A | f.35.1 | Multidrug efflux transporter AcrB transmembrane domain |
| View | Download | 0.297 | N/A | N/A | a.80.1 | DNA polymerase III clamp loader subunits, C-terminal domain |
| View | Download | 0.292 | N/A | N/A | a.25.1 | Ferritin-like |
| View | Download | 0.291 | N/A | N/A | a.24.9 | alpha-catenin/vinculin |
| View | Download | 0.288 | N/A | N/A | a.24.9 | alpha-catenin/vinculin |
| View | Download | 0.281 | N/A | N/A | a.22.1 | Histone-fold |
| View | Download | 0.274 | N/A | N/A | a.25.1 | Ferritin-like |
| View | Download | 0.272 | N/A | N/A | d.232.1 | Mago nashi protein |
| View | Download | 0.258 | N/A | N/A | a.4.5 | "Winged helix" DNA-binding domain |
| View | Download | 0.252 | N/A | N/A | f.25.1 | Cytochrome c oxidase subunit III-like |
| View | Download | 0.250 | N/A | N/A | a.24.14 | FAT domain of focal adhesion kinase |
| View | Download | 0.245 | N/A | N/A | g.52.1 | Inhibitor of apoptosis (IAP) repeat |
| View | Download | 0.239 | N/A | N/A | a.2.5 | Prefoldin |
| View | Download | 0.235 | N/A | N/A | d.54.1 | Enolase N-terminal domain-like |
| View | Download | 0.232 | N/A | N/A | a.7.4 | Smac/diablo |
| View | Download | 0.230 | N/A | N/A | a.29.3 | Acyl-CoA dehydrogenase C-terminal domain-like |
| View | Download | 0.227 | N/A | N/A | f.36.1 | Neurotransmitter-gated ion-channel pransmembrane pore |
| View | Download | 0.222 | N/A | N/A | f.36.1 | Neurotransmitter-gated ion-channel pransmembrane pore |
| View | Download | 0.219 | N/A | N/A | f.35.1 | Multidrug efflux transporter AcrB transmembrane domain |
| View | Download | 0.215 | N/A | N/A | d.232.1 | Mago nashi protein |
| View | Download | 0.209 | N/A | N/A | a.24.12 | Outer surface protein C (OspC) |
| View | Download | 0.208 | N/A | N/A | a.78.1 | Fatty acid responsive transcription factor FadR, C-terminal domain |
| View | Download | 0.205 | N/A | N/A | f.35.1 | Multidrug efflux transporter AcrB transmembrane domain |
| View | Download | 0.203 | N/A | N/A | a.4.5 | "Winged helix" DNA-binding domain |
| View | Download | 0.202 | N/A | N/A | a.24.9 | alpha-catenin/vinculin |
| View | Download | 0.201 | N/A | N/A | f.36.1 | Neurotransmitter-gated ion-channel pransmembrane pore |
| View | Download | 0.200 | N/A | N/A | d.110.4 | SNARE-like |
|
Region A: Residues: [520-582] |
1 11 21 31 41 51
| | | | | |
1 PEEDFVENDD EPEAGVSIDT FDYMAYGRDK IAVFWGDLIG LGIITEEECK NFSSFKFLDT 60
61 SYL
|
| Detection Method: | |
Shown below are all of our de novo (Rosetta) predictions for this domain.
Click here to view only most confident match.
| MCM Score |
SCOP Match |
SCOP Description | ||
| View | Download | 0.668 | a.60.1 | SAM/Pointed domain |
| View | Download | 0.606 | a.60.1 | SAM/Pointed domain |
| View | Download | 0.585 | a.60.1 | SAM/Pointed domain |
| View | Download | 0.527 | a.60.1 | SAM/Pointed domain |
| View | Download | 0.499 | a.60.1 | SAM/Pointed domain |
| View | Download | 0.481 | d.68.7 | R3H domain |
| View | Download | 0.476 | a.4.5 | "Winged helix" DNA-binding domain |
| View | Download | 0.395 | a.4.1 | Homeodomain-like |
| View | Download | 0.393 | a.60.1 | SAM/Pointed domain |
| View | Download | 0.381 | a.4.5 | "Winged helix" DNA-binding domain |
| View | Download | 0.358 | a.60.2 | RuvA domain 2-like |
| View | Download | 0.350 | a.4.5 | "Winged helix" DNA-binding domain |
| View | Download | 0.328 | a.4.1 | Homeodomain-like |
| View | Download | 0.325 | a.4.5 | "Winged helix" DNA-binding domain |
| View | Download | 0.291 | a.2.3 | Chaperone J-domain |
| View | Download | 0.283 | a.65.1 | Annexin |
| View | Download | 0.276 | a.28.3 | Retrovirus capsid protein C-terminal domain |
| View | Download | 0.233 | a.36.1 | Signal peptide-binding domain |
| View | Download | 0.226 | a.3.1 | Cytochrome c |
| View | Download | 0.222 | a.4.10 | N-terminal Zn binding domain of HIV integrase |
| View | Download | 0.214 | a.60.2 | RuvA domain 2-like |
| View | Download | 0.203 | a.60.2 | RuvA domain 2-like |
