| Protein: | IQG1_YEAST |
| Organism: | Saccharomyces cerevisiae S288c |
| Length: | 1495 amino acids |
| Reference: | Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16 |
Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for IQG1_YEAST.
| Description | E-value | Query Range |
Subject Range |
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0.0 | [1..1495] | [1..1495] |
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0.0 | [76..1490] | [8..1488] |
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0.0 | [606..1492] | [725..1657] |
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0.0 | [606..1492] | [725..1657] |
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0.0 | [581..1492] | [666..1618] |
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0.0 | [160..1028] | [382..1274] |
|
Region A: Residues: [1-86] |
1 11 21 31 41 51
| | | | | |
1 MTAYSGSPSK PGNNNSYLNR YVENLGTNVT PPLRPQSSSK INSSLNIASP SHLKTKTSAS 60
61 NSSATILSKK VESSVSKLKP SLPNKL
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| Detection Method: |  |
Shown below are all of our de novo (Rosetta) predictions for this domain.
Click here to view only most confident match.
| MCM Score |
SCOP Match |
SCOP Description | ||
| View | Download | 0.468 | a.1.1 | Globin-like |
| View | Download | 0.461 | a.35.1 | lambda repressor-like DNA-binding domains |
| View | Download | 0.490 | d.49.1 | Signal recognition particle alu RNA binding heterodimer, SRP9/14 |
| View | Download | 0.467 | a.4.9 | Polynucleotide phosphorylase/guanosine pentaphosphate synthase (PNPase/GPSI), domain 3 |
| View | Download | 0.500 | a.60.11 | Hypothetical protein YjbJ |
| View | Download | 0.432 | a.12.1 | Kix domain of CBP (creb binding protein) |
| View | Download | 0.394 | a.29.4 | RecG, N-terminal domain |
| View | Download | 0.346 | a.4.5 | "Winged helix" DNA-binding domain |
| View | Download | 0.340 | d.29.1 | Ribosomal protein L31e |
| View | Download | 0.338 | a.24.7 | FKBP12-rapamycin-binding domain of FKBP-rapamycin-associated protein (FRAP) |
| View | Download | 0.334 | a.56.1 | CO dehydrogenase ISP C-domain like |
| View | Download | 0.319 | a.60.5 | Barrier-to-autointegration factor, BAF |
| View | Download | 0.298 | a.24.17 | Group V grass pollen allergen |
| View | Download | 0.295 | a.36.1 | Signal peptide-binding domain |
| View | Download | 0.289 | a.144.1 | PABC (PABP) domain |
| View | Download | 0.282 | c.9.1 | Barstar (barnase inhibitor) |
| View | Download | 0.279 | c.102.1 | Cell-division inhibitor MinC, N-terminal domain |
| View | Download | 0.269 | a.46.1 | Methionine synthase domain |
| View | Download | 0.252 | a.60.1 | SAM/Pointed domain |
| View | Download | 0.251 | d.52.3 | Prokaryotic type KH domain (KH-domain type II) |
| View | Download | 0.245 | a.68.1 | Wiscott-Aldrich syndrome protein, WASP, C-terminal domain |
| View | Download | 0.244 | d.58.18 | Regulatory domain in the aminoacid metabolism |
| View | Download | 0.244 | d.56.1 | GroEL-intermediate domain like |
| View | Download | 0.241 | a.60.1 | SAM/Pointed domain |
| View | Download | 0.226 | a.165.1 | Myosin phosphatase inhibitor 17kDa protein, CPI-17 |
| View | Download | 0.219 | a.156.1 | S13-like H2TH domain |
| View | Download | 0.210 | d.58.14 | Ribosomal protein S6 |
| View | Download | 0.202 | a.61.1 | Retroviral matrix proteins |
| View | Download | 0.200 | d.74.4 | Prokaryotic AspRS, insert domain |
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Region A: Residues: [87-675] |
1 11 21 31 41 51
| | | | | |
1 VGKYTVDLSN YSKIELRYYE FLCRVSEVKI WIEAVIEEAL PSEIELCVGD SLRNGVFLAK 60
61 LTQRINPDLT TVIFPAGDKL QFKHTQNINA FFGLVEHVGV PDSFRFELQD LYNKKNIPQV 120
121 FETLHILISM INKKWPGKTP ALTNVSGQIS FTKEEIAACK KAWPRIRDFK SLGTNINTAP 180
181 ASPEEPKEKR SGLIKDFNKF ERPNIPVEEI LITPRKNITD ANCSDFSNTP SPYNEAPKMS 240
241 NLDVVVEKRK FTPIEPSLLG PTPSLEYSPI KNKSLSYYSP TISKYLTYDT EFYTRRSRAR 300
301 EEDLNYYQTF KYSPSHYSPM RRERMTEEQF LEKVVQLQNI CRGVNTRFNL YIQKRLLNLF 360
361 EQDILRFQAC LRGNKFRVLS SMYLPIRRAK IDVPHVEAIQ SRIKGSRIRY KYDKLKFTLS 420
421 RFSCTVELLQ AYCRSKLLKT TVNTKLNDIE ISHYPLTKLQ SYMRASYVRK KVMSLNTKLN 480
481 DERESIMKFS AIIRGNVVRC SEDAILSAVH DVHKENISKL QSLIRGIFTR SCLASIIYSL 540
541 GKENCNIIQL SACIRGNAVR HKVQSLFAPE NNLSETVHDL QGLVRGILV
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| Detection Method: | |
| Confidence: | 149.0 |
| Match: | 1i84S_ |
| Description: | Heavy meromyosin subfragment |
Matching Structure (courtesy of the PDB): |
|
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Region A: Residues: [676-973] |
1 11 21 31 41 51
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1 RYTLDLVDDI VEYNNLALFQ AFSRGALVRE SLDQKSSFYK RNVRSVIMIQ SWIRKSLQRS 60
61 AYLELLDCPN PSLWAVKKFV HLLNGTATIE EVQNQLESCQ ASLDSENMKK ERLLKSIRQQ 120
121 LNINGVLDKF GLLKDKDHEL GISDSTIPKS KYQKYEKLFY MLQVDPSYWK LLYLKEPEFV 180
181 AKNVYMTFGT VNQRMNDRER SYFTRFVCEM LQNAINEAPS IESFLDNRSQ FWQTILQDFL 240
241 RRESPEFFSI IVPVLDYLSD PVVDFESDPY KIYQEIHGFS SPQHCSPVDD ASTKNKFI
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| Detection Method: | |
| Confidence: | 149.0 |
| Match: | 1i84S_ |
| Description: | Heavy meromyosin subfragment |
| Matching Structure (courtesy of the PDB): |
|
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Region A: Residues: [974-1168] |
1 11 21 31 41 51
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1 DNLRCLWHAI EMVAEIYTRK VHTIPVEIRY LCTKIFCYAA DKNIEEIDSL RAISSILVNV 60
61 FVSEYLVNRE YYGYKDSNVQ KNNQKIDILM KSLATVFEIK NFDGFLDPLN QYANEIKPHI 120
121 KDVLYNVLVD PEYEQEGDRL IYLDMVSPSP KLELLTEKVL EISGKFEEYL NEFPEADILH 180
181 DILEKNLDNS SFPRS
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| Detection Method: | |
| Confidence: | 57.0 |
| Match: | 1nf1A_ |
| Description: | GAP related domain of neurofibromin |
Matching Structure (courtesy of the PDB): |
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Region A: Residues: [1169-1249] |
1 11 21 31 41 51
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1 GRVTLELDAS AYRFLVSDDK MRKIYDQVKR AFVYMMQIED VDTNLYDLSI STILPQDEPN 60
61 FANFLEQNPK IRDDPMIQKL K
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| Detection Method: | |
Shown below are all of our de novo (Rosetta) predictions for this domain.
Click here to view only most confident match.
| MCM Score |
SCOP Match |
SCOP Description | ||
| View | Download | 0.566 | d.58.7 | RNA-binding domain, RBD |
| View | Download | 0.564 | a.118.1 | ARM repeat |
| View | Download | 0.574 | a.28.3 | Retrovirus capsid protein C-terminal domain |
| View | Download | 0.633 | d.68.4 | YhbY-like |
| View | Download | 0.587 | d.43.1 | Elongation factor Ts (EF-Ts), dimerisation domain |
| View | Download | 0.523 | a.74.1 | Cyclin-like |
| View | Download | 0.520 | a.64.1 | Saposin |
| View | Download | 0.490 | c.51.1 | Anticodon-binding domain of Class II aaRS |
| View | Download | 0.475 | d.8.1 | Urease, gamma-subunit |
| View | Download | 0.414 | d.68.1 | Translation initiation factor IF3, C-terminal domain |
| View | Download | 0.413 | d.226.1 | GIY-YIG endonuclease |
| View | Download | 0.410 | d.15.1 | Ubiquitin-like |
| View | Download | 0.400 | c.51.1 | Anticodon-binding domain of Class II aaRS |
| View | Download | 0.397 | d.54.1 | Enolase N-terminal domain-like |
| View | Download | 0.391 | b.84.2 | Rudiment single hybrid motif |
| View | Download | 0.390 | b.84.2 | Rudiment single hybrid motif |
| View | Download | 0.375 | c.55.3 | Ribonuclease H-like |
| View | Download | 0.368 | b.84.2 | Rudiment single hybrid motif |
| View | Download | 0.349 | a.77.1 | DEATH domain |
| View | Download | 0.333 | c.47.1 | Thioredoxin-like |
| View | Download | 0.331 | d.58.4 | Dimeric alpha+beta barrel |
| View | Download | 0.328 | a.4.9 | Polynucleotide phosphorylase/guanosine pentaphosphate synthase (PNPase/GPSI), domain 3 |
| View | Download | 0.316 | d.58.44 | Multidrug efflux transporter AcrB pore domain; PN1, PN2, PC1 and PC2 subdomains |
| View | Download | 0.313 | a.74.1 | Cyclin-like |
| View | Download | 0.307 | a.74.1 | Cyclin-like |
| View | Download | 0.295 | d.68.7 | R3H domain |
| View | Download | 0.292 | c.48.1 | TK C-terminal domain-like |
| View | Download | 0.289 | d.16.1 | FAD-linked reductases, C-terminal domain |
| View | Download | 0.288 | c.58.1 | Aminoacid dehydrogenase-like, N-terminal domain |
| View | Download | 0.285 | a.8.1 | Bacterial immunoglobulin/albumin-binding domains |
| View | Download | 0.278 | a.77.1 | DEATH domain |
| View | Download | 0.278 | a.26.1 | 4-helical cytokines |
| View | Download | 0.272 | a.76.1 | Iron-dependent represor protein, dimerization domain |
| View | Download | 0.267 | a.4.5 | "Winged helix" DNA-binding domain |
| View | Download | 0.264 | d.235.1 | Hypothetical protein Yhr087W |
| View | Download | 0.262 | c.47.1 | Thioredoxin-like |
| View | Download | 0.247 | d.15.7 | Immunoglobulin-binding domains |
| View | Download | 0.240 | d.39.1 | Dynein light chain 8 (DLC8) |
| View | Download | 0.233 | a.28.1 | ACP-like |
| View | Download | 0.227 | a.85.1 | Hemocyanin, N-terminal domain |
| View | Download | 0.225 | c.49.1 | Pyruvate kinase, C-terminal domain |
| View | Download | 0.222 | d.58.24 | CheY-binding domain of CheA |
| View | Download | 0.222 | a.56.1 | CO dehydrogenase ISP C-domain like |
| View | Download | 0.222 | a.138.1 | Multiheme cytochromes |
| View | Download | 0.221 | d.15.6 | Superantigen toxins, C-terminal domain |
| View | Download | 0.218 | d.58.18 | Regulatory domain in the aminoacid metabolism |
| View | Download | 0.210 | d.153.1 | N-terminal nucleophile aminohydrolases (Ntn hydrolases) |
| View | Download | 0.204 | a.4.5 | "Winged helix" DNA-binding domain |
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Region A: Residues: [1250-1495] |
1 11 21 31 41 51
| | | | | |
1 PLKYFTLKNV TLKKIHELES TGTFCSSDNK LQNFLNDIAN TIKNPNYAID YVTQEIYITK 60
61 ETLTKISEMN HSLDIELSRL KKHVDHTIKD FQKAKDFSPV HKSKFGNFKN AVKKVQGRER 120
121 SELQGMKFKW NTKQLYERGV LKTIRGEKLA ELTVKVFGSS GPKFPDIIFK ISTSDGSRFG 180
181 IQMIDKRKGP DKRYSDDVDS FSFKDLIKTQ VEPKIETWKL FHSNVVVNNS QLLHLIVSFF 240
241 YKRNAL
|
| Detection Method: | |
Shown below are all of our structure predictions for this domain.
Click here to view only most confident match.
Found no structure predictions for this domain.
| Term | Confidence | Notes |
| actin binding | 4.78749876353566 | bayes_pls_golite062009 |
| GTPase regulator activity | 3.48313315541019 | bayes_pls_golite062009 |
| nucleoside-triphosphatase regulator activity | 3.46216378778416 | bayes_pls_golite062009 |
| cytoskeletal protein binding | 3.44145669357816 | bayes_pls_golite062009 |
| enzyme regulator activity | 2.73117303901364 | bayes_pls_golite062009 |
| calmodulin binding | 2.44376064579262 | bayes_pls_golite062009 |
| binding | 2.21550924222852 | bayes_pls_golite062009 |
| small GTPase regulator activity | 1.52776228366828 | bayes_pls_golite062009 |
| protein binding | 1.37785152807615 | bayes_pls_golite062009 |
| Ras GTPase activator activity | 1.32591250158464 | bayes_pls_golite062009 |
| GTPase inhibitor activity | 1.1177126331255 | bayes_pls_golite062009 |
| Rho GTPase binding | 1.00104187823298 | bayes_pls_golite062009 |
| GTPase activator activity | 0.945543525650563 | bayes_pls_golite062009 |
| small GTPase binding | 0.78616895231719 | bayes_pls_golite062009 |
| GTPase binding | 0.76727022636058 | bayes_pls_golite062009 |
| enzyme activator activity | 0.514378360493585 | bayes_pls_golite062009 |
| enzyme binding | 0.44096806806257 | bayes_pls_golite062009 |
| Ras GTPase binding | 0.245740027562592 | bayes_pls_golite062009 |
| enzyme inhibitor activity | 0.0914865633301911 | bayes_pls_golite062009 |
