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View Structure Prediction Details

Protein: DJP1_YEAST
Organism: Saccharomyces cerevisiae S288c
Length: 432 amino acids
Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16



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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for DJP1_YEAST.

Description E-value Query
Range		 Subject
Range
DJP1_YEAST - DnaJ-like protein 1 OS=Saccharomyces cerevisiae (strain ATCC 204508 / S288c) GN=DJP1 PE=1 SV=1
DJP1 - Cytosolic J-domain-containing protein, required for peroxisomal protein import and involved in perox...
gi|190406219 - gi|190406219|gb|EDV09486.1| conserved hypothetical protein [Saccharomyces cerevisiae RM11-1a]
 5.0E-95 [1..432] [1..432]
DNAJ_RHILO - Chaperone protein dnaJ OS=Rhizobium loti GN=dnaJ PE=3 SV=1
DNAJ_RHILO - Chaperone protein DnaJ OS=Rhizobium loti (strain MAFF303099) GN=dnaJ PE=3 SV=1
 3.0E-87 [3..362] [1..355]
DNAJ_AGRFC - Chaperone protein DnaJ OS=Agrobacterium fabrum (strain C58 / ATCC 33970) GN=dnaJ PE=2 SV=2
gi|25296037, gi|... - pir||AD2591 molecular chaperone, DnaJ family dnaJ [imported] - Agrobacterium tumefaciens (strain C58...
 7.0E-87 [2..362] [1..360]
DNAJ_BRUOV - Chaperone protein dnaJ - Brucella ovis
 2.0E-85 [3..362] [1..355]
DNAJ_RHIME - Chaperone protein DnaJ OS=Rhizobium meliloti (strain 1021) GN=dnaJ PE=3 SV=1
DNAJ_RHIME - Chaperone protein dnaJ OS=Rhizobium meliloti GN=dnaJ PE=3 SV=1
 4.0E-83 [3..362] [1..359]
gi|107103857 - gi|107103857|ref|ZP_01367775.1| hypothetical protein PaerPA_01004928 [Pseudomonas aeruginosa PACS2]
DNAJ_PSEA8 - Chaperone protein DnaJ OS=Pseudomonas aeruginosa (strain LESB58) GN=dnaJ PE=3 SV=1
DNAJ_PSEAE - Chaperone protein dnaJ OS=Pseudomonas aeruginosa GN=dnaJ PE=3 SV=1
DNAJ_PSEAB - Chaperone protein DnaJ OS=Pseudomonas aeruginosa (strain UCBPP-PA14) GN=dnaJ PE=3 SV=1
DNAJ_PSEAE - Chaperone protein DnaJ OS=Pseudomonas aeruginosa (strain ATCC 15692 / PAO1 / 1C / PRS 101 / LMG 1222...
gi|194549490, gi... - gi|84317360|ref|ZP_00965808.1| COG0484: DnaJ-class molecular chaperone with C-terminal Zn finger dom...
gi|126197717, gi... - gi|84323584|ref|ZP_00971653.1| COG0484: DnaJ-class molecular chaperone with C-terminal Zn finger dom...
 5.0E-82 [2..358] [1..353]
gi|89106899, gi|... - gi|89106899|ref|AP_000679.1| chaperone Hsp40, co-chaperone with DnaK [Escherichia coli str. K-12 sub...
DNAJ_ECODH - Chaperone protein DnaJ OS=Escherichia coli (strain K12 / DH10B) GN=dnaJ PE=3 SV=1
DNAJ_ECOLI - Chaperone protein dnaJ (Heat shock protein J) (HSP40) - Escherichia coli
EG10240 - chaperone Hsp40, DnaK co-chaperone / DnaK co-chaperone HSP40; DNA-binding protein; stress-related DN...
EG10240 - chaperone Hsp40, DnaK co-chaperone / DnaK co-chaperone HSP40; DNA-binding protein; stress-related DN...
 2.0E-81 [2..357] [1..347]
DNAJ_BRUSU - Chaperone protein DnaJ OS=Brucella suis biovar 1 (strain 1330) GN=dnaJ PE=3 SV=1
DNAJ_BRUME - Chaperone protein DnaJ OS=Brucella melitensis biotype 1 (strain 16M / ATCC 23456 / NCTC 10094) GN=dn...
DNAJ_BRUMB - Chaperone protein DnaJ OS=Brucella melitensis biotype 2 (strain ATCC 23457) GN=dnaJ PE=3 SV=1
gi|225618155, gi... - gi|225626498|ref|ZP_03784537.1| chaperone protein DnaJ [Brucella ceti str. Cudo], gi|225618155|gb|EE...
gi|254705131 - gi|254705131|ref|ZP_05166959.1| chaperone protein DnaJ [Brucella suis bv. 3 str. 686]
DNAJ_BRUSU - Chaperone protein dnaJ OS=Brucella suis GN=dnaJ PE=3 SV=1
gi|254700759 - gi|254700759|ref|ZP_05162587.1| chaperone protein DnaJ [Brucella suis bv. 5 str. 513]
gi|254709104 - gi|254709104|ref|ZP_05170915.1| chaperone protein DnaJ [Brucella pinnipedialis B2/94]
DNAJ_BRUME - Chaperone protein dnaJ OS=Brucella melitensis GN=dnaJ PE=3 SV=1
gi|254707354 - gi|254707354|ref|ZP_05169182.1| chaperone protein DnaJ [Brucella pinnipedialis M163/99/10]
gi|254718169 - gi|254718169|ref|ZP_05179980.1| chaperone protein DnaJ [Brucella sp. 83/13]
DNAJ_BRUSI - Chaperone protein DnaJ OS=Brucella suis (strain ATCC 23445 / NCTC 10510) GN=dnaJ PE=3 SV=1
DNAJ_BRUC2 - Chaperone protein DnaJ OS=Brucella canis (strain ATCC 23365 / NCTC 10854) GN=dnaJ PE=3 SV=1
 2.0E-81 [3..362] [1..357]
DNAJ_RALSO - Chaperone protein dnaJ OS=Ralstonia solanacearum GN=dnaJ PE=3 SV=1
DNAJ_RALSO - Chaperone protein DnaJ OS=Ralstonia solanacearum (strain GMI1000) GN=dnaJ PE=3 SV=1
 3.0E-81 [2..357] [1..355]

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Predicted Domain #1
Region A:
Residues: [1-117] 
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MVVDTEYYDL LGVSTTASSI EIKKAYRKKS IQEHPDKNPN DPTATERFQA ISEAYQVLGD  60
   61 DDLRAKYDKY GRKEAIPQGG FEDAAEQFSV IFGGDAFASY IGELMLLKNL QKTEELN

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 143.70927
Match: 1xbl__
Description: DnaJ chaperone, N-terminal (J) domain
Matching Structure (courtesy of the PDB):

Predicted functions:

Term Confidence Notes
unfolded protein binding 3.04403163860617 bayes_pls_golite062009
binding 2.4835091517649 bayes_pls_golite062009
heat shock protein binding 2.17994194200939 bayes_pls_golite062009
protein binding 1.81676109739118 bayes_pls_golite062009
chaperone binding 1.61155546076854 bayes_pls_golite062009
Hsp70 protein binding 0.541755903922701 bayes_pls_golite062009
nucleic acid binding 0.423488346839872 bayes_pls_golite062009
transcription regulator activity 0.146399219759372 bayes_pls_golite062009
catalytic activity 0.106988907594358 bayes_pls_golite062009
DNA binding 0.10307408349439 bayes_pls_golite062009

Predicted Domain #2
Region A:
Residues: [118-197] 
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 AEDEAEKEKE NVETMEESPA DGKTNGTTNA VDAALGNTNE KDDKNKARTT SGNLTVHDGN  60
   61 KKNEQVGAEA KKKKTKLEQF

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 17.69897
Match: 1exkA_
Description: Cysteine-rich domain of the chaperone protein DnaJ.
Matching Structure (courtesy of the PDB):

Predicted functions:

Term Confidence Notes
binding 2.58201259799527 bayes_pls_golite062009
unfolded protein binding 2.04158808514315 bayes_pls_golite062009
protein binding 1.7866515791227 bayes_pls_golite062009
protein disulfide isomerase activity 0.290861970307477 bayes_pls_golite062009
intramolecular oxidoreductase activity, transposing S-S bonds 0.290861970307477 bayes_pls_golite062009
catalytic activity 0.276917867171685 bayes_pls_golite062009
intramolecular oxidoreductase activity, interconverting keto- and enol-groups 0.0964866497718595 bayes_pls_golite062009

Predicted Domain #3
Region A:
Residues: [198-325] 
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 EEEQEVEKQK RVDQLSKTLI ERLSILTESV YDDACKDSFK KKFEEEANLL KMESFGLDIL  60
   61 HTIGDVYYEK AEIFLASQNL FGMGGIFHSM KAKGGVFMDT LRTVSAAIDA QNTMKELEKM 120
  121 KEASTNNE

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 15.045757
Match: 1c3gA_
Description: Heat shock protein 40 Sis1
Matching Structure (courtesy of the PDB):

Predicted Domain #4
Region A:
Residues: [326-432] 
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 PLFDKDGNEQ IKPTTEELAQ QEQLLMGKVL SAAWHGSKYE ITSTLRGVCK KVLEDDSVSK  60
   61 KTLIRRAEAM KLLGEVFKKT FRTKVEQEEA QIFEELVAEA TKKKRHT

[Run NCBI BLAST on this sequence.]

Detection Method: MSA

Shown below is our most confident prediction for this domain.
Click here to view all matches.

    MCM
Score		 GO
Score		 GO
Term		 SCOP
Match		 SCOP Description
View Download 0.978 0.001 cytosol a.24.17 Group V grass pollen allergen

YRC Informatics Platform - Version 3.0
Created and Maintained by: Michael Riffle