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View Structure Prediction Details

Protein: BRE5_YEAST
Organism: Saccharomyces cerevisiae S288c
Length: 515 amino acids
Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16



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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for BRE5_YEAST.

Description E-value Query
Range		 Subject
Range
BRE5 - Ubiquitin protease cofactor, forms deubiquitination complex with Ubp3p that coregulates anterograde ...
BRE5_YEAST - UBP3-associated protein BRE5 OS=Saccharomyces cerevisiae (strain ATCC 204508 / S288c) GN=BRE5 PE=1 S...
 9.0E-56 [1..515] [1..515]
gi|8163674 - gi|8163674|gb|AAF73795.1|AF154026_1 surface protein PspC [Streptococcus pneumoniae]
 2.0E-45 [38..421] [75..486]
gi|25509405, gi|... - gi|8163644|gb|AAF73779.1| surface protein PspC [Streptococcus pneumoniae], pir||H98120 choline bindi...
gi|15459699, gi|... - gi|15904036|ref|NP_359586.1| choline binding protein A [Streptococcus pneumoniae R6], gi|15459699|gb...
gi|116515359, gi... - gi|8163644|gb|AAF73779.1|AF154012_1 surface protein PspC [Streptococcus pneumoniae], gi|116515359|re...
 2.0E-41 [36..421] [74..495]
ZAN_MOUSE - Zonadhesin OS=Mus musculus GN=Zan PE=1 SV=1
 2.0E-41 [74..508] [466..927]
gi|16554449, gi|... - gi|16554449|ref|NP_003377.1| zonadhesin isoform 3 [Homo sapiens], gi|12667414|gb|AAK01433.1|AF332977...
 1.0E-39 [74..510] [460..928]
IGA1A_STRPN - Immunoglobulin A1 protease OS=Streptococcus pneumoniae GN=iga PE=3 SV=1
IGA1A_STRPN - Immunoglobulin A1 protease OS=Streptococcus pneumoniae serotype 4 (strain ATCC BAA-334 / TIGR4) GN=i...
 1.0E-39 [25..448] [313..738]

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Predicted Domain #1
Region A:
Residues: [1-149] 
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MGVTVQDICF AFLQNYYERM RTDPSKLAYF YASTAELTHT NYQSKSTNEK DDVLPTVKVT  60
   61 GRENINKFFS RNDAKVRSLK LKLDTIDFQY TGHLHKSILI MATGEMFWTG TPVYKFCQTF 120
  121 ILLPSSNGST FDITNDIIRF ISNSFKPYV

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 9.522879
Match: 1gy7A_
Description: Nuclear transport factor-2 (NTF2)
Matching Structure (courtesy of the PDB):

Predicted functions:

Term Confidence Notes
binding 1.88422211140837 bayes_pls_golite062009
protein binding 1.34243535208605 bayes_pls_golite062009
nucleic acid binding 1.28328198842973 bayes_pls_golite062009
protein serine/threonine kinase activity 0.797931524291551 bayes_pls_golite062009
protein kinase activity 0.622060011038738 bayes_pls_golite062009
phosphotransferase activity, alcohol group as acceptor 0.528127152698506 bayes_pls_golite062009
kinase activity 0.401688821547236 bayes_pls_golite062009
transferase activity, transferring phosphorus-containing groups 0.16347882814309 bayes_pls_golite062009
structural molecule activity 0.123366004333113 bayes_pls_golite062009

Predicted Domain #2
Region A:
Residues: [150-515] 
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 LTDASLSQSN EENSVSAVEE DKIRHESGVE KEKEKEKSPE ISKPKAKKET VKDTTAPTES  60
   61 STQEKPIVDH SQPRAIPVTK ESKIHTETVP SSTKGNHKQD EVSTEELGNV TKLNEKSHKA 120
  121 EKKAAPIKTK EGSVEAINAV NNSSLPNGKE VSDEKPVPGG VKEAETEIKP IEPQVSDAKE 180
  181 SGNNASTPSS SPEPVANPPK MTWASKLMNE NSDRISKNNT TVEYIRPETL PKKPTERKFE 240
  241 MGNRRDNASA NSKNKKKPVF STVNKDGFYP IYIRGTNGLR EEKLRSALEK EFGKVMRITA 300
  301 ADNFAVVDFE TQKSQIDALE KKKKSIDGIE VCLERKTVKK PTSNNPPGIF TNGTRSHRKQ 360
  361 PLKRKD

[Run NCBI BLAST on this sequence.]

Detection Method: ORFEUS
Confidence: 14.63
Match: 1m2vB
Description: Sec24
Matching Structure (courtesy of the PDB):
YRC Informatics Platform - Version 3.0
Created and Maintained by: Michael Riffle