YRC Public Data Repository - Protein Structure Prediction

Protein:	gi\|31076070
Organism:	Lactobacillus johnsonii
Length:	412 amino acids
Reference:	Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16

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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for gi|31076070.

Description	E-value	Query Range	Subject Range
gi\|116097955, gi... - gi\|23024352\|ref\|ZP_00063567.1\| COG0520: Selenocysteine lyase [Leuconostoc mesenteroides subsp. mesen...	336.0	[0..9]	[410..4]
gi\|86605110, gi\|... - gi\|86605110\|ref\|YP_473873.1\| SufS family cysteine desulfurase [Synechococcus sp. JA-3-3Ab], gi\|86553... gi\|86605110 - gi\|86605110\|ref\|YP_473873.1\| cysteine desulfurase, SufS family [Cyanobacteria bacterium Yellowstone ...	330.0	[0..9]	[410..25]
gi\|90822047, gi\|... - gi\|90962853\|ref\|YP_536768.1\| putative aminotransferase [Lactobacillus salivarius UCC118], gi\|9082204...	325.0	[0..1]	[408..2]
gi\|89200187, gi\|... - gi\|89200187\|ref\|ZP_01178942.1\| Cysteine desulphurases, SufS [Bacillus cereus subsp. cytotoxis NVH 39...	323.0	[0..4]	[408..1]
gi\|110168810, gi... - gi\|71676267\|ref\|ZP_00674009.1\| Cysteine desulphurases, SufS [Trichodesmium erythraeum IMS101], gi\|71...	322.0	[0..7]	[411..11]
gi\|86557988, gi\|... - gi\|86609446\|ref\|YP_478208.1\| SufS family cysteine desulfurase [Synechococcus sp. JA-2-3B'a(2-13)], g... gi\|86557988, gi\|... - gi\|86609446\|ref\|YP_478208.1\| cysteine desulfurase, SufS family [Cyanobacteria bacterium Yellowstone ...	322.0	[0..7]	[408..19]
gi\|76588976, gi\|... - gi\|76795662\|ref\|ZP_00778034.1\| Cysteine desulphurases, SufS [Thermoanaerobacter ethanolicus ATCC 332... gi\|241904453, gi... - gi\|241904453\|ref\|ZP_04789148.1\| cysteine desulfurase, SufS subfamily [Thermoanaerobacter brockii sub...	321.0	[0..1]	[409..1]
gi\|242231067, gi... - gi\|242257411\|ref\|ZP_04802277.1\| cysteine desulfurase, SufS subfamily [Thermoanaerobacter sp. X513], ... gi\|167040940, gi... - gi\|167040940\|ref\|YP_001663925.1\| SufS subfamily cysteine desulfurase [Thermoanaerobacter sp. X514], ...	321.0	[0..1]	[409..1]
CSD_BACSU - Probable cysteine desulfurase OS=Bacillus subtilis GN=csd PE=3 SV=1 gi\|221324740 - gi\|221324740\|ref\|ZP_03606034.1\| cysteine desulfurase [Bacillus subtilis subsp. subtilis str. SMY] gi\|221315541 - gi\|221315541\|ref\|ZP_03597346.1\| cysteine desulfurase [Bacillus subtilis subsp. subtilis str. NCIB 36... gi\|221320456 - gi\|221320456\|ref\|ZP_03601750.1\| cysteine desulfurase [Bacillus subtilis subsp. subtilis str. JH642] SUFS_BACSU - Cysteine desulfurase SufS OS=Bacillus subtilis (strain 168) GN=sufS PE=1 SV=1	320.0	[0..4]	[408..1]
gi\|218900136, gi... - gi\|218900136\|ref\|YP_002448547.1\| cysteine desulfurase SufS [Bacillus cereus G9842], gi\|218542809\|gb\|... gi\|228910821, gi... - gi\|228910821\|ref\|ZP_04074630.1\| cysteine desulfurase [Bacillus thuringiensis IBL 200], gi\|228848772\|... gi\|228856171, gi... - gi\|228903486\|ref\|ZP_04067611.1\| cysteine desulfurase [Bacillus thuringiensis IBL 4222], gi\|228856171... gi\|228961227, gi... - gi\|228961227\|ref\|ZP_04122847.1\| cysteine desulfurase [Bacillus thuringiensis serovar pakistani str. ... gi\|218233850, gi... - gi\|218233850\|ref\|YP_002369783.1\| cysteine desulfurase SufS [Bacillus cereus B4264], gi\|218161807\|gb\|... gi\|228817483, gi... - gi\|228942149\|ref\|ZP_04104689.1\| cysteine desulfurase [Bacillus thuringiensis serovar berliner ATCC 1... gi\|228784599, gi... - gi\|228975078\|ref\|ZP_04135637.1\| cysteine desulfurase [Bacillus thuringiensis serovar thuringiensis s... gi\|228968099, gi... - gi\|228968099\|ref\|ZP_04129104.1\| cysteine desulfurase [Bacillus thuringiensis serovar sotto str. T040... gi\|229032620, gi... - gi\|229032620\|ref\|ZP_04188584.1\| cysteine desulfurase [Bacillus cereus AH1271], gi\|228728705\|gb\|EEL79... gi\|228981718, gi... - gi\|228981718\|ref\|ZP_04142013.1\| cysteine desulfurase [Bacillus thuringiensis Bt407], gi\|228777830\|gb... gi\|229112426, gi... - gi\|229112426\|ref\|ZP_04241964.1\| cysteine desulfurase [Bacillus cereus Rock1-15], gi\|228671074\|gb\|EEL... gi\|229049673, gi... - gi\|229049673\|ref\|ZP_04194230.1\| cysteine desulfurase [Bacillus cereus AH676], gi\|228722586\|gb\|EEL739... gi\|74491798, gi\|... - gi\|75760714\|ref\|ZP_00740738.1\| Cysteine desulfurase / Selenocysteine lyase [Bacillus thuringiensis ... gi\|228630272, gi... - gi\|229153173\|ref\|ZP_04281352.1\| cysteine desulfurase [Bacillus cereus m1550], gi\|228630272\|gb\|EEK869... gi\|30023021, gi\|... - gi\|30023021\|ref\|NP_834652.1\| cysteine desulfhydrase [Bacillus cereus ATCC 14579], gi\|29898581\|gb\|AAP... gi\|229130239, gi... - gi\|229130239\|ref\|ZP_04259198.1\| cysteine desulfurase [Bacillus cereus BDRD-Cer4], gi\|228653172\|gb\|EE... gi\|228619580, gi... - gi\|229163959\|ref\|ZP_04291899.1\| cysteine desulfurase [Bacillus cereus R309803], gi\|228619580\|gb\|EEK7...	320.0	[0..4]	[408..1]

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Predicted Domain #1

Region A:
Residues: [1-412]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MAKLNTEKIK QDFPIFNQKI NDETLVYLDN AATSQIPKFV EEKVRDFNEK ERANVHRGVH  60
   61 ALGLRATNQY ESSRQKVANF IGANNAKEVI FTSGCTDSLN LVAASFGEQN IQAGDEILVS 120
  121 IMEHHSNLLP WQQLAKRKQA KLNFIEINSD GLLDIKNLKS KINSKTKIVA LTHVSNVLGT 180
  181 INPIKELTDL AHEKGAIVVV DGAQAVGHFP IDVAELNVDF YAFSGHKMFA PTGIGVLYGK 240
  241 KDLLDKMQPY RLGGEMIANV TREGATWAEV PYKFEAGTPN IAGAIGLGAA IDYLQSLDFE 300
  301 LIQKHEQELT SYALEKLKNV SGLTIYGPQK SNGRIGVISF NLKNIHPHDL ATALDLNGIE 360
  361 VRAGHHCAQP LMASLNTEST VRASLSIYNT KDDIDKLVSS LHEAKEFFSE FR

[Run NCBI BLAST on this sequence.]

Detection Method:	PSI-BLAST
Confidence:	81.522879
Match:	1t3iA
Description:	Structure of slr0077/SufS, the Essential Cysteine Desulfurase from Synechocystis PCC 6803
Matching Structure (courtesy of the PDB):

Predicted functions:

Term	Confidence	Notes
glycine dehydrogenase (decarboxylating) activity	3.40354781002256	bayes_pls_golite062009
oxidoreductase activity, acting on the CH-NH2 group of donors, disulfide as acceptor	3.40354781002256	bayes_pls_golite062009
transferase activity	2.59075614411581	bayes_pls_golite062009
catalytic activity	2.29878871754893	bayes_pls_golite062009
L-aspartate:2-oxoglutarate aminotransferase activity	1.62166853560902	bayes_pls_golite062009
cysteine desulfurase activity	1.30923778688541	bayes_pls_golite062009
transferase activity, transferring nitrogenous groups	1.28316822767388	bayes_pls_golite062009
transaminase activity	1.24990480711889	bayes_pls_golite062009
carbon-sulfur lyase activity	0.698312655247044	bayes_pls_golite062009
5-aminolevulinate synthase activity	0.523223426448441	bayes_pls_golite062009
cystathionine gamma-lyase activity	0.505859361763689	bayes_pls_golite062009
transferase activity, transferring acyl groups	0.50269055590758	bayes_pls_golite062009
binding	0.49769115245722	bayes_pls_golite062009
cystathionine beta-lyase activity	0.27933426619091	bayes_pls_golite062009
glycine hydroxymethyltransferase activity	0.271623203801431	bayes_pls_golite062009
O-phospho-L-serine:2-oxoglutarate aminotransferase activity	0.234399054481664	bayes_pls_golite062009
nucleic acid binding	0.186646089509162	bayes_pls_golite062009
vitamin B6 binding	0.16957228630576	bayes_pls_golite062009
pyridoxal phosphate binding	0.16957228630576	bayes_pls_golite062009
sulfurtransferase activity	0.0450490929307473	bayes_pls_golite062009
DNA binding	0.0281750086102144	bayes_pls_golite062009

TMHMM	2.0c	PSIPRED	v2.61
SignalP	3.0	COILS	1999
DISOPRED	v0.1	NCBI nr	06/2007
PSI-BLAST	2.2.18	FFAS	ffas03
PDB	06/2007	Pfam	22
HMMER	2.3.2

View Structure Prediction Details

Top Sequence Alignment Hits

Predicted functions: