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View Structure Prediction Details

Protein: puf-8
Organism: Caenorhabditis elegans
Length: 535 amino acids
Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16



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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for puf-8.

Description E-value Query
Range
Subject
Range
gi|109000900 - gi|109000900|ref|XP_001096411.1| PREDICTED: similar to pumilio 1 isoform 2 isoform 2 [Macaca mulatta...
467.0 [0..23] [521..563]

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Predicted Domain #1
Region A:
Residues: [1-152]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MSRPISIGNT CTFDPSASPI ESLGRSIGAQ KIVDSVCGSP IRSYGRHIST NPKNERLPDT  60
   61 PEFQFATYMH QGGKVIGQNT LHMFGTPPSC YCAQENIPIS SNVGHVLSTI NNNYMNHQYN 120
  121 GSNMFSNQMT QMLQAQAYND LQMHQAHSQS IR

[Run NCBI BLAST on this sequence.]

Detection Method: MSA

Shown below is our most confident prediction for this domain.
Click here to view all matches.

Found no confident structure predictions for this domain.

Predicted Domain #2
Region A:
Residues: [153-535]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 VPVQPSATGI FSNPYREPTT TDDLLTRYRA NPAMMKNLKL SDIRGALLKF AKDQVGSRFI  60
   61 QQELASSKDR FEKDSIFDEV VSNADELVDD IFGNYVVQKF FEYGEERHWA RLVDAIIDRV 120
  121 PEYAFQMYAC RVLQKALEKI NEPLQIKILS QIRHVIHRCM KDQNGNHVVQ KAIEKVSPQY 180
  181 VQFIVDTLLE SSNTIYEMSV DPYGCRVVQR CLEHCSPSQT KPVIGQIHKR FDEIANNQYG 240
  241 NYVVQHVIEH GSEEDRMVIV TRVSNNLFEF ATHKYSSNVI EKCLEQGAVY HKSMIVGAAC 300
  301 HHQEGSVPIV VQMMKDQYAN YVVQKMFDQV TSEQRRELIL TVRPHIPVLR QFPHGKHILA 360
  361 KLEKYFQKPA VMSYPYQDMQ GSH

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 118.0
Match: 1ib2A
Description: Pumilio 1
Matching Structure (courtesy of the PDB):

Predicted functions:

Term Confidence Notes
binding 1.72717267135753 bayes_pls_golite062009
protein binding 1.01840651819417 bayes_pls_golite062009
nucleic acid binding 0.726577126409925 bayes_pls_golite062009
transcription regulator activity 0.198921736439162 bayes_pls_golite062009
translation regulator activity 0.1178495560226 bayes_pls_golite062009
translation factor activity, nucleic acid binding 0.10960901634151 bayes_pls_golite062009
catalytic activity 0.0114279309788371 bayes_pls_golite062009

YRC Informatics Platform - Version 3.0
Created and Maintained by: Michael Riffle