YRC Logo
PROTEIN SEARCH:
Descriptions Names[Advanced Search]

View Structure Prediction Details

Protein: FSH3_YEAST
Organism: Saccharomyces cerevisiae S288c
Length: 266 amino acids
Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16



[What does the above image mean?]


[Show Ginzu Version Information]


Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for FSH3_YEAST.

Description E-value Query
Range		 Subject
Range
FSH3 - Putative serine hydrolase; likely target of Cyc8p-Tup1p-Rfx1p transcriptional regulation; sequence i...
FSH3_YEAST - Family of serine hydrolases 3 OS=Saccharomyces cerevisiae (strain ATCC 204508 / S288c) GN=FSH3 PE=2 ...
 5.0E-80 [1..266] [1..266]
gi|3721988 - gi|3721988|gb|AAC63431.1| calcium-independent phospholipase A2 isoform 1 [Oryctolagus cuniculus]
 1.0E-50 [2..230] [6..216]
gi|123996083, gi... - gi|123996083|gb|ABM85643.1| lysophospholipase I [synthetic construct], gi|123981248|gb|ABM82453.1| l...
LYPLA1 - lysophospholipase I
 4.0E-50 [2..230] [17..227]
LYPA1_RABIT - Acyl-protein thioesterase 1 OS=Oryctolagus cuniculus GN=LYPLA1 PE=1 SV=1
LYPA1_MOUSE - Acyl-protein thioesterase 1 OS=Mus musculus GN=Lypla1 PE=1 SV=1
 5.0E-50 [2..230] [17..227]
dfr1 - dihydrofolate reductase Dfr1
DYR_SCHPO - Dihydrofolate reductase OS=Schizosaccharomyces pombe (strain 972 / ATCC 24843) GN=dfr1 PE=2 SV=2
 4.0E-49 [1..238] [1..232]
gi|23306356, gi|... - gi|79328183|ref|NP_001031909.1| phospholipase/carboxylesterase family protein [Arabidopsis thaliana]...
 5.0E-49 [3..233] [32..252]
gi|7507776 - gi|7507776|pir||T16867 probable cytochrome P450 T13C5.1 [similarity] - Caenorhabditis elegans
 5.0E-49 [1..238] [1..232]
LYPA1_RAT - Acyl-protein thioesterase 1 OS=Rattus norvegicus GN=Lypla1 PE=1 SV=1
 7.0E-49 [2..230] [17..227]

Back

Predicted Domain #1
Region A:
Residues: [1-266] 
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MSEKKKVLML HGFVQSDKIF SAKTGGLRKN LKKLGYDLYY PCAPHSIDKK ALFQSESEKG  60
   61 RDAAKEFNTS ATSDEVYGWF FRNPESFNSF QIDQKVFNYL RNYVLENGPF DGVIGFSQGA 120
  121 GLGGYLVTDF NRILNLTDEQ QPALKFFISF SGFKLEDQSY QKEYHRIIQV PSLHVRGELD 180
  181 EVVAESRIMA LYESWPDNKR TLLVHPGAHF VPNSKPFVSQ VCNWIQGITS KEGQEHNAQP 240
  241 EVDRKQFDKP QLEDDLLDMI DSLGKL

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 50.30103
Match: 1fj2A_
Description: Acyl protein thioesterase 1
Matching Structure (courtesy of the PDB):

Predicted functions:

Term Confidence Notes
catalytic activity 1.39629727416851 bayes_pls_golite062009
binding 0.978846093152455 bayes_pls_golite062009
hydrolase activity, acting on ester bonds 0.603999106175838 bayes_pls_golite062009
structural molecule activity 0.165872846726831 bayes_pls_golite062009
carboxylesterase activity 0.0264147222103929 bayes_pls_golite062009
YRC Informatics Platform - Version 3.0
Created and Maintained by: Michael Riffle