YRC Public Data Repository - Protein Structure Prediction

Protein:	HIS4_RALSO
Organism:	Ralstonia solanacearum GMI1000
Length:	247 amino acids
Reference:	Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16

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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for HIS4_RALSO.

Description	E-value	Query Range	Subject Range
gi\|83747543, gi\|... - gi\|83747543\|ref\|ZP_00944581.1\| Phosphoribosylformimino-5-aminoimidazole carboxamide ribotide isomera...	220.0	[0..1]	[247..1]
HIS4_BURCA - 1-(5-phosphoribosyl)-5-[(5-phosphoribosylamino)methylideneamino] imidazole-4-carboxamide isomerase O... HIS4_BURCC - 1-(5-phosphoribosyl)-5-[(5-phosphoribosylamino)methylideneamino] imidazole-4-carboxamide isomerase O... gi\|158343902, gi... - gi\|158343982\|gb\|ABW35777.1\| phosphoribosylformimino-5-aminoimidazole carboxamide ribotide isomerase ... gi\|124871300, gi... - gi\|254246524\|ref\|ZP_04939845.1\| Phosphoribosylformimino-5-aminoimidazole carboxamide ribotide isomer... HIS4_BURCJ - 1-(5-phosphoribosyl)-5-[(5-phosphoribosylamino)methylideneamino] imidazole-4-carboxamide isomerase O...	219.0	[0..1]	[243..1]
HIS4_BURCH - 1-(5-phosphoribosyl)-5-[(5-phosphoribosylamino)methylideneamino] imidazole-4-carboxamide isomerase O...	218.0	[0..1]	[243..1]
HIS4_BURVG - 1-(5-phosphoribosyl)-5-[(5-phosphoribosylamino)methylideneamino] imidazole-4-carboxamide isomerase O... gi\|229424439 - gi\|229424439\|gb\|ACQ65656.1\| phosphoribosylformimino-5-aminoimidazole carboxamide ribotide isomerase ...	218.0	[0..1]	[243..1]
HIS4_BURL3 - 1-(5-phosphoribosyl)-5-[(5-phosphoribosylamino)methylideneamino] imidazole-4-carboxamide isomerase O... HIS4_BURS3 - 1-(5-phosphoribosyl)-5-[(5-phosphoribosylamino)methylideneamino] imidazole-4-carboxamide isomerase O...	216.0	[0..1]	[243..1]
gi\|148026335, gi... - gi\|254357271\|ref\|ZP_04973545.1\| phosphoribosylformimino-5-aminoimidazole carboxamide ribotide isomer... gi\|147752188, gi... - gi\|254206646\|ref\|ZP_04912997.1\| phosphoribosylformimino-5-aminoimidazole carboxamide ribotide isomer... gi\|147747198, gi... - gi\|254201304\|ref\|ZP_04907668.1\| phosphoribosylformimino-5-aminoimidazole carboxamide ribotide isomer... gi\|134245382, gi... - gi\|134283187\|ref\|ZP_01769888.1\| phosphoribosylformimino-5-aminoimidazole carboxamide ribotide isomer... gi\|167740452 - gi\|167740452\|ref\|ZP_02413226.1\| 1-(5-phosphoribosyl)-5-[(5-phosphoribosylamino)methylideneamino] imi... gi\|237505639, gi... - gi\|237814061\|ref\|YP_002898512.1\| 1-(5-phosphoribosyl)-5-[(5-phosphoribosylamino)methylideneamino]imi... gi\|167721482 - gi\|167721482\|ref\|ZP_02404718.1\| 1-(5-phosphoribosyl)-5-[(5-phosphoribosylamino)methylideneamino] imi... gi\|238522542, gi... - gi\|238562498\|ref\|ZP_00440365.2\| 1-(5-phosphoribosyl)-5-[(5-phosphoribosylamino)methylideneamino]imid... gi\|167826063 - gi\|167826063\|ref\|ZP_02457534.1\| 1-(5-phosphoribosyl)-5-[(5-phosphoribosylamino)methylideneamino] imi... gi\|167817665 - gi\|167817665\|ref\|ZP_02449345.1\| 1-(5-phosphoribosyl)-5-[(5-phosphoribosylamino)methylideneamino] imi... gi\|242316828, gi... - gi\|242316828\|ref\|ZP_04815844.1\| 1-(5-phosphoribosyl)-5-[(5-phosphoribosylamino)methylideneamino]imid... gi\|167001599, gi... - gi\|243062608\|gb\|EES44794.1\| 1-(5-phosphoribosyl)-5-[(5-phosphoribosylamino)methylideneamino]imidazol... gi\|161372216, gi... - gi\|254259441\|ref\|ZP_04950495.1\| 1-(5-phosphoribosyl)-5-[(5-phosphoribosylamino)methylideneamino]imid... gi\|157810464, gi... - gi\|254300657\|ref\|ZP_04968102.1\| phosphoribosylformimino-5-aminoimidazole carboxamide ribotide isomer... HIS4_BURPS - 1-(5-phosphoribosyl)-5-[(5-phosphoribosylamino)methylideneamino] imidazole-4-carboxamide isomerase O... gi\|194514281, gi... - gi\|254198588\|ref\|ZP_04905009.1\| phosphoribosylformimino-5-aminoimidazole carboxamide ribotide isomer... HIS4_BURMA - 1-(5-phosphoribosyl)-5-[(5-phosphoribosylamino)methylideneamino] imidazole-4-carboxamide isomerase O... HIS4_BURM9 - 1-(5-phosphoribosyl)-5-[(5-phosphoribosylamino)methylideneamino] imidazole-4-carboxamide isomerase O... HIS4_BURMS - 1-(5-phosphoribosyl)-5-[(5-phosphoribosylamino)methylideneamino] imidazole-4-carboxamide isomerase O... gi\|217424799, gi... - gi\|217424799\|ref\|ZP_03456296.1\| 1-(5-phosphoribosyl)-5-[(5-phosphoribosylamino)methylideneamino]imid... HIS4_BURM7 - 1-(5-phosphoribosyl)-5-[(5-phosphoribosylamino)methylideneamino] imidazole-4-carboxamide isomerase O... gi\|194316874, gi... - gi\|254174984\|ref\|ZP_04881645.1\| phosphoribosylformimino-5-aminoimidazole carboxamide ribotide isomer... HIS4_BURP6 - 1-(5-phosphoribosyl)-5-[(5-phosphoribosylamino)methylideneamino] imidazole-4-carboxamide isomerase O... gi\|167920751 - gi\|167920751\|ref\|ZP_02507842.1\| 1-(5-phosphoribosyl)-5-[(5-phosphoribosylamino)methylideneamino] imi... gi\|157938060, gi... - gi\|254190384\|ref\|ZP_04896892.1\| phosphoribosylformimino-5-aminoimidazole carboxamide ribotide isomer... HIS4_BURP0 - 1-(5-phosphoribosyl)-5-[(5-phosphoribosylamino)methylideneamino] imidazole-4-carboxamide isomerase O... gi\|184210960, gi... - gi\|254180421\|ref\|ZP_04887019.1\| phosphoribosylformimino-5-aminoimidazole carboxamide ribotide isomer... gi\|167896145 - gi\|167896145\|ref\|ZP_02483547.1\| 1-(5-phosphoribosyl)-5-[(5-phosphoribosylamino)methylideneamino] imi... gi\|167847569 - gi\|167847569\|ref\|ZP_02473077.1\| 1-(5-phosphoribosyl)-5-[(5-phosphoribosylamino)methylideneamino] imi... gi\|167912792 - gi\|167912792\|ref\|ZP_02499883.1\| 1-(5-phosphoribosyl)-5-[(5-phosphoribosylamino)methylideneamino] imi... gi\|167904529 - gi\|167904529\|ref\|ZP_02491734.1\| 1-(5-phosphoribosyl)-5-[(5-phosphoribosylamino)methylideneamino] imi... HIS4_BURMA - 1-(5-phosphoribosyl)-5-[(5-phosphoribosylamino)methylideneamino] imidazole-4-carboxamide isomerase O... HIS4_BURPS - 1-(5-phosphoribosyl)-5-[(5-phosphoribosylamino)methylideneamino] imidazole-4-carboxamide isomerase O... HIS4_BURP1 - 1-(5-phosphoribosyl)-5-[(5-phosphoribosylamino)methylideneamino] imidazole-4-carboxamide isomerase O...	214.0	[0..1]	[243..1]
HIS4_CUPPJ - 1-(5-phosphoribosyl)-5-[(5-phosphoribosylamino)methylideneamino] imidazole-4-carboxamide isomerase O...	214.0	[0..1]	[243..1]
HIS4_BURTA - 1-(5-phosphoribosyl)-5-[(5-phosphoribosylamino)methylideneamino] imidazole-4-carboxamide isomerase O... gi\|167838121 - gi\|167838121\|ref\|ZP_02464980.1\| 1-(5-phosphoribosyl)-5-[(5-phosphoribosylamino)methylideneamino] imi... gi\|167620650 - gi\|167620650\|ref\|ZP_02389281.1\| 1-(5-phosphoribosyl)-5-[(5-phosphoribosylamino)methylideneamino] imi... gi\|167582535 - gi\|167582535\|ref\|ZP_02375409.1\| 1-(5-phosphoribosyl)-5-[(5-phosphoribosylamino)methylideneamino] imi...	214.0	[0..1]	[243..1]
HIS4_BURCM - 1-(5-phosphoribosyl)-5-[(5-phosphoribosylamino)methylideneamino] imidazole-4-carboxamide isomerase O... HIS4_BURA4 - 1-(5-phosphoribosyl)-5-[(5-phosphoribosylamino)methylideneamino] imidazole-4-carboxamide isomerase O... gi\|170699507, gi... - gi\|170699507\|ref\|ZP_02890549.1\| phosphoribosylformimino-5-aminoimidazole carboxamide ribotide isomer... gi\|158343732, gi... - gi\|158343752\|gb\|ABW35570.1\| phosphoribosylformimino-5-aminoimidazole carboxamide ribotide isomerase ...	214.0	[0..1]	[243..1]
gi\|121593189, gi... - gi\|121593189\|ref\|YP_985085.1\| 1-(5-phosphoribosyl)-5-[(5-phosphoribosylamino)methylideneamino] imida...	213.0	[0..1]	[243..12]

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Predicted Domain #1

Region A:
Residues: [1-247]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MLLIPAIDLK DGQCVRLKQG DMDQATVFSE DPAAMARHWV DQGARRLHLV DLNGAFVGKP  60
   61 RNEAAIKAII AEVGSEIPVQ LGGGIRDLNT IERWLDDGLS YVIIGTAAVK NPGFLQDACT 120
  121 AFGGHIIVGL DARDGKVATD GWSKLTGHEV VDLARKYEDY GVESIIYTDI GRDGMLQGIN 180
  181 IDATVKLAQS VSIPVIASGG LSSLKDIDHL CAVESEGVEG VICGRAIYSG DLNFREAQDH 240
  241 ADKLGAA

[Run NCBI BLAST on this sequence.]

Detection Method:	PSI-BLAST
Confidence:	43.0
Match:	1vzwA
Description:	Crystal structure of the bifunctional protein Pria
Matching Structure (courtesy of the PDB):

Predicted functions:

Term	Confidence	Notes
imidazoleglycerol-phosphate synthase activity	8.63799159510181	bayes_pls_golite062009
catalytic activity	2.44231061702877	bayes_pls_golite062009
transferase activity, transferring pentosyl groups	1.13340776845419	bayes_pls_golite062009
indole-3-glycerol-phosphate synthase activity	0.549444136526559	bayes_pls_golite062009
tryptophan synthase activity	0.426391242491024	bayes_pls_golite062009
lyase activity	0.258652421339738	bayes_pls_golite062009

TMHMM	2.0c	PSIPRED	v2.61
SignalP	3.0	COILS	1999
DISOPRED	v0.1	NCBI nr	06/2007
PSI-BLAST	2.2.18	FFAS	ffas03
PDB	06/2007	Pfam	22
HMMER	2.3.2

View Structure Prediction Details

Top Sequence Alignment Hits

Predicted functions: