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View Structure Prediction Details

Protein: ODP22_ARATH
Organism: Arabidopsis thaliana
Length: 539 amino acids
Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16



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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for ODP22_ARATH.

Description E-value Query
Range
Subject
Range
ODP23_ARATH - Dihydrolipoyllysine-residue acetyltransferase component 3 of pyruvate dehydrogenase complex, mitocho...
485.0 [0..2] [539..4]

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Predicted Domain #1
Region A:
Residues: [1-109]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MASRIINHSK KLKHVSALLR RDHAVAVRCF SNSTHPSLVG REDIFKARLN YSSVERISKC  60
   61 GTGNVTMLSG ISTTSTKLSS PMAGPKLFKE FISSQMRSVR GFSSSSDLP

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 12.39794
Match: 2qf7A
Description: No description for 2qf7A was found.

Predicted Domain #2
Region A:
Residues: [110-295]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 PHQEIGMPSL SPTMTEGNIA RWLKKEGDKV APGEVLCEVE TDKATVEMEC MEEGFLAKIV  60
   61 KEEGAKEIQV GEVIAITVED EDDIQKFKDY TPSSDTGPAA PEAKPAPSLP KEEKVEKPAS 120
  121 APEAKISKPS SAPSEDRIFA SPLARKLAED NNVPLSSIKG TGPEGRIVKA DVEDFLASGS 180
  181 KETTAK

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 25.154902
Match: 1zy8K
Description: The crystal structure of dihydrolipoamide dehydrogenase and dihydrolipoamide dehydrogenase-binding protein (didomain) subcomplex of human pyruvate dehydrogenase complex.
Matching Structure (courtesy of the PDB):

Predicted Domain #3
Region A:
Residues: [296-539]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 PSKQVDSKVP ALDYVDIPHT QIRKVTASRL AFSKQTIPHY YLTVDTCVDK MMGLRSQLNS  60
   61 FQEASGGKRI SVNDLVIKAA ALALRKVPQC NSSWTDEYIR QFKNVNINVA VQTENGLYVP 120
  121 VVKDADKKGL STIGEEVRFL AQKAKENSLK PEDYEGGTFT VSNLGGPFGI KQFCAVINPP 180
  181 QAAILAIGSA EKRVVPGTGP DQYNVASYMS VTLSCDHRVI DGAIGAEWLK AFKGYIETPE 240
  241 SMLL

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 85.69897
Match: 1c4tA
Description: Dihydrolipoamide succinyltransferase
Matching Structure (courtesy of the PDB):

Predicted functions:

Term Confidence Notes
S-succinyltransferase activity 10.0778678835755 bayes_pls_golite062009
dihydrolipoyllysine-residue succinyltransferase activity 10.0778678835755 bayes_pls_golite062009
dihydrolipoyllysine-residue acetyltransferase activity 9.65061123545754 bayes_pls_golite062009
dihydrolipoamide S-acyltransferase activity 9.64995677986911 bayes_pls_golite062009
S-acetyltransferase activity 9.49696044977584 bayes_pls_golite062009
S-acyltransferase activity 8.45313874919036 bayes_pls_golite062009
pyruvate dehydrogenase activity 8.17557182322815 bayes_pls_golite062009
transferase activity, transferring acyl groups other than amino-acyl groups 6.86215901871647 bayes_pls_golite062009
acyltransferase activity 6.83977352892719 bayes_pls_golite062009
succinyltransferase activity 6.58826720904067 bayes_pls_golite062009
pyruvate dehydrogenase (acetyl-transferring) activity 6.40483178382327 bayes_pls_golite062009
acetyltransferase activity 6.08159176722072 bayes_pls_golite062009
oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor 5.93985773477717 bayes_pls_golite062009
transferase activity, transferring acyl groups 4.60481199262496 bayes_pls_golite062009
alpha-ketoacid dehydrogenase activity 4.42757758312016 bayes_pls_golite062009
carnitine O-acyltransferase activity 2.87366177129153 bayes_pls_golite062009
oxidoreductase activity, acting on the aldehyde or oxo group of donors 2.54513901872655 bayes_pls_golite062009
catalytic activity 1.51562638409295 bayes_pls_golite062009
O-acyltransferase activity 1.33852311685118 bayes_pls_golite062009
O-palmitoyltransferase activity 1.22729402619659 bayes_pls_golite062009
carnitine O-palmitoyltransferase activity 1.22729402619659 bayes_pls_golite062009
transferase activity 1.08341671157927 bayes_pls_golite062009
carnitine O-acetyltransferase activity 1.00868366840715 bayes_pls_golite062009
binding 0.801074244553007 bayes_pls_golite062009
O-acetyltransferase activity 0.54660034926676 bayes_pls_golite062009
protein binding 0.00454070917775817 bayes_pls_golite062009

YRC Informatics Platform - Version 3.0
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