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View Structure Prediction Details

Protein: THA2_ARATH
Organism: Arabidopsis thaliana
Length: 355 amino acids
Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16



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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for THA2_ARATH.

Description E-value Query
Range
Subject
Range
ARGD_METJA - Acetylornithine aminotransferase OS=Methanocaldococcus jannaschii GN=argD PE=3 SV=1
ARGD_METJA - Acetylornithine aminotransferase OS=Methanocaldococcus jannaschii (strain ATCC 43067 / DSM 2661 / JA...
290.0 [0..2] [353..34]

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Predicted Domain #1
Region A:
Residues: [1-355]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MVTPTTIRTV DLRSDTVTKP TESMRSAMAN AEVDDDVLGN DPTALRLEKE VAEIAGKEAA  60
   61 MFVPSGTMGN LISVLVHCDE RGSEVILGDD SHIHIYENGG VSSLGGVHPR TVKNEEDGTM 120
  121 EIGAIEAAVR SPKGDLHHPV TKLICLENTQ ANCGGRCLPI EYIDKVGELA KKHGLKLHID 180
  181 GARIFNASVA LGVPVKRIVQ AADSVSICLS KGIGAPVGSV IVGSKKFITK ARWLRKTLGG 240
  241 GMRQIGVLCA AALVALHENV AKLEDDHKKA RVLAEGLNRI ERLRVNVAAV ETNIIYVDIP 300
  301 EDPKFGAEEA CKSLEDVGVL VIPQATFRIR IVLHHQISDV DVEYVLSCFE KIFHS

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 63.154902
Match: 2fm1A
Description: Crystal structure of L-ALLO-threonine aldolase (tm1744) from Thermotoga maritima at 2.25 A resolution
Matching Structure (courtesy of the PDB):

Predicted functions:

Term Confidence Notes
glycine dehydrogenase (decarboxylating) activity 2.63753310919108 bayes_pls_golite062009
oxidoreductase activity, acting on the CH-NH2 group of donors, disulfide as acceptor 2.63753310919108 bayes_pls_golite062009
transferase activity 2.59075614411581 bayes_pls_golite062009
threonine aldolase activity 2.36742457876142 bayes_pls_golite062009
catalytic activity 2.29878871754893 bayes_pls_golite062009
L-aspartate:2-oxoglutarate aminotransferase activity 1.87460342369605 bayes_pls_golite062009
transferase activity, transferring nitrogenous groups 1.28316822767388 bayes_pls_golite062009
transaminase activity 1.24990480711889 bayes_pls_golite062009
O-phospho-L-serine:2-oxoglutarate aminotransferase activity 0.994935084630764 bayes_pls_golite062009
methyltransferase activity 0.681623261233707 bayes_pls_golite062009
transcription regulator activity 0.636782746250952 bayes_pls_golite062009
transferase activity, transferring one-carbon groups 0.60304280865376 bayes_pls_golite062009
nucleic acid binding 0.526698053525422 bayes_pls_golite062009
DNA binding 0.516618701017633 bayes_pls_golite062009
binding 0.450641761940864 bayes_pls_golite062009
glycine C-acetyltransferase activity 0.367632398200112 bayes_pls_golite062009
structural molecule activity 0.347975812448725 bayes_pls_golite062009
glycine hydroxymethyltransferase activity 0.271623203801431 bayes_pls_golite062009
transcription factor activity 0.188693175079415 bayes_pls_golite062009
pyridoxal phosphate binding 0.16957228630576 bayes_pls_golite062009
vitamin B6 binding 0.16957228630576 bayes_pls_golite062009
L-allo-threonine aldolase activity 0.140152839681041 bayes_pls_golite062009
carbon-carbon lyase activity 0.11598778799668 bayes_pls_golite062009
4-aminobutyrate transaminase activity 0.0779403509221881 bayes_pls_golite062009

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