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View Structure Prediction Details

Protein: gi|227554043, gi...
Organism: Enterococcus faecalis HH22
Length: 183 amino acids
Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16



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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for gi|227554043, gi....

Description E-value Query
Range
Subject
Range
tr|E4RCV5|E4RCV5... - Cro/CI family transcriptional regulator OS=Pseudomonas putida (strain BIRD-1) GN=PPUBIRD1_5062 PE=4 ...
tr|I7BAY6|I7BAY6... - Cro/CI family transcriptional regulator OS=Pseudomonas putida (strain DOT-T1E) GN=T1E_2779 PE=4 SV=1
gi|26991944, gi|... - gi|26991944|ref|NP_747369.1| Cro/CI family transcriptional regulator [Pseudomonas putida KT2440], gi...
127.0 [0..5] [183..1]
gi|49081740 - gi|49081740|gb|AAT50270.1| PA5301 [synthetic construct]
127.0 [0..5] [182..1]
gi|95113300, gi|... - gi|95113300|emb|CAK18028.1| putative transcriptional regulator [Pseudomonas entomophila L48], gi|104...
gi|95113300 - gi|95113300|emb|CAK18028.1| putative transcriptional regulator [Pseudomonas entomophila L48]
126.0 [0..5] [183..1]
gi|148550378, gi... - gi|82739390|ref|ZP_00902194.1| Helix-turn-helix motif [Pseudomonas putida F1], gi|82713513|gb|EAP486...
125.0 [0..6] [183..19]
gi|218774633, gi... - gi|218894404|ref|YP_002443274.1| putative transcriptional regulator [Pseudomonas aeruginosa LESB58],...
gi|115588669, gi... - gi|53726745|ref|ZP_00141783.2| COG1396: Predicted transcriptional regulators [Pseudomonas aeruginosa...
gi|15600494, gi|... - gi|9951617|gb|AAG08686.1|AE004943_2 probable transcriptional regulator [Pseudomonas aeruginosa PAO1]...
gi|254238004, gi... - gi|254238004|ref|ZP_04931327.1| hypothetical protein PACG_04117 [Pseudomonas aeruginosa C3719], gi|1...
gi|126197190, gi... - gi|254243812|ref|ZP_04937134.1| hypothetical protein PA2G_04640 [Pseudomonas aeruginosa 2192], gi|19...
gi|11352188 - pir||E82982 probable transcription regulator PA5301 [imported] - Pseudomonas aeruginosa (strain PAO1...
124.0 [0..5] [182..1]
gi|78365654, gi|... - gi|78365654|ref|ZP_00835939.1| Helix-turn-helix motif:Cupin region [Shewanella sp. PV-4], gi|7836219...
124.0 [0..5] [182..1]
SO1265 - transcriptional regulator putative
gi|24372846, gi|... - gi|24372846|ref|NP_716888.1| transcriptional regulator, putative [Shewanella oneidensis MR-1], gi|24...
123.0 [0..5] [182..1]
gi|68347618, gi|... - gi|70733319|ref|YP_263093.1| DNA-binding protein [Pseudomonas fluorescens Pf-5], gi|68347618|gb|AAY9...
123.0 [0..5] [182..1]
gi|68544420, gi|... - gi|68544420|ref|ZP_00584069.1| Helix-turn-helix motif [Shewanella baltica OS155], gi|68517873|gb|EAN...
gi|160859837, gi... - gi|160874315|ref|YP_001553631.1| XRE family transcriptional regulator [Shewanella baltica OS195], gi...
gi|151364315, gi... - gi|152999697|ref|YP_001365378.1| cupin 2 domain-containing protein [Shewanella baltica OS185], gi|15...
gi|149116513, gi... - gi|217974352|ref|YP_002359103.1| transcriptional regulator, XRE family [Shewanella baltica OS223], g...
123.0 [0..5] [182..1]
gi|77385747, gi|... - gi|77461744|ref|YP_351251.1| transcriptional regulator [Pseudomonas fluorescens Pf0-1], gi|77385747|...
122.0 [0..5] [182..1]

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Predicted Domain #1
Region A:
Residues: [1-183]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MEINTIIGNN LKKIRQEKKL TLDELAGITG VSKGMLSQIE KGTTNPTINT IWKISNGLNV  60
   61 PYTYLLEDDY VKENPVVKKT ETVTQHSEDH SYRVFNYYSD NQERNFELFQ FELDPGKKYQ 120
  121 AVGHSKRSTE YVMVIQGALA LEVGGQRYLL PKDAAMYFDA NQVHTYINDG TEKVQAVVIN 180
  181 YYT

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 17.30103
Match: 1y9qA
Description: Crystal Structure of HTH_3 family Transcriptional Regulator from Vibrio cholerae
Matching Structure (courtesy of the PDB):

Predicted functions:

Term Confidence Notes
catalytic activity 0.77242843392921 bayes_pls_golite062009
transcription regulator activity 0.707930119310256 bayes_pls_golite062009
nucleic acid binding 0.437474993266492 bayes_pls_golite062009
RNA polymerase II transcription factor activity 0.29966985317584 bayes_pls_golite062009
DNA binding 0.241621391797808 bayes_pls_golite062009
binding 0.206341280654185 bayes_pls_golite062009
sequence-specific DNA binding 0.20324889750334 bayes_pls_golite062009
transcription repressor activity 0.0485771867742395 bayes_pls_golite062009

YRC Informatics Platform - Version 3.0
Created and Maintained by: Michael Riffle