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View Structure Prediction Details

Protein: gi|227074699, gi...
Organism: Enterococcus faecalis TX0104
Length: 295 amino acids
Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16



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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for gi|227074699, gi....

Description E-value Query
Range
Subject
Range
gi|89101161, gi|... - gi|89101161|ref|ZP_01173994.1| dimethyladenosine transferase [Bacillus sp. NRRL B-14911], gi|8908412...
245.0 [0..6] [292..4]
RSMA_STRP2 - Ribosomal RNA small subunit methyltransferase A OS=Streptococcus pneumoniae serotype 2 (strain D39 /...
gi|168492040, gi... - gi|183573705|gb|EDT94233.1| dimethyladenosine transferase [Streptococcus pneumoniae CDC0288-04], gi|...
gi|25286073 - gi|25286073|pir||E98096 dimethyladenosine transferase (EC 2.1.1.-) [imported] - Streptococcus pneumo...
RSMA_STRR6 - Ribosomal RNA small subunit methyltransferase A OS=Streptococcus pneumoniae (strain ATCC BAA-255 / R...
243.0 [0..5] [290..1]
gi|242244296, gi... - gi|242244296|ref|ZP_04798733.1| dimethyladenosine transferase [Streptococcus pneumoniae TCH8431/19A]...
RSMA_STRPJ - Ribosomal RNA small subunit methyltransferase A OS=Streptococcus pneumoniae (strain ATCC 700669 / Sp...
gi|183571617, gi... - gi|183571617|gb|EDT92145.1| dimethyladenosine transferase [Streptococcus pneumoniae SP195], gi|16848...
KSGA_STRPN, RSMA... - Ribosomal RNA small subunit methyltransferase A OS=Streptococcus pneumoniae GN=rsmA PE=3 SV=2, Dimet...
gi|147929973, gi... - gi|149021935|ref|ZP_01835922.1| dimethyladenosine transferase [Streptococcus pneumoniae SP23-BS72], ...
gi|147928127, gi... - gi|148993153|ref|ZP_01822719.1| dimethyladenosine transferase [Streptococcus pneumoniae SP9-BS68], g...
RSMA_STRPN - Ribosomal RNA small subunit methyltransferase A OS=Streptococcus pneumoniae serotype 4 (strain ATCC ...
RSMA_STRZT - Ribosomal RNA small subunit methyltransferase A OS=Streptococcus pneumoniae (strain Taiwan19F-14) GN...
242.0 [0..5] [290..1]
RSMA_GEOKA - Ribosomal RNA small subunit methyltransferase A OS=Geobacillus kaustophilus (strain HTA426) GN=rsmA ...
RSMA_GEOKA, KSGA... - Ribosomal RNA small subunit methyltransferase A OS=Geobacillus kaustophilus GN=rsmA PE=3 SV=1, Dimet...
242.0 [0..6] [289..4]
RSMA_STAS1 - Ribosomal RNA small subunit methyltransferase A OS=Staphylococcus saprophyticus subsp. saprophyticus...
241.0 [0..2] [290..1]
RSMA_LACSS - Ribosomal RNA small subunit methyltransferase A OS=Lactobacillus sakei subsp. sakei (strain 23K) GN=...
241.0 [0..5] [293..2]
KSGA_STAEP - (Q8CQU5) Dimethyladenosine transferase (EC 2.1.1.-) (S-adenosylmethionine-6-N', N'-adenosyl(rRNA) di...
RSMA_STAEQ - Ribosomal RNA small subunit methyltransferase A OS=Staphylococcus epidermidis (strain ATCC 35984 / R...
gi|251809801, gi... - gi|251809801|ref|ZP_04824274.1| dimethyladenosine transferase [Staphylococcus epidermidis BCM-HMP006...
RSMA_STAES - Ribosomal RNA small subunit methyltransferase A OS=Staphylococcus epidermidis (strain ATCC 12228) GN...
240.0 [0..2] [291..1]
RSMA_STRA5 - Ribosomal RNA small subunit methyltransferase A OS=Streptococcus agalactiae serotype V (strain ATCC ...
RSMA_STRA5, KSGA... - Ribosomal RNA small subunit methyltransferase A OS=Streptococcus agalactiae serotype V GN=rsmA PE=3 ...
gi|76586400, gi|... - gi|76798247|ref|ZP_00780496.1| dimethyladenosine transferase [Streptococcus agalactiae 18RS21], gi|7...
240.0 [0..5] [291..1]
RSMA_STRA3, KSGA... - Ribosomal RNA small subunit methyltransferase A OS=Streptococcus agalactiae serotype III GN=rsmA PE=...
gi|77159783, gi|... - gi|77414160|ref|ZP_00790325.1| dimethyladenosine transferase [Streptococcus agalactiae 515], gi|7715...
RSMA_STRA3 - Ribosomal RNA small subunit methyltransferase A OS=Streptococcus agalactiae serotype III (strain NEM...
240.0 [0..5] [291..1]
RSMA_BACLD - Ribosomal RNA small subunit methyltransferase A OS=Bacillus licheniformis (strain ATCC 14580 / DSM 1...
240.0 [0..4] [291..2]

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Predicted Domain #1
Region A:
Residues: [1-295]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MTDYKEIATP SRTKEILKKH GFSFKKSLGQ NFLTEPNILR KIVETAGINQ QTNVVEVGPG  60
   61 IGALTEQLAM NAAQVVAFEI DDRLIPVLAD TLSRYDNVTV VHQDVLKADL VETTNQVFQE 120
  121 KYPIKVVANL PYYITTPIMM HFLESSLDVA EMVVMMQKEV ADRIAAKPGT KAYGSLSIAV 180
  181 QYFMEASVAF IVPKTVFVPQ PNVDSAIIKL TRRATPAVTV TNEKEFFKLT KASFQLRRKT 240
  241 LWNNLTHFYG KDEQTVAWLK ESLAEAEIDP SRRGETLSLE EFARLSNALE KNKPV

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 52.0
Match: 1qyrA
Description: 2.1 Angstrom Crystal structure of KsgA: A Universally Conserved Adenosine Dimethyltransferase
Matching Structure (courtesy of the PDB):

Predicted functions:

Term Confidence Notes
methyltransferase activity 4.15445027778357 bayes_pls_golite062009
rRNA methyltransferase activity 4.09362182773099 bayes_pls_golite062009
transferase activity, transferring one-carbon groups 4.07153733729662 bayes_pls_golite062009
N-methyltransferase activity 3.67177992319602 bayes_pls_golite062009
protein methyltransferase activity 3.5512266163483 bayes_pls_golite062009
S-adenosylmethionine-dependent methyltransferase activity 3.39429041855776 bayes_pls_golite062009
RNA methyltransferase activity 3.07428840534971 bayes_pls_golite062009
histone methyltransferase activity 2.49492581548369 bayes_pls_golite062009
transferase activity 2.22303238506686 bayes_pls_golite062009
DNA-methyltransferase activity 2.14498896320526 bayes_pls_golite062009
protein-arginine N-methyltransferase activity 2.06652984530965 bayes_pls_golite062009
arginine N-methyltransferase activity 2.06652984530965 bayes_pls_golite062009
rRNA (adenine) methyltransferase activity 1.83964463328968 bayes_pls_golite062009
rRNA (adenine-N6,N6-)-dimethyltransferase activity 1.75675289134467 bayes_pls_golite062009
histone-arginine N-methyltransferase activity 1.63076727020333 bayes_pls_golite062009
transcription regulator activity 1.42049721553167 bayes_pls_golite062009
protein-arginine omega-N monomethyltransferase activity 1.26493190370687 bayes_pls_golite062009
catalytic activity 1.25333584501255 bayes_pls_golite062009
tRNA methyltransferase activity 1.12859857407629 bayes_pls_golite062009
rRNA (guanine) methyltransferase activity 1.10713374933008 bayes_pls_golite062009
DNA binding 1.03011331296251 bayes_pls_golite062009
nucleic acid binding 0.731396842794323 bayes_pls_golite062009
histone methyltransferase activity (H4-R3 specific) 0.720411427168235 bayes_pls_golite062009
site-specific DNA-methyltransferase (adenine-specific) activity 0.703178429468566 bayes_pls_golite062009
protein-arginine omega-N asymmetric methyltransferase activity 0.606920378432989 bayes_pls_golite062009
binding 0.546744797014504 bayes_pls_golite062009
mitochondrial transcription initiation factor activity 0.481383105532041 bayes_pls_golite062009
tRNA (cytosine-5-)-methyltransferase activity 0.299393192819978 bayes_pls_golite062009
tRNA (cytosine)-methyltransferase activity 0.299393192819978 bayes_pls_golite062009
rRNA (guanine-N1-)-methyltransferase activity 0.234572322347698 bayes_pls_golite062009
rRNA (uridine-2'-O-)-methyltransferase activity 0.188049877065151 bayes_pls_golite062009
transcription factor binding 0.149382105526243 bayes_pls_golite062009
rRNA (uridine) methyltransferase activity 0.130647573658872 bayes_pls_golite062009

YRC Informatics Platform - Version 3.0
Created and Maintained by: Michael Riffle