YRC Public Data Repository - Protein Structure Prediction

Protein:	gi\|227074699, gi...
Organism:	Enterococcus faecalis TX0104
Length:	295 amino acids
Reference:	Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16

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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for gi|227074699, gi....

Description	E-value	Query Range	Subject Range
gi\|89101161, gi\|... - gi\|89101161\|ref\|ZP_01173994.1\| dimethyladenosine transferase [Bacillus sp. NRRL B-14911], gi\|8908412...	245.0	[0..6]	[292..4]
RSMA_STRP2 - Ribosomal RNA small subunit methyltransferase A OS=Streptococcus pneumoniae serotype 2 (strain D39 /... gi\|168492040, gi... - gi\|183573705\|gb\|EDT94233.1\| dimethyladenosine transferase [Streptococcus pneumoniae CDC0288-04], gi\|... gi\|25286073 - gi\|25286073\|pir\|\|E98096 dimethyladenosine transferase (EC 2.1.1.-) [imported] - Streptococcus pneumo... RSMA_STRR6 - Ribosomal RNA small subunit methyltransferase A OS=Streptococcus pneumoniae (strain ATCC BAA-255 / R...	243.0	[0..5]	[290..1]
gi\|242244296, gi... - gi\|242244296\|ref\|ZP_04798733.1\| dimethyladenosine transferase [Streptococcus pneumoniae TCH8431/19A]... RSMA_STRPJ - Ribosomal RNA small subunit methyltransferase A OS=Streptococcus pneumoniae (strain ATCC 700669 / Sp... gi\|183571617, gi... - gi\|183571617\|gb\|EDT92145.1\| dimethyladenosine transferase [Streptococcus pneumoniae SP195], gi\|16848... KSGA_STRPN, RSMA... - Ribosomal RNA small subunit methyltransferase A OS=Streptococcus pneumoniae GN=rsmA PE=3 SV=2, Dimet... gi\|147929973, gi... - gi\|149021935\|ref\|ZP_01835922.1\| dimethyladenosine transferase [Streptococcus pneumoniae SP23-BS72], ... gi\|147928127, gi... - gi\|148993153\|ref\|ZP_01822719.1\| dimethyladenosine transferase [Streptococcus pneumoniae SP9-BS68], g... RSMA_STRPN - Ribosomal RNA small subunit methyltransferase A OS=Streptococcus pneumoniae serotype 4 (strain ATCC ... RSMA_STRZT - Ribosomal RNA small subunit methyltransferase A OS=Streptococcus pneumoniae (strain Taiwan19F-14) GN...	242.0	[0..5]	[290..1]
RSMA_GEOKA - Ribosomal RNA small subunit methyltransferase A OS=Geobacillus kaustophilus (strain HTA426) GN=rsmA ... RSMA_GEOKA, KSGA... - Ribosomal RNA small subunit methyltransferase A OS=Geobacillus kaustophilus GN=rsmA PE=3 SV=1, Dimet...	242.0	[0..6]	[289..4]
RSMA_STAS1 - Ribosomal RNA small subunit methyltransferase A OS=Staphylococcus saprophyticus subsp. saprophyticus...	241.0	[0..2]	[290..1]
RSMA_LACSS - Ribosomal RNA small subunit methyltransferase A OS=Lactobacillus sakei subsp. sakei (strain 23K) GN=...	241.0	[0..5]	[293..2]
KSGA_STAEP - (Q8CQU5) Dimethyladenosine transferase (EC 2.1.1.-) (S-adenosylmethionine-6-N', N'-adenosyl(rRNA) di... RSMA_STAEQ - Ribosomal RNA small subunit methyltransferase A OS=Staphylococcus epidermidis (strain ATCC 35984 / R... gi\|251809801, gi... - gi\|251809801\|ref\|ZP_04824274.1\| dimethyladenosine transferase [Staphylococcus epidermidis BCM-HMP006... RSMA_STAES - Ribosomal RNA small subunit methyltransferase A OS=Staphylococcus epidermidis (strain ATCC 12228) GN...	240.0	[0..2]	[291..1]
RSMA_STRA5 - Ribosomal RNA small subunit methyltransferase A OS=Streptococcus agalactiae serotype V (strain ATCC ... RSMA_STRA5, KSGA... - Ribosomal RNA small subunit methyltransferase A OS=Streptococcus agalactiae serotype V GN=rsmA PE=3 ... gi\|76586400, gi\|... - gi\|76798247\|ref\|ZP_00780496.1\| dimethyladenosine transferase [Streptococcus agalactiae 18RS21], gi\|7...	240.0	[0..5]	[291..1]
RSMA_STRA3, KSGA... - Ribosomal RNA small subunit methyltransferase A OS=Streptococcus agalactiae serotype III GN=rsmA PE=... gi\|77159783, gi\|... - gi\|77414160\|ref\|ZP_00790325.1\| dimethyladenosine transferase [Streptococcus agalactiae 515], gi\|7715... RSMA_STRA3 - Ribosomal RNA small subunit methyltransferase A OS=Streptococcus agalactiae serotype III (strain NEM...	240.0	[0..5]	[291..1]
RSMA_BACLD - Ribosomal RNA small subunit methyltransferase A OS=Bacillus licheniformis (strain ATCC 14580 / DSM 1...	240.0	[0..4]	[291..2]

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Predicted Domain #1

Region A:
Residues: [1-295]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MTDYKEIATP SRTKEILKKH GFSFKKSLGQ NFLTEPNILR KIVETAGINQ QTNVVEVGPG  60
   61 IGALTEQLAM NAAQVVAFEI DDRLIPVLAD TLSRYDNVTV VHQDVLKADL VETTNQVFQE 120
  121 KYPIKVVANL PYYITTPIMM HFLESSLDVA EMVVMMQKEV ADRIAAKPGT KAYGSLSIAV 180
  181 QYFMEASVAF IVPKTVFVPQ PNVDSAIIKL TRRATPAVTV TNEKEFFKLT KASFQLRRKT 240
  241 LWNNLTHFYG KDEQTVAWLK ESLAEAEIDP SRRGETLSLE EFARLSNALE KNKPV

[Run NCBI BLAST on this sequence.]

Detection Method:	PSI-BLAST
Confidence:	52.0
Match:	1qyrA
Description:	2.1 Angstrom Crystal structure of KsgA: A Universally Conserved Adenosine Dimethyltransferase
Matching Structure (courtesy of the PDB):

Predicted functions:

Term	Confidence	Notes
methyltransferase activity	4.15445027778357	bayes_pls_golite062009
rRNA methyltransferase activity	4.09362182773099	bayes_pls_golite062009
transferase activity, transferring one-carbon groups	4.07153733729662	bayes_pls_golite062009
N-methyltransferase activity	3.67177992319602	bayes_pls_golite062009
protein methyltransferase activity	3.5512266163483	bayes_pls_golite062009
S-adenosylmethionine-dependent methyltransferase activity	3.39429041855776	bayes_pls_golite062009
RNA methyltransferase activity	3.07428840534971	bayes_pls_golite062009
histone methyltransferase activity	2.49492581548369	bayes_pls_golite062009
transferase activity	2.22303238506686	bayes_pls_golite062009
DNA-methyltransferase activity	2.14498896320526	bayes_pls_golite062009
protein-arginine N-methyltransferase activity	2.06652984530965	bayes_pls_golite062009
arginine N-methyltransferase activity	2.06652984530965	bayes_pls_golite062009
rRNA (adenine) methyltransferase activity	1.83964463328968	bayes_pls_golite062009
rRNA (adenine-N6,N6-)-dimethyltransferase activity	1.75675289134467	bayes_pls_golite062009
histone-arginine N-methyltransferase activity	1.63076727020333	bayes_pls_golite062009
transcription regulator activity	1.42049721553167	bayes_pls_golite062009
protein-arginine omega-N monomethyltransferase activity	1.26493190370687	bayes_pls_golite062009
catalytic activity	1.25333584501255	bayes_pls_golite062009
tRNA methyltransferase activity	1.12859857407629	bayes_pls_golite062009
rRNA (guanine) methyltransferase activity	1.10713374933008	bayes_pls_golite062009
DNA binding	1.03011331296251	bayes_pls_golite062009
nucleic acid binding	0.731396842794323	bayes_pls_golite062009
histone methyltransferase activity (H4-R3 specific)	0.720411427168235	bayes_pls_golite062009
site-specific DNA-methyltransferase (adenine-specific) activity	0.703178429468566	bayes_pls_golite062009
protein-arginine omega-N asymmetric methyltransferase activity	0.606920378432989	bayes_pls_golite062009
binding	0.546744797014504	bayes_pls_golite062009
mitochondrial transcription initiation factor activity	0.481383105532041	bayes_pls_golite062009
tRNA (cytosine-5-)-methyltransferase activity	0.299393192819978	bayes_pls_golite062009
tRNA (cytosine)-methyltransferase activity	0.299393192819978	bayes_pls_golite062009
rRNA (guanine-N1-)-methyltransferase activity	0.234572322347698	bayes_pls_golite062009
rRNA (uridine-2'-O-)-methyltransferase activity	0.188049877065151	bayes_pls_golite062009
transcription factor binding	0.149382105526243	bayes_pls_golite062009
rRNA (uridine) methyltransferase activity	0.130647573658872	bayes_pls_golite062009

TMHMM	2.0c	PSIPRED	v2.61
SignalP	3.0	COILS	1999
DISOPRED	v0.1	NCBI nr	06/2007
PSI-BLAST	2.2.18	FFAS	ffas03
PDB	06/2007	Pfam	22
HMMER	2.3.2

View Structure Prediction Details

Top Sequence Alignment Hits

Predicted functions: